Josh Allen vowed the Buffalo Bills will be better for their stunning loss to the Jacksonville Jaguars, for which he placed the blame on his shoulders.

The Bills were heavy favourites to move to 6-2 against a Jaguars team that came into the game 1-7 and without a win in the United States since Week 1 of last season.

But Allen and the Bills' offense were stifled by a superb performance from a much-maligned Jaguars defense as Jacksonville claimed a remarkable 9-6 win.

Allen was part of an unwanted piece of history for the Bills quarterback, who saw Jaguars defensive end Josh Allen sack him, intercept a pass and recover one of his fumbles.

It was the first time any such plays had taken place between two players with the same name.

And Allen felt the Jaguars and his namesake were worthy of the victory in a game in which he was sacked four times and intercepted twice.

"Credit to them, they wanted it more. I put the ball in danger too often, bit us in the butt," Allen told a media conference. 

"We played like s*** and it starts with me. This loss stings, but I'll tell you that this one makes the other games feel better, having this pit in our stomach right now puts things into perspective.

"It's a week-to-week league, any given Sunday any team can come out here and play well and beat the other team, that's just how it goes, it's life sometimes, we'll use this to our advantage, we'll be better from it.

"I don't want to lose, I don't want to lose games. I feel like I could have played better. I could have helped our team and put us in better situations, and I didn't.

"So, I'm frustrated with myself more so than anything. I gotta be better for this team."

Matthew Stafford's performance through his first eight games in a Los Angeles Rams uniform put him in the NFL MVP conversation, but Sunday felt more like the bad old days in Detroit for the veteran quarterback. 

Hounded throughout the game by the Tennessee Titans' defence, Stafford threw two critical interceptions as the Rams fell 28-16 at home.

The turning point of the game occurred early in the second quarter, when Stafford tried to throw the ball away while being pulled down by Jeffrey Simmons in the end zone. 

His blind heave landed in the arms of Titans linebacker David Long, who returned it to the two-yard line and set up a Tennessee touchdown on the next play. 

The Rams (7-2) got the ball back after the kick-off and Stafford took to the air again, trying to hit Robert Woods, but Titans defensive back Kevin Byard jumped it and went 24 yards for the Titans' second TD in 11 seconds. 

It was the 24th time Stafford had an interception returned for a touchdown, the most of any active NFL quarterback. 

"I mean, I basically spotted them 14 points," Stafford told reporters. "Can't do that in the NFL, especially against a good team like that that wants to get out in front, run the football, mix coverages, do all that kind of stuff. Just wasn't good enough early in the game.

"Turnovers really killed us and those are on me, so if I clean those up and I know I will, I've got a lot of confidence in this team to go out there and play some really good football."

Though Stafford could have made better decisions on both of those plays, Tennessee's defenders were flying around the field all game. 

The Rams had surrendered an NFL-low eight sacks through the first eight games, but the Titans (7-2) brought down Stafford five times on Sunday.

"Those guys played fantastic," Titans head coach Mike Vrabel said of his defence. "It was fun to watch them play. 

"We really think that group is playing with a lot of confidence right now. They would be able to come in here and play the way they did and hold them to field goals, and we played great in red zone."

Tennessee twice forced the Rams to settle for field goals in the red zone and did not surrender a touchdown until Stafford threw a three-yard pass to Sony Michel with 24 seconds to play in the game. 

It all added up to a winning formula for the Titans even as they managed just 194 yards of total offence while playing without their injured star Derrick Henry. 

"Those guys played some great ball defensively. It made up for our lack of offence," said veteran running back Adrian Peterson, who signed with Tennessee this week and scored his 125th career touchdown.

"You hear all this talk about the Rams' defence. What about the Titans' defence? Those guys came out and played outstanding."

Green Bay Packers head coach Matt LaFleur shouldered the blame for Jordan Love's struggles in the 13-7 defeat to the Kansas City Chiefs.

