Svitolina was the only top-five seed in action not to lose as she defeated home hope Caroline Garcia 6-1 6-3 to book a last-eight date with Nadia Podoroska, who was a 2-6 6-2 6-3 victor against Barbora Krejcikova.
In Svitolina's half of the draw, top seed Halep was surprisingly beaten 6-1 6-2 by Iga Swiatek and Bertens – ranked fifth at Roland Garros – suffered a 6-4 6-4 loss to Martina Trevisan.
There are now just three of the top 10 seeds in the women's draw still alive in Paris, and third seed Svitolina is the highest-ranked player left.
SVITOLINA NOT FOCUSING ON EXODUS OF SEEDS
Svitolina will be hoping it is third time lucky in the French Open quarter-finals after reaching this stage again, as she previously did in 2015 and 2017.
The pressure may increase on the Ukrainian given how many seeds have already been eliminated, but the 26-year-old is trying not to pay attention to the rest of the draw.
"Of course, I'm the highest seed left, but no one is going to give me the trophy just because I'm the highest left," Svitolina said.
"So, I have to work for it. I try to not look so much ahead."
HALEP SEEKS COMFORT IN CHOCOLATE
Halep had not dropped a set prior to her fourth-round encounter with Swiatek, but she was stunned by the Pole, who lost only three games in reaching her first grand slam quarter-final.
However, the Romanian – the French Open champion in 2018 – was keen to take solace in a sweet treat afterwards.
"I'm not going to ruin the whole year just for a match," Halep said.
"Of course, it's not easy to take it, but I'm used to some tough moments in this career. So I will have a chocolate and I will be better tomorrow."
BERTENS: OUTSIDERS HAVING THEIR MOMENT
There was an even bigger shock on Suzanne-Lenglen as Bertens suffered a straight-sets defeat to world number 159 Trevisan.
Bertens was asked to explain the number of surprising results across both the men's and women's draws, and the Dutchwoman suggested the lack of preparation for the leading players was a factor.
"No one really has played a lot," she claimed.
"I think then you can see that everything can happen in a tournament like this."
Halep was leading the two-time defending champion 6-0 2-1 in Rome when Pliskova retired in tears because of injury.
The Czech called a medical timeout between sets and had treatment on her lower back and leg.
It is Halep's third consecutive title, with the two-time grand slam champion on a 14-match winning streak after a triumph that further solidifies her status as French Open favourite.
The 2018 Roland Garros champion is not willing to burden herself with the weight of expectation despite her hugely impressive form.
"It's just another tournament," Halep said. "I'm not going to put pressure on myself. I've played really well this year, with three titles already.
"I've played so much on clay, so I feel confident and happy that I'll have a chance to play another grand slam this year.
"I'm not going to let myself be bothered by things like the weather. I'll just be happy to take positives from this tournament and go there smiling.
"It's a dream for everyone to win the grand slam tournament from the first day, so it's my dream as well, but I'm not thinking that far.
"I just want to go there, get used to the courts and the atmosphere, and try to win every match I play. Every match is a battle, so I'll be ready for it."
Pliskova had won three of the previous four meetings with Halep but was full of appreciation for the Romanian after falling short this time around.
"Disappointing for me to not finish today, but Simo, obviously too strong," said Pliskova.
"I always have to be 100 per cent to play a good match against you. Congratulations for the whole week. I think you deserve the title."
The 2018 Roland Garros champion, the most experienced player in the draw at this year's competition, fell to a 2-6 6-2 6-1 loss against her unseeded opponent.
Halep, who is now coached by Serena Williams' former coach Patrick Mouratoglou, is the latest big name to suffer an early exit on clay this year.
The 30-year-old, who fought off a comeback from lucky loser Nastasja Schunk on Tuesday, looked to be cruising after the first set.
But Halep failed to navigate a fiery response from Zheng, who blazed through the second set to tie things up before an impressive rout in the third in her first appearance in Paris.
It marks revenge for the teenager as well, having fallen to Halep at the semi-final stage of the Melbourne Summer Set 1 earlier this year.
It continues a mixed 2022 for the Romanian so far, whose best finishes were victory in Victoria, followed by reaching the final four at the Dubai Tennis Championships and Indian Wells Masters.
Zheng will now face either 13th seed Jelena Ostapenko or France's Alize Cornet in the third round, with the pair set to play later on Thursday.
