It's fair to say Serie A sides have enjoyed themselves on the continental stage this season, with six Italian clubs reaching major European quarter-finals for the first time this century.
Three of those teams have been making waves in the Champions League, for which Luciano Spalletti's Napoli have been touted as genuine contenders after outscoring every other team in the competition.
Meanwhile, rivals Milan and Inter went about their last-16 assignments in quietly impressive fashion, seeing off Tottenham and Porto respectively, both winning 1-0 on aggregate.
With three of Italy's finest reaching the last eight, a first all-Italian Champions League meeting since 2005 was always highly probable, and so it proved with Milan and Napoli paired together.
With the winner of that tie set to face either Inter or Benfica in the semi-finals, the prospect of a first Italian Champions League winner since Inter's class of 2009-10 has perhaps never appeared more realistic.
Ahead of a blockbuster tie between last season's Serie A winners and their likely successors, Stats Perform looks back at the Champions League's previous all-Italian tussles.
Shevchenko decisive in tight derby double-header
Given the remarkable European pedigree enjoyed by seven-time European Cup/Champions League winners Milan, the fact that the Rossoneri have featured in all five previous all-Italian games in the competition is perhaps unsurprising.
The first two of those came at the semi-final stage in the 2002-03 campaign, when Milan and Inter faced off in a tense double-header ultimately decided by a Rossoneri great.
Milan had reached the last four courtesy of Jon Dahl Tomasson's last-gasp strike against Ajax, while the Nerazzurri edged out Valencia on away goals.
Hector Cuper's men had less luck with that rule against their rivals, with Andriy Shevchenko's 'away' goal deciding a tie which ended 1-1 on aggregate – despite, of course, both legs being held at San Siro.
Inter's Obafemi Martins set up a tense finish after coming on as a substitute, but Carlo Ancelotti's team held on to reach a first final since 1995 – where they would face another domestic rival.
Dida wins battle of the goalkeepers at Old Trafford
Italian football's reputation for being risk-averse has not always been warranted, but given the way 2003's Champions League final between Milan and Juventus played out, that tag is perhaps understandable.
Juve had already edged out both Milan giants to win Serie A by the time they faced the Rossoneri at Old Trafford, for what represented Marcello Lippi's fourth Champions League final with the Bianconeri (winning in 1996, losing in 1997, 1998 and 2003).
Both defences were on top throughout a nail-biting affair, with Shevchenko seeing a goal ruled out for offside and Antonio Conte rattling the crossbar as the game went to a penalty shoot-out.
With both goalkeepers clearly advancing off the goal line for each spot-kick, Gianluigi Buffon saved from Clarence Seedorf and Kakha Kaladze – only for Dida to go one better by denying David Trezeguet, Marcelo Zalayeta and Paolo Montero as Milan won their sixth European crown.
Dida in the spotlight again as violent scenes mar San Siro clash
Dida was again in the spotlight when two Italian sides last squared off in the Champions League – this time for all the wrong reasons.
The 2004-05 quarter-finals featured another heavyweight derby clash between Milan and Inter – who, as was the case two years earlier – finished the Serie A season in second and third respectively as Juventus triumphed.
Milan have always been Italy's European kings, however, and goals from Jaap Stam and Shevchenko put them in the ascendency as Ancelotti's men won the 'home' leg 2-0.
When Shevchenko's first-half effort put the Rossoneri ahead in the return game and Inter – now requiring four goals – saw an Esteban Cambiasso strike ruled out for a foul, the Nerazzurri supporters reacted furiously.
Flares rained down from the stands onto the San Siro pitch, with Dida struck on the shoulder and left requiring treatment for a burn.
Referee Markus Merk attempted to restart the game after a lengthy delay, but when Christian Abbiati was targeted with further missiles, the game was abandoned and Milan were awarded a 3-0 win, making it 5-0 on aggregate and leading to condemnation from across the continent.
From a Milan point of view, the less said about their subsequent trip to Istanbul for the 2005 final against Liverpool, the better.
Hayes concedes title race is over as Chelsea suffer dramatic Liverpool defeat
It has been a difficult week for Chelsea and their boss Emma Hayes.
After seeing their Champions League dreams dashed by holders Barcelona on Saturday, they had no margin for error when they travelled to Liverpool in the Women's Super League on Wednesday.
Six points behind Manchester City with two games in hand but an inferior goal difference, the Blues needed three points to stop Hayes' final season in charge from totalling unravelling.