Love made his first start for the Packers after reigning NFL MVP Aaron Rodgers was left on the sidelines having tested positive for coronavirus on Wednesday.

The Rodgers-less Packers (7-2) fell short on Sunday with Love under centre in Kansas City, where Green Bay's seven-game winning streak came to an end.

Love – the 26th pick in the 2020 NFL Draft – was 19-of-34 passing for 190 yards, a touchdown and interception, while the 23-year-old rushed for another 23 yards on five carries.

"This one falls on me, squarely," LaFleur said when discussing Love's woes against the blitz. "Certainly, for us to be two for 12 on third down, obviously didn't have a good enough plan for some of the zero pressures that they brought on us.

"But I thought our guys battled. I thought Jordan, I was really proud of the way he played. He hung in there, he was taking hits and delivering the ball.

"I thought he did a really good job. But I think that, ultimately, I've got to be better and this one falls squarely on me."

Regarding his own performance, Love added: "Obviously not good enough. I think we started off a little slow, I started off a little slow personally.

"I think we got into a bit of a rhythm later. Obviously, it was too late. Just not good enough."

"I think we started having a better answer in the end, but yeah, they were bringing the all out, they were eating us up and we just weren't able to execute on those plays that we had against it," Love said.

"I think all it took was maybe one big play against it, and it wouldn't have been coming as much. Obviously, we weren't able to execute it, so that's why they kept bringing it."

Half a minute made all the difference as the Tennessee Titans' defence made two huge plays in quick succession to stun the Los Angeles Rams 28-16 in the NFL on Sunday.

Rams quarterback Matthew Stafford threw two interceptions in a 26-second span early in the second quarter, leading to a pair of rapid-fire Titans touchdowns. 

The first was an ill-advised attempt to throw the ball away while being dragged down in the end zone that David Long intercepted at the Rams' eight-yard line.

After Geoff Swaim scored on a two-yard TD pass from Titans QB Ryan Tannehill on the ensuing play, Stafford's next pass was picked off and returned 24 yards for a TD by Kevin Byard. 

Tannehill would run the ball in for another score prior to half-time as the Titans built a 21-3 lead before handing the game over to their ferocious defence, which sacked Stafford five times after LA entered the game with only eight sacks allowed all season. 

Titans recruit Adrian Peterson scored his 125th career TD, joining 11 other players to score 125-plus career touchdowns.

The Rams (7-2) would not find the end zone until Stafford hit Sony Michel for a short TD with 24 seconds remaining in the game as they fell behind the victorious Arizona Cardinals (8-1) in the division race. 

Tennessee (7-2) now hold the best record in the AFC despite being out-gained 347-194 as star running back Derrick Henry remains sidelined with a foot injury.

Tannehill completed 19 of 27 passes for just 143 yards with a TD and an interception but his 79.7 passer rating was still better than Stafford's 71.0 after the Rams QB finished 31-of-48 passing for 294 yards. 

DeSean Jackson appears set to join the Las Vegas Raiders. 

The Los Angeles Rams waived veteran wide receiver on Tuesday after the team could not move him before the NFL's trade deadline. 

Jackson posted a photo illustration of himself in a Raiders uniform to his Instagram account on Sunday, not long after long-time NFL reporter Josina Anderson said the three-time Pro Bowler told her he was joining Las Vegas. 

The 34-year-old, who signed a one-year deal in the offseason, caught eight of 15 passes for 221 yards and one touchdown in seven games for the Rams.

"I understand that everything happens for a reason and I look forward to beginning the next chapter of my NFL career," Jackson said after his release by LA.

The Raiders immediately emerged as a likely destination when they cut ties with receiver Henry Ruggs III this week after he was charged by police following a fatal car crash. 

Various injuries limited Jackson to eight total games over the previous two seasons in his second career stint with the Philadelphia Eagles. 

All three of his Pro-Bowl selections came in his first spell with the Eagles, as he had at least 900 yards receiving in five of his first six seasons in the league. 

