The 28-year-old initially announced his retirement from Test cricket in July 2019, citing a desire to focus on limited-overs matches.
However, he has now called time on his international career altogether.
The Pakistan Cricket Board (PCB) did not provide a reason for Amir's decision, but the bowler said earlier on Thursday that Pakistan management had left him feeling "mentally tortured".
"I am not going away from cricket but I am being pushed away from it," he told Samaa TV.
"The environment that has been created, I feel that I cannot play cricket under this management.
"I feel that I am leaving cricket at this time because I am being mentally tortured."
A statement from the PCB read: "PCB chief executive Wasim Khan spoke with Mohammad Amir this afternoon following reports that the fast bowler had announced his retirement from international cricket.
"The 28-year-old confirmed to the PCB chief executive that he has no desires or intentions of playing international cricket and, as such, he should not be considered for future international matches.
"This is a personal decision of Mohammad Amir, which the PCB respects, and as such, will not make any further comment on this matter at this stage."
Amir was handed a five-year ban and jailed in 2011 for his part in a spot-fixing scandal after bowling deliberate no-balls against England, returning to international action against New Zealand in January 2016.
Amir claimed 119 wickets and scored 751 runs in his Test career, taking 6-44 in his best bowling innings against West Indies in 2017.
Miller's knock came from just 40 balls faced and featured four fours and eight maximums, ensuring the hosts recovered from a lacklustre start that left them teetering at 28-3.
Abrar Ahmed had taken two wickets in the opening four overs and later added a third, while Shaheen Shah Afridi recorded figures of 3-22 as the Proteas were bowled out for 183.
However, much of the damage was done by Miller, the high point of his knock coming when he pounded three successive sixes off Abrar's bowling in the 10th over.
While he ultimately succumbed to Afridi's slow ball, his fine knock – and 48 off 24 balls for Linde – gave South Africa a respectable total to defend.
Pakistan captain Mohammad Rizwan made 74 off 62 balls and lasted the entire 20 overs after opening, but he received little support from elsewhere – Saim Ayub's 31 being the tourists' next-best score as seven of their batters finished in single figures.
Rizwan finally fell to Kwena Maphaka at the death with Pakistan needing 18 runs from the last five balls, after Linde had teed up South Africa's success with figures of 4-21.
Data Debrief: Miller downs favourite opponents once more
It is fair to say Miller enjoys facing Pakistan in the 20-over format. He has now scored 359 runs against them in T20Is overall.
This was just the Proteas' second victory in their last seven T20Is against Pakistan, and their first since April 2021, and they will have a chance to seal a series success in Centurion on Friday.
Milne returned from five years away from the national team when he played two ODIs against India in November, but the 30-year-old later missed two domestic games for the Wellington Firebirds.
In a statement, New Zealand said there were "concerns about his preparation" and it was "considered too big of a risk" to take Milne, leading to a "mutual agreement" he would be replaced by Blair Tickner.
New Zealand, the world's top-ranked team in ODIs, face Pakistan in three matches from January 9, before heading to India for another three-match series, starting on January 18.
Selector Gavin Larsen said: "Adam was very up front with us about his concerns around the lack of one-day bowling loading for the upcoming tours.
"After chatting to him, we agreed his preparation leading into the tour wouldn't be sufficient for him to cope with the demands of back-to-back, three-game ODI series. We appreciate his honesty and his genuine desire not to let the team down."
The pair were appointed in September 2019 and were under contract with the Pakistan Cricket Board (PCB) for another year.
However, Misbah and Waqar informed the PCB of their decision to leave on Monday ahead of the upcoming three ODIs and five T20Is against New Zealand, with the T20 World Cup in the United Arab Emirates and Oman also on the horizon.
Saqlain Mushtaq and Abdul Razzaq have joined the Pakistan management team as interim coaches for that New Zealand series, which begins on September 17.
Misbah's decision to step down was for family reasons amid the ongoing coronavirus pandemic, with the 47-year-old having recently spent time self-isolating in Jamaica after testing positive for COVID-19.
"The quarantine in Jamaica post the West Indies series provided me with an opportunity to reflect on the past 24 months as well as the schedule for international cricket ahead," Misbah said in a statement.