The 2018 Roland Garros champion became the latest big name to make a shock departure from Paris inside the first week after blowing a first set lead to lose 2-6 6-2 6-1.
It marked a major scalp for the unseeded Zhang, who previously lost to Halep in January, and was arguably the biggest win of the Chinese teenager's career at her competition debut.
But Halep, who looked to be in cruise control early on, revealed she suffered an unexpected setback that threw her rhythm in her post-match comments, though she has now recovered.
"I was playing well at the start," she stated. "I had a break in the second set, but then something happened. I just lost it.
"It was just a panic attack. I didn't know how to handle it, because I don't have [them] often. I don't really know why it happened, because I was leading the match. I was playing well
"After the match, [it] was pretty tough. But now I'm good. I'm recovered, and I will learn from this episode. It's good that now I can smile."
On her overall time at Roland Garros, Halep admitted she was happy to come through it unscathed, adding: "Tomorrow is a new day.
"I know it's like a cliche, but it's a new day, and I'll wake up motivated to keep working. [I've] no injury, which is really good. Now I'm in a good place."
The 2018 Roland Garros champion came through her first-round clash against 18-year-old lucky loser Nastasja Schunk 6-4 1-6 6-1 on Tuesday.
Number 19 seed Halep, who is now coached by Serena Williams' former coach Patrick Mouratoglou, has played 42 main-draw matches at the French Open – more than any other player in this year's competition.
Asked if that experience brings with it more pressure, Halep told a media conference: "Well, hopefully I put as much pressure as possible on myself because I love pressure. It's good to have it and it keeps you focused.
"Everyone is playing well, so it's a big challenge every match. We are at Grand Slam, so it's always tough. But I'm here to face these challenges, and I'm here to give my best.
"So, I will focus on myself. I will try to do what I have to do, and that's it. Then we will see.
"I will think about the next round only, and then if I will win it, I will think about the next one.
"I don't want to look further than that. It's important to just stay focused and to play the next match."
Halep will face Zheng Qinwen in the second round after the Chinese player overcame Maryna Zanevska 6-3 6-1 on Monday.
Having already recorded her best tour-level run on grass by reaching the final eight, Gauff recorded a superb 7-5 6-4 win over two-time grand slam finalist Pliskova.
Gauff – who reached her first grand slam final at Roland Garros last month, saved four set points in the opener before roaring to victory in one hour and 37 minutes, and was delighted to have overcome a tough opponent in the world number seven.
"I'm super happy with how I played today," Gauff said on court after the win. "Playing her on grass, with her serve, how flat she hits the ball, it was really tough to be honest.
"A first semi-final on grass is pretty cool, and also I feel like the opponents I've played this week haven’t been easy, especially today, so I'm proud of myself about that."
Gauff will face Jabeur for a spot in the final after the Tunisian fought back from one set down in a 6-7 (3-7) 6-2 6-2 win over Aliaksandra Sasnovich, who entered the contest having won 26 matches during an impressive year.
The other semi-final will see Maria Sakkari face Belinda Bencic, after the world number six cruised to a 6-0 6-3 win over Daria Kasatkina and Bencic beat Veronika Kudermetova 3-6 6-3 6-3.
In the Birmingham Classic, meanwhile, Simona Halep raced to a 6-4 6-1 win over Katie Boulter to reach the final four, but third seed Camila Giorgi fell to a 6-3 6-2 loss to Brazil's Beatriz Haddad Maia, who has now won eight consecutive games on grass.
While that pair will face off in one of Saturday's semi-finals, eighth seed Zhang Shuai will face Sorana Cirstea in the other. Zhang overcame Dayana Yastremska 7-5 6-4 and sixth seed Cirstea beat Donna Vekic 5-7 6-3 6-4.
Gauff, who has never been ranked higher than her current spot of 11th, will overtake Emma Raducanu and likely Daria Kasatkina to move up to ninth when the next rankings are released after prevailing in an exceptionally tight match against her Belarussian opponent.
Incredibly, both Gauff and Sabalenka won exactly 131 points each, posting identical success rates on service points (77-of-131) and return points (54-of-131).
Gauff will be considered one of the favourites in the tournament after world number one Iga Swiatek was sensationally eliminated by Brazil's Beatriz Haddad Maia. Swiatek was sloppy, committing nine double faults to just one from her opponent.
