Naomi Osaka and Victoria Azarenka withdrew from their respective tournaments on Saturday due to injuries.
Osaka, a three-time grand slam champion, opted out of her Gippsland Trophy semi-final against Elise Mertens.
Azarenka, meanwhile, was due to face Anett Kontaveit in the Grampians Trophy quarter-finals.
Osaka said her move was a cautious one ahead of the Australian Open, which begins on Monday.
"Sorry to Tennis Australia and the fans to have to withdraw today," she said, via the WTA.
"I have a niggling injury and in light of the Australian Open on the horizon, I need to be cautious. I look forward to competing next week."
It continues what has been a difficult build-up to the first grand slam of the year.
On Friday, Serena Williams withdrew from her semi-final at the Yarra Valley Classic due to a right shoulder injury.
It comes amid a busy schedule for players after Thursday's action was called off due to a coronavirus scare.
Birthday boy Djokovic eases into Geneva Open quarter-final with Hanfmann triumph
Novak Djokovic celebrated his 37th birthday by breezing into the Geneva Open quarter-finals after his comfortable straight-sets victory against Yannick Hanfmann.
The world number one made light work of Hanfmann, who defeated Andy Murray the day before, after a 6-3 6-3 victory in Switzerland on Wednesday.
Serbia's Djokovic saved nine of the 10 break points faced and won six straight games in the second set for a routine victory, responding emphatically after going 3-0 down.
The winner of a last-16 meeting between Denis Shapovalov and Tallon Griekspoor awaits in the last eight for Djokovic, who triumphed with little trouble on his 37th birthday.
Data Debrief: Age will not stop Djokovic
Having watched rivals Roger Federer and Rafael Nadal struggle for fitness in the latter stages of their career, Djokovic is showing no signs of slowing down before the French Open starts later this month.
Djokovic will be aiming to become the second player in the Open Era to secure a Grand Slam Singles title after turning 37, along with Ken Rosewall at the Australian Open 1972.
Raducanu to feature in Nottingham after withdrawing from French Open
Emma Raducanu will return to action at the Nottingham Open, as she steps up her return to action ahead of Wimbledon.
The 21-year-old withdrew from the French Open after instead choosing to prepare for the grass-court season.
On Wednesday, Raducanu was confirmed as a participant in Nottingham, with the tournament starting on June 8, three weeks prior to the start of Wimbledon.
The former US Open champion has played at the event twice before, but lost to Harriet Dart in 2021 and withdrew due to injury from a match against Viktorija Golubic the following year.
'Gladiator' Andy Murray could still prolong career, says Diego Schwartzman
Andy Murray is a "gladiator" and his love for tennis means he could yet prolong his career, according to former world number eight Diego Schwartzman.
Murray has endured a difficult few years with injuries, undergoing surgery on both hips in 2018 and 2019.
The three-time major champion has repeatedly said he is approaching the end of his career, revealing in February that he does not "plan on playing much past this summer".
Murray is currently preparing for what will likely be his final appearance at the French Open, having sat out five of the last six tournaments at Roland-Garros.
Schwartzman, however, feels Murray's love for the game could lead to him playing on for longer than anticipated.
"His life is tennis and I think he enjoys it. I think this is his legacy," Schwartzman – who won his only tour-level meeting with Murray in Antwerp in 2021 – told Stats Perform.
"No matter what you do, your age or how you are doing, if you really love the sport and you love what you do, you can do it and you can push hard for as many years and as many tournaments as you want.
"He's a fighter, a gladiator, and he's been doing the same since he was very young, and for us also, sharing tournaments and sharing moments, he has the passion out there.
"So, it's good to see these kinds of guys because tennis always needs guys who love the sport, and this is the one for sure."
Murray would surely have added to his one US Open title and two Wimbledon crowns if not for the presence of the 'big three' of Novak Djokovic, Rafael Nadal and Roger Federer. The Scot has lost five grand slam finals to Djokovic and one to Federer.
Schwartzman says the importance of preparation is the main thing he learned from being on tour with those three greats, though he refused to say who was the greatest of all time.
"I know them very well, playing them on court, outside of the court," the Argentine added. "The good thing for me and many guys who share the tournaments with them is how differently they prepare the tournaments.
"How differently they do things with food, with practice, with everything. It's crazy.
"I think, okay, 'in one small way he's the best to do this side of the game', and then the other one is the best [at another aspect], so it's not my thing, who the GOAT is."
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