Lamar Jackson revelled in another NFL record after leading the Baltimore Ravens to a 34-31 overtime win against the Minnesota Vikings.

Jackson posted his 12th career 100-yard rushing game (including playoffs) – a record for quarterbacks in the NFL – on Sunday.

The former MVP moved past four-time Pro Bowler Michael Vick, who achieved the feat in 11 games across his 13-year career.

Jackson, though, matched Vick in the regular season with his 10th 100-yard rushing game.

"Of course, I respect [Vick's] game. That's cool," Jackson said after rushing for 120 yards on 21 carries at home to the Vikings.

"I don't know what to say. That's pretty cool, though."

Jackson completed 27 of 41 passes for 266 yards, three touchdowns and two interceptions in Baltimore.

"We just had to do what we had to do to get the victory," Jackson said. "We just ran for a lot today. That's just what it was."

Jackson also registered his 22nd career 75-yard rushing game, surpassing Vick, while he tied Cam Newton for the most games with at least 250 passing yards and 100 rushing yards (three) in league history.

With his ninth career performance with at least 200 passing yards and 75 rushing yards, Jackson tied Russell Wilson for the most in NFL history, while his 15th consecutive game with a touchdown pass matched a franchise record he set in 2019-20.

"There are no long-term sustainability observations. That's not even relevant," Ravens head coach John Harbaugh when asked whether Jackson's running game was sustainable.

"Would you rather not run 21 times and lose the game? It's crazy to even suggest that."

The Dallas Cowboys managed to hold down the fort while Dak Prescott was sidelined with a calf strain, but everything fell apart as their quarterback returned to the line-up in Sunday's 30-16 loss to the Denver Broncos.

Prescott completed fewer than half of his pass attempts and could not lead Dallas to any points until the game was well out of reach in an emphatic home defeat against the Broncos that ended their six-game winning streak in the NFL.

Dallas turned the ball over on downs on their first two possessions and four times overall in the game, failing on all four of their fourth-down conversion attempts as they compiled a season-low 290 yards after averaging 454.9 entering the game.

"Frankly we were outcoached, we were outplayed all the way through," Dallas head coach Mike McCarthy told reporters. "This is the first time I've felt clearly our energy didn't exceed our opponent. That's disappointing."

The Cowboys had not trailed by double digits all season but found themselves down 30-0 by the time Prescott threw the first of two touchdown passes late in the fourth quarter.

Prescott entered the game leading the NFL with a 73.1 completion percentage but connected on just 19 of 39 attempts (48.7 per cent), matching the second-worst showing of his six-year NFL career. 

The Cowboys QB insisted he felt "fine" and there were no residual effects from the leg he injured on the game-winning touchdown pass three weeks earlier against the New England Patriots, but acknowledged he did not perform to his standards.

"I mean obviously I wasn't as clean as I normally am or as I have been. It's tough to say and blame that [injury]," Prescott said. "I'm not going to sit there and blame two weeks [off] when I had a great week of practice under my belt coming into this one.

"I just missed some throws and we weren't our normal selves in the passing game when we needed to be. We didn't execute…

"We got beat. We got thumped in every aspect of the game, especially on offence."

McCarthy could have been forgiven for pulling Prescott with the game out of reach in the fourth quarter, especially coming off an injury, but the quarterback said he never considered remaining on the sidelines no matter the margin. 

"There was game left out there to be played," Prescott said. "It never crossed my mind that I was coming out of the game. I think if somebody would have tried to make that decision, I would have told them I wasn't.

"We needed to get something going. We needed to get some energy, some momentum. We needed to show our fight, our resiliency, something that's won us a lot of games. When you're getting beat like that, you've got to show your character.

"I think that's where the path starts with all of us staying in the game and fighting to the end and trying to get some momentum or something going just to take from this game."

The Green Bay Packers' first look at life without Aaron Rodgers was not a pleasant one, as their offence sputtered with backup quarterback Jordan Love at the helm and the Kansas City Chiefs held on for a 13-7 victory. 

