Spezia and Hellas Verona face a relegation play-off following a dramatic final day of the Serie A season.
The two sides started the day level on points and could not be separated after both suffered defeats away from home.
Dimitris Nikolaou gave Spezia the lead against Europa League runners-up Roma after just six minutes, but Nicola Zalewski equalised just before half-time and Paulo Dybala held his nerve to convert a 90th-minute penalty.
The spot-kick was awarded after Kelvin Amian fouled Stephan El Shaarawy, with Amian sent off for a second bookable offence.
Verona were on course for the point against AC Milan which would have been enough for safety when Davide Faraoni’s 72nd-minute goal cancelled out Olivier Giroud’s penalty, but Rafael Leao scored twice in the closing minutes to give the Rossoneri a 3-1 win.
After the match, Milan striker Zlatan Ibrahimovic announced his retirement from football at the age of 41.
The first relegation play-off since Bologna faced Parma in 2005 will take place at a neutral venue next weekend.
At the other end of the table, Atalanta thrashed 10-man Monza 5-2 to secure a Europa League place along with Roma, with Juventus set for the Europa Conference League despite a 1-0 win at Udinese.
Champions Napoli ended the season with a 2-0 win over bottom side Sampdoria, Victor Osimhen scoring his 26th goal of the season from the penalty spot after being fouled in the area and Giovanni Simeone rifling home from distance five minutes from time.
A potentially dramatic battle in LaLiga failed to produce any real fireworks as Real Valladolid were relegated following a 0-0 home draw with Getafe.
Six teams were in danger of joining the already-relegated Espanyol and Elche in going down, but Valladolid started and ended the day in the bottom three following a disappointing stalemate.
Celta Vigo made certain of survival with a 2-1 win over champions Barcelona thanks to a brace from Gabri Veiga.
Barcelona ended the season 10 points clear of runners-up Real Madrid after Karim Benzema marked his final appearance for the capital club with the equaliser in a 1-1 draw with Athletic Bilbao.
Benzema scored a 72nd-minute penalty to cancel out Oihan Sancet’s opener early in the second half.
In Belgium, Toby Alderweireld fired in a stunning last-gasp goal to help Royal Antwerp win their first league title since 1957.
The former Tottenham defender – who joined his hometown club last summer – equalised in the fourth minute of stoppage time from outside the box as Antwerp rescued a 2-2 draw against title rivals Genk.
The goal meant Antwerp edged out both Genk and Union Saint-Gilloise by just one point to win the Belgian league title for only the fifth time in their history.
Fiorentina 2-2 Napoli: Kvaratskhelia keeps visitors' slim European hopes alive
Dethroned Italian champions Napoli's hopes of playing European football next season are hanging by a thread after they played out a 2-2 draw at Fiorentina in Serie A on Friday.
Napoli took the lead in the eighth minute through defender Amir Rrahmani, who nodded home a corner by Matteo Politano.
Cristiano Biraghi levelled for Fiorentina in the 40th minute from a free-kick, before M'Bala Nzola put the hosts in front two minutes later when he fired a shot into the bottom corner of the net.
Napoli's Khvicha Kvaratskhelia responded with another stunning free-kick early in the second half to rescue a point for his team.
Eighth-placed Fiorentina, on 54 points and with a game in hand, are five points behind Lazio in seventh.
They can still earn a Europa League spot either by leapfrogging the Rome side or by winning the Europa Conference League final in which they face Greece's Olympiakos on May 29.
Ninth-placed Napoli, on 52 points, still have a slim chance of making the Europa Conference League playoffs.
Data Debrief
Fiorentina left-back Biraghi has now scored six goals from direct free-kicks since the start of 2021-22, which is behind only James Ward-Prowse (seven) - now of West Ham and formerly of Southampton - as the most across Europe's top five leagues in that period.
Kvaratskhelia also levelled via a direct free-kick, making this the first Serie A match in which both teams scored via that route since Fiorentina against Lazio in April 2018 (Jordan Veretout and Luis Alberto in that case).
Southampton 3-1 West Brom (3-1 agg): Saints set up play-off final with Leeds United
Southampton saw off West Brom 3-1 at St Mary's on Friday to set up a Championship play-off final showdown with Leeds United.
Leeds thumped Norwich City 4-0 at Elland Road 24 hours earlier to book their place at Wembley, where Southampton now await on May 26.
The first leg between the Saints and West Brom finished goalless - just like the other semi-final - but the home side's quality told in the end.
Russell Martin's side dominated the first-half possession, with David Brooks going closest to scoring with a shot that hit the outside of the post.
Southampton made the breakthrough via a powerful Will Smallbone finish four minutes into the second half after Gray Diangana lost possession.
Darnell Furlong had a shot helped over by Alex McCarthy, while David Brooks - who assisted the opener - had a strong penalty appeal rejected.
Southampton remained in control, though, and Adam Armstrong scored a second with a shot through Furlong's legs and past Alex Palmer.
Armstrong's second goal arrived from the penalty spot in the 86th minute after Tom Fellows fouled Ryan Manning in the box, rendering Cedric Kipre's late header a mere consolation.
Marc Skinner signs Manchester United Women contract extension
Marc Skinner has signed a one-year contract extension as Manchester United Women head coach with the option of a further 12 months.
The 41-year-old guided United to their first major silverware last weekend with victory over Tottenham in the Women's FA Cup final.
United are fifth in the Women's Super League with one game to go - a massive drop on last term's runners-up finish - but Skinner will stay on.
"It's an honour to extend my stay at Manchester United," Skinner, who was appointed in 2021, told United's official website after the news was confirmed on Friday.
"I've always felt at home here, with our excellent players, staff, and fans.
"Being able to secure the team's first major trophy at Wembley was a real career highlight for me and another sign of our continued growth, on and off the field."
United conclude their campaign on Saturday against Chelsea, who lead Manchester City on goal difference entering the final day.
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