But there was to be no respite for the Blues, who were at one point tipped for a quadruple but have been stuck in a downward spiral since losing Sam Kerr to an anterior cruciate ligament injury during the winter break.
Matt Beard's Liverpool put on a tremendous display to win 4-3, with Gemma Bonner scoring a stoppage-time equaliser to leave Hayes certain the title is out of reach.
"I think the title is done," she said after Wednesday's game.
"Of course mathematically it's not, but I think the title is done. Our job between now and the end of the season is to keep pushing until the end, but I think it will be very difficult.
"This team has done a tremendous job in my time here to push for titles.
"I don’t know if we have ever conceded four goals in a half before. Three from set pieces is just unforgivable. But I'm going to credit Liverpool."
Chelsea now need an almighty collapse from City, who may only require three points from their remaining two matches to seal the title, if their goal difference advantage holds firm.
Hayes believes fighting on multiple fronts has not helped her team, adding: "We looked exhausted but I don't want to make excuses.
"I want to remind our fans how much success we have brought over the years. It's just not to be this year."
Next up, Chelsea face relegated Bristol City in their final home game before Hayes departs to take the United States job, with City taking on Arsenal in Sunday's headline fixture.
Sancho outshines Mbappe as Dortmund seize initiative against PSG
Manchester United loanee Jadon Sancho issued a reminder of his star quality as Borussia Dortmund beat Paris Saint-Germain 1-0 in the first leg of their Champions League semi-final tie on Wednesday.
Niclas Fullkrug scored the winner after 36 minutes, taking in Nico Schlotterbeck's floated pass before driving a low shot beyond PSG goalkeeper Gianluigi Donnarumma.
Fullkrug has now been involved in six Champions League goals this season (three goals, three assists), the joint-most by a German player in their debut campaign in the competition, alongside BVB team-mate Marco Reus in 2012-13 (four goals, two assists).
The star of the show, however, was undoubtedly Sancho.
He tormented Nuno Mendes throughout a lively performance, creating three chances for his team-mates – a game-high tally alongside Julian Brandt, Kylian Mbappe and Achraf Hakimi.
Sancho had completed seven dribbles by the halfway point, more than he managed in any full game for the Red Devils.
By full-time, that number had crept up to 12, the most by any player in a Champions League semi-final since Lionel Messi completed 16 for Barcelona against United in April 2008, and the most on record by an Englishman at any stage of the competition (since 2003-04).
Sancho even outshone Mbappe, who struck the far post with a curling effort early in the second half but was limited to just three shots totalling 0.17 expected goals (xG).
PSG did have their chances, though, with their total of 14 shots their most without scoring in any Champions League game since the second leg of their 2020-21 semi-final against Manchester City (also 14), when they were beaten 2-0 and eliminated from the competition.
Dortmund are now unbeaten in 11 straight Champions League home games, winning seven and drawing four.
It's their longest ever such streak at Signal Iduna Park, and they have also won four straight knockout games on their own turf for the first time in their Champions League history.
While Dortmund have a valuable lead to protect in Paris next Tuesday, Edin Terzic will be expecting a strong reaction from PSG.
The Ligue 1 champions have progressed from two of their last four Champions League knockout ties when losing the first leg, with the first of those successes coming against Dortmund in the last 16 in 2019-20 (1-2 away, 2-0 at home).
Borussia Dortmund 1-0 Paris Saint-Germain: Fullkrug hands hosts first-leg win
Niclas Fullkrug fired home a first-half winner as Borussia Dortmund claimed a 1-0 victory over Paris Saint-Germain in the first leg of their Champions League semi-final tie in Germany.
Nico Schlotterbeck floated a pass into Fullkrug's path and the Germany international brought the ball under his spell with a wonderful touch before drilling a low shot past Gianluigi Donnarumma in the 36th minute.
PSG, on the back foot for much of the first half, improved after the break and struck the woodwork twice in a matter of moments just after the restart.
Kylian Mbappe curled an effort against the right-hand post before Achraf Hakimi scuffed a shot against the other upright on the rebound as Edin Terzic's side escaped with a first-leg lead.
The teams will meet again at the Parc des Princes next Tuesday, with the winners of the tie facing either Bayern Munich or Real Madrid – who drew 2-2 in their first leg on Tuesday – in the final at Wembley Stadium.
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