Two-time grand slam winner Simona Halep defeated rising Swiss talent Jil Teichmann 6-2 7-5, utilising her dominant first serve to get the job done. Halep converted 82 per cent (32-of-39) of her accurate first serves into points, compared to just 59 per cent (29-of-49) for Teichmann.
World number seven Jessica Pegula had to save a match point on her way to a comeback 3-6 6-0 7-5 win against reigning Canadian Open champion Camila Giorgi, booking her quarter-final clash against Yulia Putintseva after the Kazakhstani beat Alison Riske 6-3 7-5.
Third seed Maria Sakkari went down 1-6 7-6 (11-9) 3-6 against 14th seed Karolina Pliskova, and the Czech will take on China's Qinweng Zheng after she eliminated Canada's last remaining contender Bianca Andreescu 7-5 5-7 6-2.
In the final match of the night, Tokyo Olympics gold medalist Belinda Bencic was incredibly impressive against world number eight Garbine Muguruza, prevailing 6-1 6-3.
Haddad Maia enjoyed a fine day, beating second seed and two-time major champion Simona Halep 6-3 2-6 6-4 in a rearranged semi-final (postponed from Saturday due to rain).
Zhang followed that up by battling past Halep's Romanian compatriot Sorana Cirstea 4-6 6-1 7-6 (7-5), setting up a second career match with Haddad Maia.
The Brazilian struggled in the opening stages, with Zhang racing into the lead before squandering an opportunity to go 3-0 up.
Haddad Maia soon recovered to level at 3-3 before Zhang was forced to retire with an apparent neck injury, with the Chinese player 5-4 down in the first set.
That handed the world number 32 her second straight title after success at the Nottingham Open last week, with Ons Jabeur and Iga Swiatek the only others to record multiple WTA Tour triumphs this year.
Haddad Maia also became the first Brazilian lift the trophy in the tournament's 40-year history, surpassing the previous best result by a player from Brazil when Gisele Miro made the second round in 1989.
Halep and Kerber will miss the WTA Premier Mandatory tournament in Indian Wells due to injuries, it was announced on Friday.
Indian Wells champion in 2015, world number two Halep cited a foot injury for her withdrawal.
Kerber – a three-time grand slam champion – succumbed to an ongoing left leg problem, replaced in the main draw by Taylor Townsend.
"I'm incredibly disappointed to have to withdraw from the 2020 BNP Paribas Open. Unfortunately the foot injury that I picked up before Dubai is still causing me trouble and I will be unable to recover in time to travel to Indian Wells," Halep, the two-time major champion, said.
"It is without doubt one of the highlights of the tennis calendar for me and I will be really sad to miss it, but I'm already looking forward to being back in 2021!"
Bianca Andreescu won Indian Wells last year and the US Open champion could still defend her title, despite injuries preventing her from playing in 2020.
Halep has now reached a WTA final in 12 consecutive seasons after easing to a 6-0 6-1 victory over her teenage opponent.
The two-time grand slam champion faced Kostyuk at Indian Wells three weeks ago and was forced to come from a break down in the first set before prevailing in straight sets.
No such recovery effort was required in Cluj, with Halep progressing to her third final in Romania having twice won the Bucharest Open.
"I really wanted to play the final here. It's a home tournament and always when I come here, I feel great," Halep said.
"I'm really happy, motivated and I'm looking forward to playing the final tomorrow.
"I knew that I had to play a little bit faster, more aggressive and to open the court a little bit more. There [at Indian Wells], she didn't miss very much as she did today, but I think I took the ball faster and quicker, and the serve helped me today."
"I'm just trying to give my best, trying to be aggressive and enjoy. When I smile inside, it looks better outside. I have the whole country with me when I play at home, so that's why I'm motivated, that's why I feel safe and strong on the court, and I always want to play my best.
"I won twice in Bucharest and, hopefully, tomorrow's the lucky three, but if not, it's still a good result and it's good to be home."
Halep is unlikely to have it so easy in the final, which sees her face the in-form Anett Kontaveit, who will have added motivation on Sunday.
Kontaveit needed just over an hour to defeat Rebecca Peterson 6-3 6-2, her 25th win in her last 27 matches.
Victory over Halep would see Kontaveit beat Ons Jabeur to the eighth and final spot at the WTA Finals in Guadalajara. However, Halep has won all three of their previous meetings.
