Chelsea continued their frustrating start to the Premier League season with a disappointing loss at Southampton – which had previously been a happy hunting ground.
The Blues took an early lead but could not hold off a Southampton comeback, leaving Thomas Tuchel's side with just two wins from their opening five league games.
Brighton and Hove Albion's unbeaten start came to an end against Fulham at Craven Cottage, Crystal Palace conceded a late equaliser against Brentford, while Leeds United and Everton shared the spoils in a fiery 1-1 draw at Elland Road.
Here, Stats Perform unpacks the pick of the data from Tuesday's fixtures in the English top flight.
Southampton 2-1 Chelsea: Sterling delivers but Saints finally sink Blues at home
Romeo Lavia and Adam Armstrong cancelled out Raheem Sterling's opener as Southampton beat Chelsea at home in the Premier League for the first time since March 2013.
Saints were winless in nine games at St Mary's against Chelsea in the competition and would have feared a familiar fate after Sterling poked home in the 23rd minute.
That marked the forward's 169th goal involvement (112 goals, 57 assists) in the top flight, a tally bettered by only Harry Kane (230) Sergio Aguero (209 and Jamie Vardy (175) since Sterling made his debut in March 2012.
But Lavia soon hit back as he became the fourth youngest Southampton player to score in the Premier League, with the recent arrival aged just 18 years and 236 days.
A smart Armstrong finish then inflicted consecutive top-flight away defeats on Chelsea for the first time under Tuchel, who may have reasons for concern after an underwhelming start to the new campaign.
Indeed, Chelsea (W2 D1 L2) have lost two or more of their first five games in a Premier League season for just the second time this century. The last time it happened, they finished 10th in 2015-16 after opening with three losses in five games.
Fulham 2-1 Brighton and Hove Albion: Mitrovic ends Seagulls' flying start
Brighton headed to Craven Cottage unbeaten in nine league games, winning six of those, but were undone by Aleksandar Mitrovic and a Lewis Dunk own goal.
Mitrovic continued his fine form in front of goal for his 48th-minute opener, scoring for a fourth time in the Premier League against the Seagulls, more than he has managed against any other side in the competition.
The Serbian's strike also marked his 100th league goal in Fulham colours before Dunk turned into his own net – his sixth Premier League own goal, more than any other player since the start of the 2016-17 season.
Richard Dunne (10), Martin Skrtel (7), Phil Jagielka (7) and Jamie Carragher (7) are the only players to find their own net more in Premier League history than Dunk, who endured a night to forget.
Alexis Mac Allister offered brief hope of sparing Dunk's blushes with a penalty, but Fulham held on to reach eight points from five games, their best start to a top-flight season since the 2012-13 term (nine points).
Crystal Palace 1-1 Brentford: Zaha-reliant Eagles suffer more London derby frustration
Wilfried Zaha continued to carry the hopes of Selhurst Park on his shoulders, but his curling effort was not enough to see Palace to a rare London derby victory.
The Ivory Coast international found the top-right corner in the 59th minute to open the scoring, his 13th goal in 20 appearances in the Premier League in 2022, as many as he managed in his previous 45 games in the competition.
Zaha has also scored six of Palace’s last seven home league goals, but the Eagles could not hold out for what would have been just a third win in their last 20 top-flight London derbies.
Yoane Wissa denied Palace in the 88th minute with a fourth league goal in his last eight games on the road.
Brentford have now avoided defeat in five of their last eight Premier League games where they conceded first (W2 D3 L3), while Palace have won just one of their last five when opening the scoring in the league.
Leeds 1-1 Everton: Lampard's men let another lead slip
Everton remain winless this season in the Premier League (D3 L2), despite taking the lead at Elland Road through Anthony Gordon. Expecting Everton to hold a lead has become a fool's game.
Luis Sinisterra's leveller means that since Frank Lampard's first league game in charge of Everton in February, only Leicester (16) and Wolves (14) have dropped more points from winning positions than the Toffees (13).
Leeds would have seen this as an opportunity to put three more points on the board, but at least their unbeaten run at home continues. They have earned eight points from their last four league games at Elland Road (W2 D2), which is as many as they had mustered from their previous 11 (W2 D2 L7).
Will Gordon stay with Everton beyond Thursday's transfer deadline, or could the links to Chelsea see him move on? He has now scored two goals in his last two Premier League games, having netted just four in his first 52 appearances. His last two strikes have been away from home, with each of his first four coming at Goodison Park.
