Madison Keys is set to miss the Australian Open after testing positive for coronavirus.
The 2017 US Open runner-up announced on Thursday that she contracted COVID-19 before she was due to fly out for the first grand slam of the year.
Keys did not state she will definitely miss the major, which starts on February 8, but it appears the American will not make the trip to Melbourne.
The American wrote on Instagram: "Hi everyone, I wanted to let you know that I unfortunately tested positive for COVID-19 before I was supposed to fly to Australia.
"I'm very disappointed to not be able to play in the coming weeks after training hard in the off-season and knowing Tennis Australia and the tours did so much to make these events happen.
"I am self-isolating at home and will continue to follow all the necessary health precautions. I look forward to being back on tour next month."
It was revealed earlier in the day that three-time major winner Andy Murray has also tested positive for the virus, but still hopes to play in the Australian Open.
Meanwhile, world number 50 Tennys Sandgren was cleared to board a flight from the United States bound for Melbourne despite revealing he returned a new positive coronavirus test this week.
The American, twice a quarter-finalist at Melbourne Park, initially posted to social media on Wednesday that he had tested positive for the virus for a second time.
Although his first instance of having the illness was recorded in November, the 29-year-old's participation in the tournament appeared to be in doubt.
But as he continued to update followers through the day, it emerged he had been allowed to board his flight.
Players will only be allowed into Australia with proof of a negative test just prior to departure, or with approval to travel as a recovered case at the complete discretion of an Australian government authority.
Anyone wanting to travel out for the tournament who previously tested positive is required to provide additional and highly detailed medical information as proof they are a recovered case and no longer infectious or a risk to the community.
Jarry defeats Paul to set up Zverev showdown in Italian Open final
Nicolas Jarry defeated Tommy Paul in three sets on Friday to set up a showdown with Alexander Zverev in the Italian Open final.
The men's world number 24 prevailed 6-3 6-7 (3-7) 6-3 in a little under three hours in Rome to reach his first ATP Masters 1000 final.
Jarry earned the only break of serve in the eighth game of the opening set, but Paul - who dropped just one set in four matches en route to this stage - hit back in the second.
Birthday boy Paul lost serve to trail 4-2 at one stage, but he produced one of the shots of the tournament at the ideal moment and soon dragged it back to 4-4.
A gruelling set concluded with Paul taking the tie-break 7-3, but Jarry was unperturbed and won the deciding set with his fifth match point to see off Paul in a gruelling contest.
Data Debrief:
Jarry is the third male Chilean in the Open Era to reach the singles final of the Italian Open after Marcelo Rios (1997-98) and Fernando Gonzalez (2007).
The 28-year-old registered 13 aces against Paul to his opponent's seven and hit 35 winners to 19 in a deserved victory.
Zverev ends Tabilo's dream run to reach Italian Open final
Alexander Zverev fought back from the brink to reach the Italian Open final on Friday, overcoming Alejandro Tabilo by a 1-6 7-6 (7-4) 6-2 scoreline in the last four.
Zverev was punished for a slow start as Tabilo took the opener within 32 minutes, but the German fought back in a one-hour, 15-minute slog of a second set.
The 2017 Italian Open champion put his foot down from 3-3 in the second-set tie-break, with Tabilo potentially feeling the effects of a fine run that included a last-32 upset of Novak Djokovic.
Zverev upped the intensity in the final set and won a huge 94 per cent of points behind his first serve as his opponent wilted, the third seed reaching the Rome final for a third time.
Data Debrief: Zverev draws level with Becker
Zverev will now face either Nicolas Jarry or Tommy Paul in Sunday's final, which will be his 11th at ATP 1000 Masters level.
That tally pulls him level with Boris Becker for most such finals by a German player since the format's 1990 introduction.
Sabalenka defeats Collins to set up Swiatek rematch
Aryna Sabalenka defeated Danielle Collins 7-5 6-2 to set up yet another meeting with Iga Swiatek at the Italian Open.
Having defeated Collins en route to the final of the Madrid Open, which she lost to Swiatek, Sabalenka repeated the trick with a straight sets win over the American in Thursday's semi-final.
And the Belarusian's reward will be an immediate rematch with Swiatek.
The duo have met 10 times, including in Madrid earlier this month, with Swiatek winning seven times and Sabalenka claiming three victories.
This will be Sabalenka's first appearance in the Italian Open final.
She is the sixth player, along with Simona Halep (2017), Dinara Safina (2009), Serena Williams (2013), Ons Jabeur (2022), and Swiatek (2024) to have reached the final of both Madrid and Rome in the same season.
Data Debrief: Perfect record
Collins is the only player against whom Sabalenka has registered six wins without a loss in WTA events, while only against Maria Sakkari and Elise Mertens does she have more wins in her career in such events (seven each).
The final will mark the fourth meeting on clay between Swiatek and Sabalenka as world number one and two, equalling Chris Evert and Martina Navratilova for the most meetings on the surface as the WTA's top-two ranked players.
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