Lukoki came through the ranks at Dutch giants Ajax before spells with PEC Zwolle, Bulgarian club Ludogorets and Turkish side Yeni Malatyaspor.
The 29-year-old, who won three Eredivisie titles with Ajax, signed for FC Twente on a two-year deal last June but suffered a cruciate ligament injury in pre-season training.
Lukoki had his contract terminated by Twente in February for what the club described as "events in his personal life".
Twente confirmed the passing of Lukoki on Monday in a statement that read: "This morning FC Twente received the terrible news that Jody Lukoki has passed away.
"The club is shocked and deeply moved by this tragic event. FC Twente sympathises with his loved ones and wishes them a lot of strength in processing this great loss."
Zwolle also paid tribute: "PEC Zwolle has learned with dismay and sadness of the far too early death of former player Jody Lukoki.
"Lukoki will forever be remembered as PEC Zwolle's first goalscorer in an official European game. PEC Zwolle wishes the relatives of Jody Lukoki a lot of strength to bear this enormous loss."
While Turkish side Yeni Malatyaspor added: "We learned with sadness the news that Jody Lukoki, who wore our club's jersey in the 2020-2021 Super League season, passed away.
"Our condolences to his family and community."
Lukoki represented the Netherlands at youth international level but opted to play for DR Congo, who he made his senior debut for in 2015.
All three caps for the Leopards came in friendly matches, with his last coming against Burkina Faso in 2020.
Milan's home fixture with Genoa, Udinese against Fiorentina, Parma's clash with SPAL and Brescia's trip to Sassuolo will also kick off in front of empty stadiums.
Inter's Europa League last-32 second-leg tie at home to Ludogorets on Thursday also took place without fans in attendance and a Serie A statement on Thursday confirmed their trip to Allianz Stadium would do likewise.
The Nerazzurri's fixture against Sampdoria was postponed last weekend in one of four Serie A abandonments.
Towns in northern Italy have been on lockdown after 229 confirmed cases of coronavirus, with seven people having died.
Speaking prior to the Ludogorets fixture, Inter boss and former Juve coach Antonio Conte told Sky Italia: "I think playing behind closed doors is not beautiful
"Football needs the public and to feel the whole atmosphere around it. It is the most beautiful thing.
"Having said that, we refer to the decisions made for health reasons, but I hope that everything will return to normal as soon as possible."
Inter are six points adrift of leaders Juve with a game in hand.
Christian Eriksen and Romelu Lukaku scored as Inter beat Ludogorets 2-0 in the first leg in Bulgaria, but reports have already suggested the San Siro return match could be played behind closed doors.
Inter's game against Sampdoria on Sunday was postponed over local health concerns, with Italian prime minister Giuseppe Conte confirming the fixture was one of several that would not go ahead.
Italy is battling to contain the virus, which is officially named Covid-19, after the deaths of two people and confirmation that dozens more have tested positive.
In a statement issued on Sunday, Ludogorets expressed their concern and appealed to Inter and UEFA to provide swift clarification.
The statement said: "FC Ludogorets have formally asked UEFA and FC Inter about the situation in the Italian region of Lombardy, whose capital is Milan. Coronavirus-infected cases have been reported there in recent days.
"More than 600 supporters of the Bulgarian champions are expected to support their favourites at the San Siro on Thursday (February 27) in the rematch of the 1/16 finals of the Europa League.
"Many of them have already purchased plane tickets, and there is organised bus travel from Bulgaria to Italy.
"Ludogorets expect an official statement from the European headquarters and a quick explanation from Inter about the situation in the city. If received, the club will immediately notify supporters of the situation in Milan by a message on its official website.
"PFC Ludogorets will liaise with Bulgarian diplomatic authorities on the situation in Italy."
Inter and Ludogorets will clash in the second leg of their last-32 tie at San Siro on Thursday without any supporters present due to concerns over the spread of the virus in Italy, where there have been more than 300 cases and 11 deaths.
The confirmation of the match taking place behind closed doors was taken on Tuesday and followed the clash between Antonio Conte's side and Sampdoria being one of four Serie A fixtures postponed on Sunday.
But there will be no restrictions for attending supporters or alterations to fixtures for any of the other Europa League matches on Thursday or the two Champions League contests taking place on Wednesday.
"All other UEFA matches scheduled this week will go ahead as planned and at this time there are no restrictions for attending supporters," read UEFA's statement.
"UEFA will continue to closely monitor the situation regarding Covid-19 and to liaise with relevant authorities in this respect."