Inter Miami 1-0 D.C. United: Super-sub Campana seals late win
Inter Miami snatched a 1-0 win over D.C. United thanks to Leonardo Campana’s stoppage-time strike.
Campana had an instant impact after coming on in the 93rd minute as he volleyed in the winner just 25 seconds later.
Lionel Messi returned from a knee injury that kept him out against Orlando City but struggled to have his usual impact as Miami only managed eight shots.
Cristian Dajome had come closest to scoring for D.C. minutes after his introduction, but his dipping shot sailed over the bar.
Miami remain a point clear of FC Cincinnati at the top of the Eastern Conference, while D.C. sit ninth, a huge 14 points behind the league leaders.
Data Debrief: Miami continue to set the pace
Miami left it late to get back to winning ways but extended their unbeaten run to nine games. It is their longest run without defeat in the competition.
D.C. have now conceded eight goals in the last 15 minutes of the second half - only Montreal (10) and San Jose Earthquakes (10) have conceded more in that time in the MLS this season.
Montero to coach Juventus until end of the season
Paolo Montero will take charge of Serie A side Juventus for the remainder of the season following the dismissal of Massimiliano Allegri.
Juventus sacked their former head coach Allegri on Friday over his behaviour during and after this week's Coppa Italia final in which he was sent off, ending a long period of speculation over his future.
Montero, who coaches Juventus' Under-19s team, will take charge for their remaining two matches, at Bologna on Monday and against Monza at home on May 26.
The 52-year-old Uruguayan won four Serie A titles playing for Juventus as a defender from 1996 to 2005 and will take his first training session on Sunday.
"Paolo is a Juventus legend, firstly on the pitch, and someone who has long been a bearer of the club's DNA on the bench," Juve said in a statement.
"Best of luck, Paolo!"
Juve are assured of Champions League qualification but could still finish between third and fifth in Serie A this season.
Emery admits 'I have my dreams' with Villa after sealing Champions League qualification
Unai Emery has his sights set on winning the Premier League or Champions League with Aston Villa after securing a top-four finish earlier this week.
Fifth-place Tottenham's defeat to title-chasing Manchester City on Tuesday meant Villa will play in Europe's premier club competition next season for the first time in 41 years.
Emery's side conclude a memorable season – in which they also reached the Europa Conference League semi-finals – away at Crystal Palace on the final day.
And the Spaniard is already focused on achieving bigger and better things with Villa.
"It really was amazing when the [Tottenham-Manchester City] match finished," he smiled. "At the beginning of the season, it was really a dream. Of course, we worked hard to try to be there.
"I want to get better, and I have my dreams, and I believe in my dreams. Of course, my objectives are to win the Premier League or the Champions League. We are not contenders, but it is our dream to achieve something like that."
Meanwhile, Palace have enjoyed a strong finish to the season, winning five of their last six games.
The Eagles could seal a top-half finish with a victory – and other results going their way – and Oliver Glasner has urged his players to use that as inspiration at Selhurst Park.
"I'm pleased with the performances we've had," he said. "We want to win. We always focus on what we can influence. If we don't do our job, we don't win, we can't be 10th. It's good motivation at home to say thank you to the fans."
PLAYERS TO WATCH
Crystal Palace – Jean-Philippe Mateta
Mateta has scored in each of his last six home Premier League appearances for Palace, netting eight goals along the way.
He is now aiming to become only the second Frenchman after Thierry Henry to find the net in seven successive Premier League appearances on home soil.
Aston Villa – Ollie Watkins
Watkins has recorded the most assists in the Premier League this season with 13.
Only Ashley Young has ever provided more during a single Premier League campaign for Villa (14 in 2007-08).
MATCH PREDICTION: DRAW
Palace are unbeaten on each of the previous 11 occasions they have finished a top-flight season with a home match (winning seven, drawing four).
By contrast, Villa have only won once in the 25 occasions they have finished a league campaign with an away game (drawn seven, lost 17).
That sole victory came against Chelsea at Stamford Bridge in 2001-02.
On a brighter note, Villa are unbeaten in their last 10 Premier League away games in London, winning five of their six this term.
With 16 such points this season, a win or draw here would set a new Premier League record for the most achieved during a single campaign.
Although, you must go back to their title-winning season of 1980-81 for the last time they completed a league double over Palace.
OPTA WIN PROBABILITY
Crystal Palace: 31.8%
Aston Villa: 39.5%
Draw: 28.7
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