Dean Elgar, Keegan Petersen and Temba Bavuma hit half-centuries as South Africa reached stumps on 278-5 on day one of the second Test against Bangladesh.
The Proteas are chasing victory at St George's Park in Port Elizabeth to seal a 2-0 series victory after they claimed a resounding win in the first match, Keshav Maharaj claiming 7-32 to skittle the touring Tigers for 53.
Captain Elgar's 70 helped to build the platform on Friday, as Petersen's 64 and Bavuma's 67 provided further impetus, with Taijul Islam (3-77) the pick of the Bangladesh bowlers.
The hosts opted to bat after winning the toss and started in positive fashion, with openers Sarel Erwee and Elgar sharing 52 inside 12 overs before the former was caught behind off Khaled Ahmed (2-59) for 24.
Elgar continued in imperious form to reach his third consecutive half-century as the Proteas skipper mounted an 81-run partnership with Petersen, before edging left-arm spinner Taijul behind.
Petersen cruised to a third fifty in as many Tests, but he was soon dismissed lbw on review by Taijul.
South Africa's dominance wilted in the final session with Bavuma and Ryan Rickelton (42) falling in quick succession to slip catches off Khaled and Taijul respectively.
The unbeaten Kyle Verreynne and Wiaan Mulder defied the Bangladesh attack before the close, and the home side will look to capitalise to build a healthy advantage on Saturday.
Bavuma's century wait continues but Proteas dominate
South Africa have won four of their past five Tests, including each of their last two. Elgar and Petersen have been keen drivers of that recent Proteas success and again contributed here.
But Bavuma, with batting conditions easing later in the day, will have been frustrated to miss out on a second Test century, with his lone ton coming all the way back in January 2016 against England.
Ebadot toils as Taijul excels
Ebadot Hossain typified Bangladesh's bowling problems as he went wicketless, conceding 75 from his 16 overs at a hefty economy of 4.68. Taijul, by contrast, went for just 2.4 an over for his three-wicket haul.
The Tigers will need Ebadot and Co to support Taijul if they are to claw their way back and beat the Proteas for the first time in 14 attempts in the longest format.