At the Courmayeur Open, Clara Tauson will face Donna Vekic in the final after they overcame Liudmila Samsonova and Jasmine Paolini respectively.
Halep was a 6-4 6-4 winner against Alize Cornet, who defeated her in the fourth round of the Australian Open in January, and will face seventh seed Danielle Collins next.
It was only the Romanian's second win in her six matches against Cornet, though she needed two chances to serve out both sets.
Azarenka needed just 68 minutes to see of Viktorija Golubic, dropping just five points behind her first serve and winning 12 out of 14 from the final three games to complete a 6-3 6-0 triumph.
It only took Gauff two minutes more to see off the challenge of Kerber, who has now won just two of her eight matches on the WTA Tour this year.
Leylah Fernandez came from behind to claim an impressive 1-6 6-2 6-2 victory over 16th seed Anastasia Pavlyuchenkova, while Madison Keys went down 6-4 6-4 to Anhelina Kalinina.
Aliaksandra Sasnovich's 3-6 7-6 (7-4) 6-1 win over Veronika Kudermetova secured her a second-round match against second seed Paula Badosa.
Belinda Bencic overcame Elisabetta Cocciaretto 6-4 6-2, Shuai Zhang set up a match with Aryna Sabalenka by beating Martina Trevisan 6-4 6-2, and Petra Martic will face Anett Kontaveit after besting Karolina Muchova 6-2 3-6 6-1.
There were also wins for Daria Kasatkina and Yulia Putintseva before rain interrupted Ajla Tomljanovic's match against Camila Giorgi when the Australian was 6-3 4-2 up.
Former world number one Halep, champion in Qatar back in 2014, was off the pace as Caroline Garcia claimed just her second win in nine meetings against the Romanian with a 6-4 6-3 triumph.
Number 10 seed Svitolina also suffered an early exit after ending up on the wrong side of an almost three-hour slog, with Tereza Martincova eventually succeeding 6-7 (2-7) 7-5 7-6 (7-5).
But fifth favourite Muguruza – a two-time finalist, including in 2021 – did not have much as trouble as she outfought Sorana Cirstea 7-6 (7-4) 6-1 in a second-round contest, with Kontaveit coasting through to round three in similar fashion with a 6-2 6-3 win over Ana Konjuh.
Jelena Ostapenko, who is a former finalist in Doha and champion in Dubai last week, managed a sixth consecutive victory in the Middle East as she downed Oceane Dodin 6-4 6-2 to reach the second round, while 11th seed Elena Rybakina fell at the first hurdle to Jacques Cristian in a 6-4 6-3 loss.
Angelique Kerber, the 13th ranked player at the tournament, was another surprise first-round loser as she fell 4-6 6-3 6-2 to Jil Teichmann.
Cori Gauff secured her spot in the second round with a straightforward 6-2 6-3 victory over American compatriot Shelby Rogers, while 16th seed Elise Mertens battled to a 6-3 2-6 7-5 win over Jasmine Paolini.
Meanwhile, defending champion Petra Kvitova had no trouble easing past Irina-Camelia Begu 6-3 6-1, and Daria Kasatkina edged out Ajla Tomljanovic 6-4 6-7 (4-7) 6-2.
Halep landed 75 per cent of her first-serves and won those points at a rate of 82 per cent (27/33).
Martic's serve commanded much less respect, as she landed 69 per cent of her first-serves, but only won 36 per cent of those points (8/22).
After holding in her first service game, Martic allowed Halep to rattle off six consecutive games, with three double-faults assisting her Romanian opponent.
With the win, Halep booked a semi-final matchup against Poland's number three seed Iga Swiatek after she prevailed in her meeting with American Madison Keys in similar fashion.
World number 28 Collins triumphed 2-6 6-4 6-4 over the sixth seed Romanian, with the second-round match lasting two hours and 55 minutes.
Halep, who is a two-time winner in Montreal, was returning to the Tour for the first time in three months since suffering a calf tear against Angelique Kerber in Rome.
Collins, who has won titles recently in San Jose and Palermo, loomed as a tough first-up test for Halep, who broke twice to win the first set 6-2 as she generated eight break points to one.
The game turned from then on, as Collins sent down 4-1 aces in the second set and finished with 38 winners for the match.