"Considering that I would have had to continue to spend considerable time away from my family and that too in a bio-secure environment, I have decided to step down from the role.
"I understand that the timing may not be ideal but I don't think I am in the right frame of mind for the upcoming challenges and it makes sense for someone fresh to step in and take the side forward.
"The past 24 months have been thoroughly enjoyable and I want to thank my team and the management for their support.
"I wish the Pakistan cricket team best of luck in the upcoming events and will continue to support them every time they will take the field to represent Pakistan."
Waqar's decision to step down was linked to Misbah's departure.
"After Misbah shared with me his decision and future plans, it was a straightforward one for me to resign as we had walked into the roles together, had worked collectively as a pair and now also step down together," Waqar said.
"Working with the Pakistan bowlers, including the youngsters, has been most satisfying as they have now started to show progress.
"Bio-secure environments in the past 16 months have had their impact, something we had never experienced during our playing days.
"The next eight months will be busy and exciting for the Pakistan team and, like in the past, I will continue to back and cheer them.
"I want to thank each and every member of the Pakistan cricket team set-up as we stayed united in good and bad days, and hope there will be brighter days ahead."
The shock double exit came two hours after Pakistan had named their squad for the T20 World Cup, as well as the warm-up internationals against New Zealand and England.
Asif Ali and Khushdil Shah were among the surprise inclusions in the 15-man selection.
Pakistan squad: Babar Azam (c), Asif Ali, Hasan Ali, Shaheen Afridi, Mohammad Hafeez, Mohammad Hasnain, Azam Khan, Shadab Khan, Sohaib Maqsood, Mohammad Nawaz, Haris Rauf, Mohammad Rizwan, Khushdil Shah, Imad Wasim, Mohammad Wasim.
Both players suffered fractured thumbs during training sessions in Queenstown last week and are yet to return to practice.
The Pakistan Cricket Board (PCB) confirmed on Monday that the duo could return for the second Test, which begins in Christchurch on January 3.
They will, however, sit out the opener in Mount Maunganui, with Imran Butt added to the 17-man squad and Mohammad Rizwan confirmed as the 33rd captain to lead the team in the longest format.
The first Test begins on Boxing Day, three days after the final Twenty20 international, with the hosts already 2-0 ahead in that series.
"It is disappointing to lose the T20I series against a well-settled New Zealand side, who utilised their resources and conditions to their advantage," head coach Misbah said.
"We need to up-skill and improve our individual and team performances, including in Tuesday's match, and the sooner we get these sorted the better it will be in term of player confidence and team results as 2021 will not be any easier as we have two major events.
"Contrary to the T20I side, the Test side appears to be pretty organised and we boast some experienced cricketers, both in the batting and bowling departments. With some competitive cricket on the tour now under the belt, I am hoping we will be a better outfit in the longer version of the game.
"Although it will be nearly two weeks to Babar's injury when the first Test starts, it will be hard on him and the team to play him without any net sessions.
I remain confident and optimistic that other players will rise to the occasion in Mount Maunganui and use the opportunity to rise to the occasion and put the disappointment of the T20I series behind them."
Pakistan squad for Tests: Mohammad Rizwan (captain for first Test), Abid Ali, Azhar Ali, Faheem Ashraf, Fawad Alam, Haris Sohail, Imran Butt, Mohammad Abbas, Naseem Shah, Sarfaraz Ahmed, Shadab Khan, Shaheen Afridi, Shan Masood, Sohail Khan, Yasir Shah (Babar Azam and Imam-ul-Haq not available for first Test).
Batsman Shafiq was on Wednesday omitted from a 35-man squad to face the Black Caps after a poor Test series in England.
Mohammad Amir and Shoaib Malik were also omitted from a touring party for three Twenty20 Internationals and two Tests against the Black Caps in December and January.
Uncapped Paceman Amad Butt, batsmen Danish Aziz and Imran Butt were included along with Rohail Nazir as the Pakistan selectors invested in youth.
Pakistan head coach Misbah, who named Mohammad Rizwan as Babar Azam's Test vice-captain and Shadab Khan as T20 deputy, says there can still be a way back for the 34-year-old Shafiq.
