Manchester City face a battle to retain their Champions League crown after being held to a thrilling 3-3 draw by Real Madrid in the Spanish capital.
The holders twice led in an enthralling contest under the Bernabeu Stadium’s new roof but the quarter-final remains on a knife edge after Federico Valverde gave the hosts a deserved share of the spoils.
Bernardo Silva got City off to a flying start but a Ruben Dias own goal and Rodrygo effort sent Real in at half-time of Tuesday’s first leg 2-1 ahead.
Phil Foden equalised for City with a brilliant strike and Josko Gvardiol put them back in front but Valverde had the final word to set up another intriguing contest at Etihad Stadium next week.
City missed the creativity and influence of Kevin De Bruyne who, having been feeling unwell, was sick soon after the team arrived at the stadium.
That forced manager Pep Guardiola to make a late change to his plans and bring Mateo Kovacic into the starting line-up.
The visitors initially seemed unaffected both by that and the raucous atmosphere Real had attempted to amplify by closing the roof at their newly-remodelled 85,000-capacity arena.
They were quickly onto the front foot and were given their early chance to take the lead when Aurelien Tchouameni crudely halted Jack Grealish to earn a booking that will keep him out of the second leg.
With Real failing to form a wall, Silva took full advantage and caught goalkeeper Andriy Lunin napping as he thumped a left-foot shot into the bottom corner after just two minutes.
City went close to adding a second as Erling Haaland had a shot saved from a tight angle and Grealish’s follow-up effort was blocked.
It had seemed the perfect start for City but Real hit back with two quickfire goals.
The equaliser came after a patient build-up as Eduardo Camavinga charged forward and fired a long-range shot that took a wicked deflection off Dias and gave Stefan Ortega – starting despite Ederson’s presence on the bench – no chance.
The hosts grabbed the lead just moments later as Rodrygo broke clear down the left and outpaced the backtracking Manuel Akanji before delicately poking the ball past Ortega.
Real threatened again as Valverde shot at Ortega and Rodrygo put another effort over.
City began to get sloppy in possession as Real upped the pressure. The normally solid Rodri looked laboured and Vinicius Junior tested Ortega before the break.
Grealish cut inside but missed the target as City tried to re-establish themselves early in the second half but Real regained control with Jude Bellingham and Vinicius going close.
Lesser sides could have folded but City underlined their enduring class as they not only weathered the storm but pulled themselves back into the game with a stunning strike from Foden.
The England international, who had been enduring a frustrating game, caught Lunin unaware as he lashed a ferocious strike into the top corner from outside the area after 66 minutes.
It was soon to get better for City as Gvardiol bagged his first goal for the club with an equally thunderous long-range effort five minutes later.
Yet, in keeping with a compelling encounter, it was not to be the end of the scoring as Real responded yet again.
This time Valverde was the player on target as he met a Vinicius cross with a fine volley that flew past Ortega.
Simeone insists Atletico 'cannot stop pushing' after narrow Mallorca win
Diego Simeone insists Atletico Madrid "cannot stop pushing" in their pursuit of Champions League qualification after a narrow 1-0 victory over Mallorca.
Los Rojiblancos tightened their grip on fourth place in LaLiga, with Rodrigo Riquelme's fine individual effort in the fifth minute enough to secure back-to-back wins.
With four games remaining, Simeone's side moved onto 67 points, six clear of fifth-placed Athletic Bilbao, who they beat 3-1 last weekend.
The Atleti boss was thrilled by his players' performance levels, but has urged them not to rest on their laurels.
"The team interpreted the plan very well," he said. "The commitment was incredible from [Angel] Correa to [Jan] Oblak to play an intelligent game from a defensive point of view.
"After the goal, we controlled the game. We defended as a team and did a great job. We need to continue improving, and we can't stop pushing until the season is over."
Echoing his manager's thoughts, defender Axel Witsel told Movistar Plus+: "It was very important to win. We wanted to win and stay six points ahead. We have to keep it up.
"After Riquelme scored a fantastic goal, we managed to stay well-organised to secure the result."
'It hurts to lose' - Inzaghi apologises after Sassuolo defeat
Simone Inzaghi admits "it hurts to lose" following Inter's surprise 1-0 defeat by relegation-threatened Sassuolo.
The newly crowned Scudetto winners suffered only their second loss of the season in Serie A, as Armand Lauriente's first-half goal was enough to give the 19th-place hosts victory at Mapei Stadium.
Sassuolo, who boosted their survival hopes, subsequently completed the league double over the Nerazzurri, having also prevailed 2-1 at San Siro in September.
Meanwhile, Inter were beaten by a team in the bottom two for the first time since November 2014, with Inzaghi urging his players not to be distracted by their title triumph.
"We started sluggish and didn’t have the right approach to the game," he told Sky Sports Italia. "I'm sorry for the defeat, but credit must be given to Sassuolo for a performance of great effort and sacrifice.
"It's right to enjoy [our Scudetto victory], but there are still three games to go and we have to focus. It hurts to lose, and it should hurt."
After guiding Inter to their 20th Serie A crown, Inzaghi is hopeful he can keep the majority of his squad intact ahead of next season.
However, the Nerazzurri boss did emphasise the club's need to strengthen before launching their Scudetto defence.
"I already told the club that I want to go into next season with all the players I had this term, not losing a single one," he said. "Considering all the games we need to play and the length of the season, we do need a bigger squad."
Inter Miami 6-2 New York Red Bulls: Messi makes more MLS history as Suarez scores hat-trick
Lionel Messi had a hand in all six goals while Luis Suarez scored a hat-trick as Inter Miami overcame the New York Red Bulls 6-2 at Chase Stadium.
The Eastern Conference leaders were on a three-match winning streak in MLS, but fell behind to Dante Vanzeir's opener in the 30th minute.
However, the hosts turned the match on its head after the break, with Messi assisting a brace for half-time substitute Matias Rojas either side of getting on the scoresheet himself.
Suarez then took centre stage with a hat-trick inside 13 minutes - all assisted by his former Barcelona team-mate - while Emil Forsberg's stoppage-time penalty was a mere consolation for the visitors, who are now without a win in four.
Data debrief
Messi broke two more MLS records following yet another inspirational display for the Herons.
The eight-time Ballon d'Or winner's six goal contributions and five assists were both the most recorded by a player in a single game.
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