Tokyo 2020 bronze medalist and third seed Elina Svitolina was bundled out in a second-round shock, losing 3-6 6-3 6-2 to Briton Johanna Konta.
Svitolina boasted a 5-0 record against Konta heading into the match but was beaten in a two-hour-and-11-minute struggle.
Top seed Aryna Sabalenka defeated former U.S. Open champion Sloane Stephens in three sets to secure her third-round spot.
Sabalenka fought back from the brink, rallying to win the last five games and triumph 7-6 (7-4) 4-6 6-4 over the American wildcard in a two hours and 25 minutes.
Fourth seed Karolina Pliskova came from behind to win 4-6 6-3 7-6 (7-2) over Donna Vekic, while Jessica Pegula also fought back after a slow start to topple 10th seed Anastasia Pavlyuchenkova 1-6 6-3 6-2.
Greek 11th seed Maria Sakkari won in three sets 6-4 6-7 6-4 over Veronika Kudermetova, while 13th seed Ons Jabeur responded after a lopsided first set to win 2-6 6-3 6-4 over Daria Kasatkina.
Cori Gauff progressed after being 5-0 up as Anastasia Potapova retired, while Amanda Anisimova, Camila Giorgi, Rebecca Marino and Sara Sorribes Tormo all won too.
Canadian local hope Marino will take on top seed Sabalenka, while Gauff faces Svitolina's conqueror Konta.
A series of upsets meant Jabeur was the only seed left in the tournament going into Thursday, but she was outfought by Halep, whose win-loss record in 2022 now stands at 11-1.
The result followed two years on from Halep beating Jabeur in the second round at the same tournament, on that occasion needing a third-set tie-break to get the better of the Tunisia. Halep went on to win the title on that occasion.
"It was a very tough match. Even if it's in two sets, it felt much harder than that," Halep said of Thursday's win.
"I had in my mind big time the match from 2020, it was so close and I knew I'd have to fight till the end."
Quoted on the WTA website, former Wimbledon and French Open winner Halep added: "I've been focused on what I have to do, and I wanted just to push Jabeur back because she has such a big game."
Halep will face Jelena Ostapenko in the last four after the big-hitting Latvian overcame Petra Kvitova 5-7 7-5 7-6 (11-9).
Kvitova led by a set and a break, and twice served for the match, yet Ostapenko prevailed to add the 2013 Dubai champion to the scalps of Sofia Kenin and Iga Swiatek this week.
Ostapenko, who triumphed in two hours and 39 minutes, has now reached at least the semi-finals in four of her last seven tournaments.
The other semi-final will be contested by Veronika Kudermetova and Marketa Vondrousova.
Kudermetova reached her third career WTA 500 semi-final after beating lucky loser Jil Teichmann 6-2 5-7 6-4 in two hours and 23 minutes.
Vondrousova, meanwhile, became just the third ever qualifier to reach the last four of the tournament thanks to a 7-5 6-4 win over Dayana Yastremska.
The world number two, who won the Dubai Duty Free Tennis Championships in February before the WTA Tour's suspension for the coronavirus pandemic, sealed a 6-2 7-5 victory on Sunday.
A very different story looked set to unfold after Mertens won the first two games, but Halep clicked into top gear to reel off six on the bounce and take the set.
When Halep continued her streak by breaking in the first game of the second set, the writing appeared to be on the wall for Mertens.
But the Belgian, chasing a sixth singles title, hit back immediately to keep her hopes alive.
Ultimately, however, the class of two-time grand slam winner Halep told and the Romanian will soon have to confirm whether she will seek to cash in on this form by competing at the US Open, which has suffered from a spate of withdrawals over COVID-19 fears.
The 12th seed has just returned from a calf muscle tear which saw her miss the French Open and Wimbledon, and was defeated by Danielle Collins in Montreal last week.
However, at 1-4 down in the second set she required medical attention for what she described as a "sharp pain" in her right leg, but after a rain delay, the Romanian came out of the blocks to claim a third-set bagel.
Halep progressed to the Round of 32 where she will play American Jessica Pegula.
Sunday's breakthrough National Bank Open winner Camila Giorgo was beaten in straight sets by Pegula 6-2 6-2.
Former world number one Victoria Azarenka needed only one hour and nine minutes to dispose of Ludmilla Samsonova and seal her spot in the last 32.