He said: "There are three major omissions from the side that toured England. Asad Shafiq has been left out due to lack of form after he managed 510 runs in his last 15 innings, including a total of 67 runs in England.
"Asad is an experienced batsman and I am sure he will utilise this time to work harder on his game in the domestic first-class matches so that he, like Sarfraz Ahmed, can reclaim his form and be back in contention for the upcoming Tests against South Africa and Zimbabwe.
"Shoaib Malik and Mohammad Amir are not part of the white-ball matches as for this tour we have opted to invest, develop and focus on the promising and emerging players who are likely to be available to Pakistan for all formats."
The first T20 will be staged at Eden Park on December 18 and the Test series gets under way at Bay Oval, Mount Maunganui on December 26.
Pakistan squad:
Abid Ali, Abdullah Shafique, Fakhar Zaman, Imam-ul-Haq, Shan Masood, Zeeshan Malik, Babar Azam (captain), Azhar Ali, Danish Aziz, Fawad Alam, Haider Ali, Haris Sohail, Hussain Talat, Iftikhar Ahmed, Imran Butt, Khushdil Shah, Mohammad Hafeez, Mohammad Rizwan, Rohail Nazir, Sarfraz Ahmed, Imad Wasim, Shadab Khan, Usman Qadir, Yasir Shah, Zafar Gohar, Amad Butt, Faheem Ashraf, Haris Rauf, Mohammad Abbas, Mohammad Hasnain, Mohammad Musa, Naseem Shah, Shaheen Shah Afridi, Sohail Khan, Wahab Riaz.
The former Pakistan batsman must quarantine for 10 days after he was the only member of the touring party to return a positive PCR test.
Misbah had been due to head home a day after Pakistan salvaged a 1-1 Test series draw with West Indies, winning by 109 runs at Sabina Park.
A Pakistan Cricket Board (PCB) statement said: "Pakistan head coach Misbah-ul-Haq has tested positive and, as such, will not depart for Lahore with his side later today (Wednesday).
"Misbah, who is asymptomatic, will now undergo a 10-day quarantine, following which he will depart for Pakistan.
"Misbah was the only Pakistan squad member who failed two pre-departure PCR tests. All other members will leave Jamaica as per schedule later today.
"The PCB is constantly in touch with Cricket West Indies who have confirmed that Misbah will be shifted to another hotel for the 10-day quarantine with a medical specialist assigned to look after his health and wellbeing."
Pakistan's next assignment is a home ODI series against New Zealand next month.
Former Pakistan captain Misbah was appointed as head coach and chief selector in September 2019.
The 46-year-old will continue to carry out selection responsibilities until a new chief selector starts work on December 1.
Misbah's decision to concentrate solely on his coaching role may have come as a result of the introduction of a new Pakistan Cricket Board (PCB) code of ethics, which was ratified in July.
That code aims to put greater emphasis on resolving issues of conflict of interest.
Misbah told PCB chief executive Wasim Khan in Islamabad last week during the National T20 Cup that he no longer wishes to head up the selection panel.
He said: "I have thoroughly enjoyed the dual roles but after reviewing the past 12 months and looking ahead at the workload in the next 24 months of my tenure, it is appropriate that I invest and dedicate all my time, energy and attention to one role from now on.
"Coaching is my passion and my ultimate objective remains to contribute to the development of players and help the side achieve bigger successes. When I was appointed last year, I was offered the coaching role first and then given the option to also head the selection committee, which I had graciously accepted.
"I am grateful to the Pakistan Cricket Board for their understanding and for supporting my thought process."
Despite the ongoing coronavirus pandemic resulting in India pulling out of fixtures in Sri Lanka and Zimbabwe, Pakistan are set to follow West Indies in touring England for three Tests and Twenty20s between August and September having named a 29-man squad on Friday.
West Indies arrived in England earlier this week ahead of Tests that will take place at bio-secure venues in Southampton and Manchester, and the Pakistan series appears likely to follow a similar format.
Even though the contests will likely be staged behind closed doors, they can still be lucrative to the England and Wales Cricket Board (ECB), with West Indies and Pakistan willing to tour a country still grappling with COVID-19.