The Packers (7-2) had averaged 27 points during the seven-game winning streak that ended on Sunday after reigning MVP Rodgers missed the game following a positive coronavirus test during the week. 

The visitors did not get on the scoreboard until Love hit Allen Lazard for a 20-yard touchdown pass with five minutes remaining for his first career NFL TD.

That gave Green Bay some hope after their previous drive had ended with L'Jarius Sneed picking off a Love pass on Kansas City's five-yard line, but the Packers ran out of time. 

While the Chiefs (5-4) were not about to complain about the victory that got them back over .500, their season-long concerns about their offence continued as Patrick Mahomes had another unimpressive game. 

Former league MVP Mahomes completed 20 of 37 passes for just 166 yards but avoided throwing an interception for the first time since the season opener. His 54.1 completion percentage was his worst in a regular-season game since completing 51.2 per cent in a loss to the Las Vegas Raiders in Week 5 last season. 

 

Cardinals cruise past 49ers without Murray

The other red-hot team playing without their star quarterback fared better, as the Arizona Cardinals rolled to a 31-17 defeat of the San Francisco 49ers despite Kyler Murray's absence through an ankle injury. 

Veteran Colt McCoy stepped in for the Cardinals and completed 22 of 26 passes for 249 yards, while James Conner rushed for 93 yards and a pair of scores as Arizona improved to 8-1. 

Three turnovers proved critical for San Francisco (3-5) as the 49ers lost two fumbles in the first half and had trouble sustaining drives throughout the game, with only 23:13 of possession compared to 36:47 for Arizona. 

Jimmy Garoppolo completed 28 of 40 passes for 326 yards with two touchdowns and an interception for San Francisco. 

In Philadelphia, Dustin Hopkins' 29-yard field goal with two seconds to play gave the Los Angeles Chargers (5-3) a 27-24 victory over the Eagles (3-6). 

Cleveland Browns quarterback Baker Mayfield said he wishes "good friend" Odell Beckham Jr. well after the NFL franchise won for the first time since the split.

The Browns released star wide receiver Beckham Jr. on Friday, having been excused from practice on Wednesday and Thursday.

That came after both his father, Odell Beckham Sr., and four-time NBA MVP LeBron James complained on social media about Beckham Jr.'s lack of involvement in the Browns' offense.

Beckham Sr. posted a lengthy video on Instagram showing a number of occasions on which Mayfield failed to find his team-mate.

On Sunday, without three-time Pro Bowler Beckham Jr., the Browns routed the Cincinnati Bengals 41-16.

"I wish him well, I really do. My feelings haven't changed," Mayfield said of Beckham Jr.

"From a personal standpoint, he's a good friend of mine. ... But I'm worried about the guys in our locker room.

"I'm proud of these guys, how they were able to focus up despite all the bulls*** that was going on this week and how they were able to do their job. We're going to see if we can build on it and continue to get better."

Beckham Jr. is set to go on waivers on Monday and Mayfield added: "We still haven't talked. But that doesn't change things. I wish him well. I wish him the best in his career."

Mayfield completed 14 of his 21 passes for 218 yards and two touchdowns without an interception as the Browns improved to 5-4.

"We needed that win. Our whole locker room needed it. And they knew that. Played for each other," Mayfield said. "I trust the guys in this locker room.

"When adversity hit, nobody flinched. It was a long week. I'd be lying if I said otherwise. But proud of these guys."

Baker Mayfield threw a 60-yard touchdown to Donovan Peoples-Jones as the Cleveland Browns won without Odell Beckham Jr in Week 9, although Joe Burrow contributed to the Cincinnati Bengals' 41-16 defeat.

The Browns made the short trip to Cincinnati with Peoples-Jones back from a groin injury and in the lineup after fellow receiver Beckham was released at the end of a week that began with his father criticising quarterback Mayfield.

Beckham had underwhelmed this year since his return to fitness and his absence certainly was not felt on Sunday as Cleveland moved to 5-4 in a big AFC North matchup.