The Belarussian triumphed 6-2 6-3 over the Russian, dominating her first serve and breaking Samsonova five times throughout the match.
Tokyo 2020 gold medalist Belinda Bencic eased past Marketa Vondrousova 6-3 7-5 continuing her bright recent run, winning in one hour and 27 minutes.
In the final match of the day's play, Caroline Garcia defeated 2017 U.S. Open champion Sloane Stephens 7-6 (9-7) 4-6 6-4 in two hours and 33 minutes.
Dayana Yastremska, Bernarda Pera, Karolina Muchova, Ons Jabeur, Elena Rybakina, Veronika Kudermetova and Coco Gauff were all winners too.
Halep, who is aiming to rebuild her ranking in 2022 after an injury-hit second half of last year, was excellent with her return, particularly on Gauff's second serve to gain the edge.
The Romanian saved all four break points generated by Gauff, while she converted three of the nine break points that she created.
Halep, who started the year with victory at the Melbourne Summer Set 1 before a last-16 loss to Alize Cornet at the Australian Open, needed only one hour and 16 minutes to seal her progress.
She will next play Romanian compatriot Sorana Cirstea after the 26th seed won 5-7 6-1 6-0 against lucky loser Anna Kalinskaya.
Last year's US Open champion and British 11th seed Emma Raducanu was bundled out by Croatian world number 79 Petra Martic 6-7 (3-7) 6-4 7-5.
Raducanu had served for the match in the final set but the Croatian won the final three games. Martic triumphed in two hours and 46 minutes, reaching the last 16 at Indian Wells for the second time in her career.
Martic will face 28th seed Liudmila Samsonova who triumphed 6-4 7-6 (7-4) over Danka Kovinic.
Third seed Iga Swiatek came from a set down to win 6-7 (3-7) 6-2 6-1 over Clara Tauson in two hours and 18 minutes.
Swiatek has won seven straight matches and is unbeaten at WTA 1000 events this season, having triumphed in Doha last month.
The Pole will take on three-time major winner Angelique Kerber in the last 16 after the German won comfortably over Daria Kasatkina 6-2 6-1.
American 25th seed Madison Keys got past countrywoman Alison Riske 7-6 (7-4) 6-1, setting up a fourth-round meeting with British qualifier Harriet Dart who beat Kaia Kanepi in straight sets.
Top seed Halep, playing her first tournament since the resumption of the season, took less than an hour to wrap up a crushing 6-2 6-0 victory.
The two-time grand slam champion came through three-set contests with Polona Hercog and Barbora Krejcikova en route to the last eight, but had no such trouble in a one-sided quarter-final.
Halep broke three times in each set as lucky loser Frech, playing her sixth match of the week, was blown away by the Wimbledon champion.
The world number two, yet to confirm if she will play in the upcoming US Open, said: "The whole game was better today.
"I'm happy that I can play better and better day by day. It was a good one and I'll take it."
Halep will either face fellow Romanian Irina-Camelia Begu or Sara Sorribes Tormo for a place in the final, with the latter having taken the first set of their quarter-final before play was suspended due to rain.
Third seed Elise Mertens earlier overcame wildcard Eugenie Bouchard 6-4 1-6 6-4 and will take on Kristyna Pliskova, who advanced when Ana Bogdan retired due to injury when leading 5-2 in the first set.
The Romanian was a 6-3 2-6 6-3 victor, dropping a set for only the second time in the week, but standing firm in the clash that clocked in at over two hours.
That meant records for Haddad Maia, who has played the most WTA-level matches with three sets in 2022 (20) and spent over 12-and-a-half hours on the court at the Canada Open in 2022, more than any other player in a single WTA tournament this year.
Wimbledon semi-finalist Halep proved to be a step too far for the Brazilian, however, with the win marking her most significant honour since winning in Rome in 2020.
It was far from a vintage performance from the 30-year-old, who had nine double-faults in the match compared to Haddad Maia's two and left the door open for the South American - who was vying for victory in her first ever WTA 1000 event.
Halep had already clinched a return to the world top 10 by reaching the final in Toronto, the first time since her 373-week stint ended just over a week ago - which led to admissions that she considered calling it quits amid her decline.
A valiant comeback in 2022 has been one of the major stories of the calendar year though and, on the back of victory in Canada and a semi-final march at Wimbledon, will have high hopes for the U.S. Open.