That has raised suggestions that Pakistan have only decided to travel with the proviso England visit their country in future, something they have not done since the attack on the Sri Lanka team bus in Lahore in 2009.
"It is not in our minds that we are coming and keeping in view something that the ECB has to do for us in return," Pakistan head coach Misbah said.
"At the moment the PCB [Pakistan Cricket Board] is just thinking about the restart of international cricket. That is very important to us, to get the players back on the ground.
"Obviously, in a bigger picture, we are not expecting anything in return. Overall we want not just the ECB but all cricketing nations to help each other so this game can grow. It's important for the cricket fans in Pakistan and also for Pakistan cricket that countries start touring Pakistan."
The prospect of playing in empty stadiums is one few countries around the world have experience of.
However, having staged 'home' Tests in front of sparsely populated stadiums in the United Arab Emirates since the Lahore attack, Misbah believes Pakistan will be better prepared than most when cricket resumes.
"Nobody understands it better than us because we played much more cricket than any other team in the world with empty stadiums in the UAE," he said.
"Obviously in a bigger picture, if we want to resume international cricket, we have to start it from somewhere."
Misbah also said he was hoping for the best for ex-Pakistan captain Shahid Afridi after the latter revealed on Twitter that he had tested positive for coronavirus.
"My prayers are with him, all well wishes with him that he gets out of this soon," Misbah added.
“Throughout the COVID situation he was helping the poor, doing a very good job. I think he was doing a lot of work in the area of Balochistan and the northern areas just to help the people."
Hosts Pakistan fended off a mid-innings revival from Bangladesh, who improved from 107-5 to 214-6 before their last four wickets fell in quick succession.
Mithun, coming in at number six, held the innings together before falling for a battling 63, while Najmul Hossain Shanto weighed in with 44.
Pakistan's 19-year-old left-arm paceman Shaheen Afridi took 4-53, while Mohammad Abbas was economical and accurate in a supporting role, his 2-19 coming from 17 overs.
Bangladesh made a wretched start, losing Saif Hassan to the third ball of the morning and Tamim Iqbal in the next over, the openers both gone with just three runs on the board.
A stand of 59 between Najmul and Mominul Haque gave Bangladesh a platform of sorts, with the alliance ending when the latter fell for 30, edging Shaheen to wicketkeeper Mohammad Rizwan.
Najmul followed in much the same way, out for 44 when he was caught behind off Abbas' bowling.
Bangladesh were in trouble, five down, when Mahmudullah fell for 25 to a fine catch by Shafiq, giving Shaheen a third wicket.
Liton Das perished next, lbw for 33 to Haris Sohail after a Pakistan review. Taijul Islam made 24 before falling to the same bowler, with Shaheen then cleaning up Rubel Hossain for one.
Mithun impressed before gloving Naseem Shah to Rizwan, and his departure meant the innings was all over bar the shouting, with Abu Jayed run out in the next over.
Fading light meant Pakistan could not begin their reply before the close.
Bavuma, who replaced Quinton de Kock as skipper, could only manage one run with the bat at Centurion, but Rassie van der Dussen's unbeaten 123 helped South Africa to 273-6.
Captain Babar (103) struck 17 fours as he went at almost a run a ball, with Pakistan 186-2 when he departed.
However, they lost five further wickets for just 85 runs from there as South Africa threatened an unlikely turnaround, with some impressive death bowling from Andile Phehlukwayo fraying the nerves.
But Faheem Ashraf got Pakistan over the line off the final ball to give them a 1-0 lead in the three-match series.
South Africa were reduced to 55-4 after being put into bat by the tourists, whose early inroads owed to a blitz from Shaheen Shah Afridi (2-61), who removed openers Aiden Markram and De Kock before then catching Bavuma at third man off Mohammad Hasnain.
Van der Dussen's 116-run stand with David Miller (50) gave South Africa's innings momentum, though, with Phehlukwayo sharing a stand of 64 as the Proteas' centurion found crucial support from the lower order.
The impact of that assistance looked to be minimal when Pakistan set about their reply, Babar and opener Imam-ul-Haq (70) combining for 177 to lay the platform.