Before Mayfield came to the fore, though, Burrow endured a miserable start. Moments after a penalty reprieve when he was sacked on third and goal, the Bengals QB threw straight to Browns cornerback Denzel Ward on the goal line, covering Ja'Marr Chase and racing away for a 99-yard defensive TD.

Joe Mixon replied with the first of his two rushing scores, but Nick Chubb battled through contact to finish Cleveland's first drive with a TD, which Peoples-Jones added to as he caught Mayfield's first target to a wideout.

Long scores were the name of the day for the Browns, as Chubb's second saw him go 70 yards to score in the third quarter.

Burrow, who had scored three TDs in each of his previous three games, tying a Bengals record, was then picked off again throwing to Chase – this time by John Johnson III. Chase had earlier fumbled for a turnover of his own on a miserable day for two of Cincinnati's offensive stars.

Mayfield finished with 218 yards, two touchdowns and no interceptions on 14-of-21 passing. His second TD pass to David Njoku was set up by another throw to Peoples-Jones, who had 86 yards on just two catches.

Big upsets for Boys and Bills

The Dallas Cowboys had not lost since Week 1 but have a miserable record against the Denver Broncos, who had won the teams' past six meetings – their best ever run against a single opponent and the Cowboys' worst such streak. And six became seven as the Broncos won 30-16 in Dallas, holding their hosts scoreless until the fourth quarter despite Dak Prescott's return.

The Buffalo Bills also suffered a shock defeat as they went down 9-6 to the Jacksonville Jaguars in a game of zero touchdowns. Jaguars defensive end Josh Allen picked, sacked and recovered a fumble from his namesake, Bills QB Josh Allen.

However, the Baltimore Ravens survived a scare, as Lamar Jackson led them back from 17-3 down to make overtime, where Justin Tucker clinched a 34-31 win. Jackson is now 12-0 as a starter against NFC opponents.

Darnold spooked again

Sam Darnold said he was "seeing ghosts" when he threw four interceptions for the New York Jets against the New England Patriots in 2019, and Bill Belichick's defense has continued to spook the quarterback. He had three picks with the Carolina Panthers on Sunday and now has nine in just four career starts against New England, all four of which the Pats have won.

New England are hot on the heels of the Bills now, while AFC East rivals the Miami Dolphins snapped their seven-game losing run against the Houston Texans despite Tua Tagovailoa sitting out with a finger issue.

The Carolina Panthers activated star running back Christian McCaffrey from injured reserve, the NFL franchise announced on Saturday.

McCaffrey has missed five games, sidelined since Week 3 due to a hamstring injury.

The 2019 first-team All-Pro, who was designated to return earlier this week, is eligible for Sunday's showdown with the New England Patriots.

However, McCaffrey is no guarantee to play as the Panthers prepare to evaluate the 25-year-old on the day of the game.

McCaffrey has 201 yards and a touchdown in three appearances for the Panthers (4-4) this season.

Panthers quarterback Sam Darnold was also cleared from concussion protocol, though he continues to deal with a shoulder injury.

The Panthers are 4-2 in six regular-season games against the Patriots (including wins in the last two games, in 2013 and 2017), but New England beat Carolina 32-29 in Super Bowl XXXVIII (February 2004) – the only postseason game between these teams.

Carolina had 47 rushing attempts (for 203 yards) in their win against the Atlanta Falcons last week. It was the fourth-highest single-game total in Panthers history and their highest since 2009, per Stats Perform.

Darnold has lost each of his three career starts against the Patriots (one in each of the past three seasons), all with the New York Jets. The aggregate score for those three games is 99-17. He threw six interceptions with one touchdown pass in those games.

It is the one question that has dominated the 2021 NFL season: what is wrong with the Kansas City Chiefs?

The Chiefs, expected to return to juggernaut status after completely remodelling their offensive line in the wake of their blowout Super Bowl loss, have lurched from one unconvincing performance to another this campaign.

