Bruno Fernandes has tested positive for COVID-19 and could miss Manchester United's crucial Champions League home clash with Atletico Madrid.
The playmaker missed Saturday's 3-2 win over Tottenham at Old Trafford, with his absence put down to an undisclosed illness.
Details have now emerged from interim manager Ralf Rangnick, who said Fernandes faced a race against time to be ready for the last-16 second leg on Tuesday.
Luke Shaw could be back from a coronavirus lay-off, while Rangnick is hopeful midfielder Scott McTominay will be able to feature after a calf problem.
Speaking of Fernandes, Rangnick said: "I don't know. With Scotty, I hope so, but he had some muscular problems with his calf. That's why we decided not to play him [against Tottenham], because Scotty, quite like Fred, is only valuable if he can perform with 100 per cent of his physical capacity.
"Luke hopefully will be back in training Monday and Bruno we will have to wait and see until Tuesday. This will probably be a last-minute race with him – due to COVID."
Fernandes has been United's chief creative force in the Champions League this season, with his six assists putting him four ahead of Shaw, who is second on that list at the club. He has also created a team-high 20 chances in the competition, with Cristiano Ronaldo next with nine.
Ronaldo's hat-trick against Tottenham has raised hopes that he can make a telling difference in Europe, too, with United level at 1-1 with Atletico after the first leg in Spain.
Rangnick said of his 37-year-old superstar striker: "He can be a leader with a performance like that. This is what I have been telling him since I arrived, that with this kind of performance he can be one of the engines of the team.
"We have quite a few other players who can do the same, including Fred, Harry [Maguire], Rapha [Raphael Varane], Victor [Lindelof], whoever. Even Edi [Edinson Cavani], when he came on, the last 10 or 15 minutes showed how important and what kind of role he can still play. I wish him to be available until the end of the season."
Rangnick was pleased with Jadon Sancho against Tottenham, with a notable assist for Ronaldo's second goal reflecting the winger's growing influence.
Sancho arrived with a big reputation from Borussia Dortmund last year and the 21-year-old did not immediately make the expected impact, but he is beginning to catch the eye.
"This is what he should be," said Rangnick, quoted on United's official website. "The club paid quite a few pounds for him in order to lure him away from Borussia Dortmund and if you pay that amount of money in a transfer fee for a player, he should perform on this kind of level.
"At the end, they are all human beings. The mere fact he cost a lot of money does not mean that he is playing at that level to start with.
"He told me that of course it was a problem for him to get adjusted to the intensity of the league, to the physicality of the league. Now he has managed to do that. I'm happy to see him play at that kind of level right now."
Atalanta not favourites for Coppa Italia final against Juventus, insists Gasperini
Atalanta do not consider themselves favourites for Wednesday's Coppa Italia final against Juventus despite their strong form, says coach Gian Piero Gasperini.
Atalanta have enjoyed a fantastic season, reaching the Europa League final – where they will face unbeaten Bundesliga champions Bayer Leverkusen on May 22 – and the Coppa Italia showpiece.
La Dea are also in the driving seat to secure Italy's fifth Champions League place for next season, after Sunday's 2-1 home win over Roma took them three points clear of the Giallorossi with a game in hand.
On Wednesday, an out-of-form Juve side await Atalanta at the Stadio Olimpico, as Gasperini seeks his first trophy with the club he joined back in 2016.
"I think it's a bit much to suggest we'd be favourites against Juve. We are in good form, but it's difficult to tell playing every three days," Gasperini told DAZN on Sunday.
"Naturally, we go into this Coppa Italia final with great enthusiasm."
Atalanta's Milan loanee Charles De Ketelaere produced another fine performance against Roma, scoring twice inside 20 minutes.
With 13 goals and nine assists, he is one of three Atalanta players to record 22 goal involvements in all competitions this season, alongside Gianluca Scamacca (17 goals, five assists) and Teun Koopmeiners (15 goals, seven assists).
Manchester City and Leverkusen (four apiece) are the only teams in Europe's top five leagues with more players with at least 22 direct goal involvements.
"Everyone knew he could play, or Milan would not have made an investment like that. He deserves the credit, he was going all over the place, right, left and centre tonight," Gasperini said of De Ketelaere.
Lorenzo Pellegrini reduced the deficit for the visitors with a penalty after 66 minutes, but overall Atalanta were dominant.
While Gasperini was happy with the win, he did not enjoy the wastefulness of his side.
"I don't know if we've learned a lesson, other than we had so many scoring opportunities and did not aim properly, otherwise we would have killed it off a lot earlier," he said.
"Failing to win this match really would have caused us a lot of problems."
Vilahamn wants to use FA Cup final defeat as 'beginning' for Tottenham Women
Tottenham Women manager Robert Vilahamn believes his side will use their FA Cup final defeat to start something special, rather than ending their good work.
Spurs were hammered 4-0 by Manchester United Women in Sunday's Wembley Stadium showpiece as Ella Toone and Rachel Williams were on target before Lucia Garcia's second-half double.
Vilahamn's side failed to manage a shot on target but the Spurs boss suggested his team will catch up to the women's elite clubs.
"The main thing I said was this is not the end, it is the beginning," Vilahamn said.
"We still have a gap between us and the top teams but that's normal. We are closing the gap but we haven't closed the gap yet."
Tottenham finished sixth in the Women's Super League as well as reaching this final, their first FA Cup showpiece appearance in their short history.
Vilahamn wants his Spurs players to use this defeat as motivation going forward.
"If you take away the feelings right now, you need to look at these players doing some incredible things this year," he said.
"We are at Wembley playing in front of our fans and they are actually enjoying it and staying, and supporting us after.
"We got a good experience today and we are learning how to play at Wembley more times. We need to look at it that way because the players are amazing."
'Not a good sign' – Keane unimpressed by Man Utd's injured absentees
Roy Keane was left questioning the attitudes of Manchester United's players as the Red Devils were once again without numerous key players for Sunday's loss to Arsenal.
Bruno Fernandes, Marcus Rashford and Lisandro Martinez were among the notable names to miss out for the 1-0 defeat at Old Trafford, as Erik ten Hag bemoaned continued injury issues.
Martinez and Harry Maguire's absence ensured Ten Hag had to field Jonny Evans and makeshift centre-back partner Casemiro in defence, with the latter at fault for Leandro Trossard's winning goal.
Wayne Rooney vocalised his concerns over the application of United's players and Keane, speaking on Sky Sports, echoed his thoughts as he questioned the prolonged absence of some.
"Obviously, that's not a good sign," Keane said of players not returning from injury. "You'd hope players who are carrying injuries are desperate to get back playing again.
"There is always a worry, there are always players at every club that can drag their heels with an injury.
"Generally, players I played with when they were given a period they'd be injured for, they were always trying to knock a week off it and get back playing for Manchester United or whatever club they're at."
Without a host of key players, United have conceded in 10 successive games in all competitions for the first time since October 2021.
The Red Devils' 82 goals they have conceded this season is their most since 1970-71 (also 82), too, as United continue to disappoint in the 2023-23 campaign.
United have also lost 19 games in all competitions this season, their most since 1977-78 (also 19), while their nine defeats at Old Trafford this term are their joint-most at home in a single campaign.
Keane says the concerns over players not racing back to fitness is not unusual, though it does little to aid Ten Hag's plight.
"It's always a worry but I have to say, it goes on at lots of football clubs," the United great said.
"There are lots of players out there when they have an injury, they're not in the hurry to get back in the team. I think that's obvious and happens at lots of football clubs."
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