Mohammad Rizwan and Shadab Khan appeared to have steadied the ship after Anrich Nortje (4-51) accounted for Pakistan's talismen as he ripped through the middle order.
But there was to be great drama in the closing overs. Rizwan holed out to deep midwicket off Phehlukwayo and, when Shadab fell to the same bowler going for the big shot on the first delivery of the final over needing only three off six balls, comeback hopes were very much alive.
Phehlukwayo then produced three successive dot balls but Faheem took advantage of a slower ball and a wide delivery to produce the final three runs as Pakistan survived a nervier conclusion than was necessary.
Mark Wood (3-20) removed half of Pakistan's top six as England bowled out the hosts for 145 runs in 19 overs in Lahore, a reasonably low score considering Mohammad Rizwan top-scored with 63 off 46 balls.
However, England were unable to chase Pakistan's total down despite Moeen making a half-century off just 35 balls, not aided by finding themselves 31-3 after five overs.
And Moeen was frustrated with his team's display, telling reporters: "Of all the games so far, this was the most disappointing, the way we batted in particular.
"Obviously I'm disappointed we didn't chase those runs. I feel we're a better team than that. You have to see the situation of the game, and the conditions.
"All we needed was one partnership, a 60-70 run partnership would have won the game. We want to play this brand that is attacking but you also have to see the situation of the game and the conditions, things like that."
Moeen also spoke of his admiration of Rizwan while also reserving praise for Pakistan's debutant seamer Aamir Jamal, who bowled superbly in the last over to restrict England to seven runs when 15 would have won them the match.
"He's [Rizwan] a brilliant player, so hard to stop and so busy. He's somebody we can learn a lot off," Moeen added.
"He saw the situation and adapted today. He took the risks when he needed to and played properly when he needed to.
"[Jamal] was on debut, nervous, but he bowled really well.
"Two big hits and you’re done. I got one but unfortunately couldn't manage to get the other one. Sometimes you've just got to give it to him, it was a good last over."
West Indies Nicholas Pooran won the toss and sent the home team to bat. The visitors had immediate success when Babar Azam was dismissed in the first over bowled by Akeal Hosein, who got the Pakistan captain to nick one into the gloves of Shai Hope behind the stumps.
The West Indies had further success in the fifth over when Fahkar Azam skied a Romario Shepherd delivery and was caught by Shamarh Brooks for 10 to have Pakistan at 35-2.
Despite the loss of those two wickets, Pakistan maintained a healthy strike rate with Rizwan and Ali putting together a stand of 105 in 62 balls before Rizwan was caught in the deep by Odean Smith, who gifted Shepherd with his second wicket of the match.
Rizwan ran well between the wickets and hit 10 fours in his score of 78 from 52 balls.
The West Indies fought back with the wickets of Asif Ali removed by Oshane Thomas for 1 and Iftikhar Ahmed dismissed by Smith for seven as Pakistan slipped from 140-3 to 161-5.
However, Ali and Mohammad Nawaz, kept Pakistan above nine an over, the latter being rather brutal hitting three fours and two sixes in his unbeaten 10-ball 30.
Between them, they scored 30 from 11 balls before Ali was the last man out for 68 in the 20th over bowled by Dominic Drakes.
Drakes ended with figures of 1-43 from his four overs. Smith proved expensive with 1-52 from his four while Shepherd was the best of the bowlers with 2-43. Twenty-one of those runs came off his last over, the 19th of the innings.
At the time of publication, West Indies were 33-2 from four overs. Brandon King (1) and Nicholas Pooran (18) are the batsmen out.
The home side made 208-3 from 18.5 overs to win by seven wickets.
The Pakistan opening pair of Mohammad Rizwan and Captain Babar Azam were comfortable throughout the first powerplay, taking 60 from the six overs with Rizwan on 32 and Babar on 27.
The pair raced to 98-0 after 10 overs with Rizwan bringing up a half century, his second of the series, on the last ball of the 10th over, and Babar on 46.
A boundary off the first ball of the 11th over bowled by Oshane Thomas made Mohammad Rizwan the first batsman ever to score 2000 T20 runs in a calendar year.
Babar achieved his 50 off 40 balls in the 12th over.
Rizwan and Babar brought up their 150-run partnership in the 15th over, which ended with Pakistan 158-0, still needing a further 50 from 30 balls to secure the sweep.
Babar was finally dismissed for 79 on the first ball of the 16th over bowled by Odean Smith.
Rizwan’s brilliant innings of 87 from 45 balls was finally ended in the 18th over when he was caught off the bowling of Dominic Drakes leaving Pakistan on 184-2 needing 24 off 16 balls to win.
Fakhar Zaman was the next Pakistan batsman to go, caught in the 19th over off the bowling Romario Shepherd for 12 to leave them 195-3.
Pakistan got to their target off 18.5 overs thanks to a late cameo of 21 from seven balls from Asif Ali.
Earlier, The West Indies won the toss and elected to bat, posting an excellent 207-3 thanks to 64 from captain Nicholas Pooran.
He was well supported by Shamarh Brooks who got 49 and Brandon King who scored 43.
Shahnawaz Dahani was Pakistan's best bowler on the day with 1-23 from his four overs.
Mohammad Rizwan was named Man of the Match and, after his brilliant 203 runs in three matches, was also named Man of the Series.
Mohammad Hafeez (69 off 34 balls) and Babar Azam (56 from 44) took Pakistan up to an imposing 195-4 in the second match of the series at Old Trafford, two days after the opener was abandoned due to rain.
Jonny Bairstow laid the platform for England with a rapid 44, but they were 66-2 in the seventh over with Shadab Khan on a hat-trick after dismissing the wicketkeeper-batsman and Tom Banton.
Morgan blasted 66 off 33 balls in a third-wicked stand of 112 with Malan (54 not out), who hit the winning runs off the first ball of the last over to complete their third-highest successful T20 chase.
Babar and Fakhar Zaman (36) got the tourists off to a flyer after Morgan put them in, but Adil Rashid (2-32) ended an opening stand of 72 in the ninth over when the left-hander was taken by Banton.
The captain crunched Rashid for his seventh boundary wide of extra cover to reach a 37-ball half-century and Hafeez reached 2,000 T20I runs landmark by hooking Mahmood over the ropes.
Babar fell tamely to Rashid, but Hafeez took centre stage, imperiously launching Tom Curran for two sixes in a 16th over that cost 23 before departing in the last over of a brilliant innings for Pakistan.
Bairstow struck two sixes as England raced to 50 off 29 balls in a great start to the run chase, but his swashbuckling 24-ball knock ended when he top-edged Shadab to Imad Wasim.
Banton (20) was trapped in front off the next ball and Morgan survived a big lbw later in that brilliant over, an umpire's call verdict that Pakistan were left to rue along with the loss of Mohammad Amir to a hamstring injury.
Morgan and Malan cashed in on a great track to take England well on their way to victory, the captain facing just 27 balls to make his 13th T20I half-century.
The powerful Morgan cleared the ropes four times and although he was sent on his way by Haris Rauf in the 17th over, the composed Malan sealed it with a four after Sam Billings put England on the verge of victory with a couple of sublime boundaries.
Hafeez makes up for lost time, more brilliance from Babar
All-rounder Hafeez had not batted in a competitive match since featuring in the Pakistan Super League in March, but the veteran made up for lost time.
Hafeez turns 40 in October, but showed he has plenty of cricket left in him yet as he took the England attack to all parts, including drives and swats down the ground for four as he made a 12th T20 half-century for his country.
Babar timed the ball majestically from the start, showing how he rose to the top of the rankings in another high quality innings after making two half-centuries in the Test series loss to England.
Morgan and Malan masterclass
England needed a rebuilt when Shadab saw the back of both openers with, Banton - who scored a blistering half-century on Friday - foxed by a top spinner to follow Bairstow into the pavilion.
Experienced left-handers Morgan and Malan showed they were just the men for the job, the skipper taking the role of chief aggressor with some stunning clean striking.
Malan showed what great touch he is in when he creamed Shaheen Afridi for a sixth four of a classy knock to give England a series lead with one match to play at the same venue on Tuesday.
It was confirmed on Thursday that Roy would miss the upcoming T20 series against Pakistan due to a side strain he sustained in practice this week.
Roy will remain with the England set-up while he recovers, and will undergo rehabilitation ahead of the Australia white-ball series, which starts on September 4 in Southampton.
Though he will be shorn of one of his big hitters at the top of the order, Morgan is confident Roy – who made only 25 runs across three ODI innings in the recent series against Ireland – will return in time to face Australia.
"Unfortunately he tweaked his side two days ago, and will be ruled out for the three games in order to give him time to prepare for both series against Australia," Morgan told a news conference.
"At the moment we don't anticipate it being anything serious but we want to give him every chance to be fit for Australia, both series - T20s and 50 overs.
"So we'll see how he progresses over the next three or four days and be able to report back then."
Despite Roy's injury, England have not yet called up an official replacement, with Morgan feeling there is enough quality cover within the squad already.
"At the moment, given that we have a lot of flexibility, particularly with our allrounders in Joe Denly and Moeen Ali, and the reserve batters in the squad, at the moment we don't feel a need to pull anybody in for tomorrow," he added.
Liam Livingstone, Tom Banton and Dawid Malan appear to be the likely candidates to battle it out to take Roy's place.
"Dawid in particular has really put together an early establishment of a career that, every time he's available, he's put himself forward as the next man, simply by weight of runs and the rate at which he scores them," Morgan said.
"[Banton] naturally is a top-order batter, but at a time where we have top-order batters in abundance and actually lack middle-order players, it's sometimes difficult to get him in in the position that is his strength.
"We know what he can achieve at the top of the order, along with a number of other guys who bat in the top five. And so hopefully if he gets a chance he can take it."
Morgan and vice-captain Jos Buttler are among nine men to return after being forced to self-isolate due to a COVID-19 outbreak among the England squad during their series against Sri Lanka earlier this month.
That meant a completely fresh squad with a raft of debutants was called up for the ODI series versus Pakistan, with Ben Stokes captaining them to a superb 3-0 series win.
Stokes will now rest up, but Lancashire fast bowler Saqib Mahmood has been rewarded with a T20 call-up after taking nine wickets at 13.66 in the ODIs to collect the player-of-the-series award.
Similarly, Somerset all-rounder Lewis Gregory remains with the senior set-up after his superb 77 from 69 deliveries proved crucial alongside James Vince's century in England's thrilling chase of 332 at Edgbaston on Monday.
England T20I squad
Eoin Morgan (captain), Moeen Ali, Jonny Bairstow, Jake Ball, Tom Banton, Jos Buttler, Tom Curran, Lewis Gregory, Chris Jordan, Liam Livingstone, Saqib Mahmood, Dawid Malan, Matt Parkinson, Adil Rashid, Jason Roy, David Willey
Ben Stokes returned early from an injury lay-off to captain a hastily assembled side in the three-match series after England's first-choice squad were forced to isolate due to a coronavirus outbreak.
However, with Morgan and Co watching on from the sidelines, England's back-up brigade impressed in a 3-0 series triumph – James Vince scoring his maiden ODI century as he led a record run chase at Edgbaston to secure the third victory.
England's star names have returned for the T20I series, which starts on Friday, though Saqib Mahmood, who was named player of the series, and Lewis Gregory have been rewarded for their performances.
"They've done themselves the world of good, to be honest," Morgan said when asked of the players who stepped up to fulfil the ODI series.
"The one thing you look at when guys come in and out is a marked improvement from the time they [first] get the opportunity to the time the next opportunity arrives. The two guys mentioned [Mahmood and Gregory] and Vince were outstanding.
"I think everybody within the group was extremely proud to watch them play like they did, simply because it's the biggest compliment you can pay to anybody who played in the World Cup group, and the way we've played in the last five years has had such an impact on the game.
"Guys recognise that opportunities are few and far between but, when they do come, the method that the team plays is starting to resonate with people around the country, which is great.
"Over the last six years, with the amount of cricket we play, you don't get to enjoy the cricket as much as you'd like. But sitting back and watching the guys [and] the way the guys played was hugely satisfying. They played an exciting brand of cricket, they really enjoyed themselves, and the result came with that. It was hugely beneficial."
England have triumphed in five of their past six T20I home outings, and finished 2020 with three successive wins, meaning a victory at Trent Bridge will match their longest winning run on home soil in the format.
However, Pakistan won the most recent meeting between the teams last September, a five-run victory in Manchester in a series which finished 1-1.
One player Morgan will be unable to call on is Stokes, who has been rested as he recovers from the finger injury which had been set to keep him out of white-ball action this month.
"He dug us out of a huge hole coming back early from his injury and I think leading the way he did is a huge compliment to the leader he is within our side, how mature he has been as a leader and now a captain," Morgan said of Stokes.
"We gave him every chance to be fit. He hasn't played a lot of cricket and he's had some 'R and R' at home and feels quite fresh.
"The finger hasn't come along as he and the medical team would have liked, so it's important it's as good as it can be for the Test matches against India."
Mushfiqur scored 191 before he was dismissed in the third session on Saturday, as Bangladesh were eventually bowled out for 565.
After declaring on 448-6, Pakistan had been hoping to make inroads with the ball, but the day belonged to Bangladesh, with Shadman Islam (93), Mominul Haque (50), Litton Das (56) and Mehidy Hasan Miraz (77) helping Mushfiqur along the way as the tourists mounted a huge total in Rawalpindi.
Naseem Shah was the pick of Pakistan's bowlers with 3-93, while Mohammad Ali (2-88) eventually ended Mushfiqur's momentous stand.
Bangladesh still had time to do some damage with the ball late on, with Shoriful Islam (1-13) dismissing Saim Ayub in the third over of Pakistan's second innings.
The hosts trail by 94 runs ahead of the final day, with a draw almost certainly the best Pakistan can hope for.
Data Debrief: Mushfiqur makes his mark in style
This was Mushfiqur's 11th Test ton, but his first against Pakistan in the format, and he did it in fantastic fashion, falling just short of a double-century.
Mushfiqur had not been in great form on the road before this match, either. Indeed, he had scored fewer than 10 runs in four of his last five innings away from home, but he is now clear of Tamim Iqbal in second place on the list of the most Test hundreds for Bangladesh.
Abrar took seven wickets as Pakistan bowled England out for 281 on Friday, becoming the 13th Pakistani bowler to claim five wickets on debut before lunch.
Zak Crawley, Ben Duckett, Ollie Pope, Joe Root, and Harry Brook all fell to the 24-year-old in the first session, with Stokes and Will Jacks following later in the day as Abrar recorded the best figures by any spinner on Test debut for 14 years.
Asked by Sky Sports for his thoughts on a remarkable first Test outing, Abrar said he took particular pleasure in dismissing England's skipper.
"My favourite wicket was Ben Stokes, my favourite player," Abrar said through a translator. "I definitely thought about taking five wickets, but not so quickly!
"I cannot forget this day. I wanted to win this match for Pakistan, but also the coming matches as well.
"I started my journey with the Rashid Latif cricket academy in Karachi, then progressed to club cricket, divisional cricket, and then got picked up by the Pakistan Super League Karachi Kings franchise.
"I had two years out with a hairline fracture and then came back into the side."
England batsman Duckett was Abrar's second victim, and the 28-year-old is looking forward to further tussles with the Pakistan spinner after his remarkable introduction to Test cricket.
Asked if Abrar caught England by surprise, Duckett said: "I can only speak individually, I had my own plans for him, he was basically a leg spinner with a good googly, there was no real mystery to it.
"He bowled beautifully today. I'm sure we'll have our plans in the second innings, unfortunately for us, it was his day today.
"There was limited footage [of Abrar], but for me personally, I'd rather not know all of his tricks and worry about them, I'd rather focus on what I can do to him."
England hit back with late wickets from Jack Leach and James Anderson as Pakistan closed on 107-2, and Duckett is hopeful their attack will make inroads when play resumes.
"I'd say its level at the minute, we're a couple of quick wickets away from it being our day, so we'll have to see in the morning," he said. "I think the game's going to move forward really quickly."