They sit at 4-4 heading into a matchup with the 7-1 Green Bay Packers that has lost a significant amount of its prestige due to Aaron Rodgers being ruled out after testing positive for coronavirus.

A 20-17 victory over the New York Giants on Monday did nothing to calm concerns about Kansas City and this weekend's visit of Green Bay may provide the answer as to how broken this Chiefs team really is.

Heading into a clash that could play a critical role in determining the direction of the 2021 Chiefs, Stats Perform assesses whether a contender that has often looked more like a pretender is as broken as many believe.

Explosives in short supply

The offense was expected to be at its devastating best in 2021 following the reconstruction of the offensive line.

That has not come to pass. The Chiefs have moved the ball efficiently for the most part of the season, they are ninth in yards per play with 5.99, but have seen turnovers continually undermine their production, which has tailed off to 4.84 yards per play over the last two weeks.

Patrick Mahomes has thrown a league-leading 10 interceptions, though a deeper dive into his performances this year strongly indicates he should not have thrown anything close to that number.

Indeed, Mahomes has delivered an accurate, well-thrown ball on 80.5 per cent of his passes this season, down from 81.1 in 2019 but significantly up from 76.7 in 2020, while his pickable pass percentage of 1.99 is the seventh-best among quarterbacks with at least 50 attempts.

Mahomes has thrown six turnover-worthy balls in 2021 with those numbers reflective of a series of accurate passes that have clanked off the hands of his receivers and into the arms of grateful defenders.

Does that mean the receiving corps is to blame for the Chiefs' struggles?

Not necessarily.

Star wideout Tyreek Hill has been credited with five drops and has played a part in some of those Mahomes' interceptions but the speedster is still consistently creating separation.

Hill has produced a burn, which is where a receiver wins his matchup with a defender on a play where he is targeted, on 71.9 per cent of his targets. That is well above average among receivers (minimum five targets) of 61.1. With his 3.0 burn yards per route superior to the league-wide average of 2.3 for his position, Hill is still a huge problem for opposing defenders along with tight end Travis Kelce.

The metrics suggest Kelce's play has tailed off a little. His burn percentage has dropped from 72.3 in 2020 to 67.6 this year and he is putting up 2.6 burn yards per route compared to 3.1 last year. He is still on the right side of the ledger in each of those categories, however.

Where there has been a clear drop-off from Kansas City's chief offensive weapons, is in explosive plays.

Hill delivered a big play on 35.6 per cent of his targets last season but is doing so 23.8 per cent of the time this year, comfortably below the league average of 29.1 for receivers. Kelce's dip is less dramatic, going from a big play rate of 36 per cent in 2020 to 28.9 in 2021.

That is compounded by the lack of depth the Chiefs have at receiver. Their investment in Mecole Hardman as a second-round pick in 2019 continues to look ill-advised. He is averaging a disappointing 1.7 burn yards per route while Demarcus Robinson (0.8) has also struggled when it comes to creating clear separation.

Byron Pringle is third among receivers with at least 10 targets with a big-play rate of 49.8 but with a relatively small sample size of 22 targets. He has a strong case for a greater role in a Chiefs offense that is turning the ball over and getting a declining rate of explosive plays from its top weapons.

And yet it is still not their biggest problem.

Dismal defense

The Chiefs not living up to their extremely high standards would not be receiving the same level of scrutiny if Kansas City did not also possess the worst defense in the NFL.

That defense is allowing a league-high 6.43 yards per play, they are third-worst in the NFL against the pass (7.79) in that regard and fifth-worst (4.64) versus the run.

Kansas City's defense is one with problems in essentially every area. Their front has found it difficult to generate pressure, ranking 29th in pass rush win rate according to Stats Perform data.

Their issues in that regard forced their hand in trading for Melvin Ingram, who through seven games with the Steelers had a win rate of 30 per cent, above the average of 21.88 for edge rushers.

Yet there are also glaring concerns in the secondary.

Of the four Chiefs' cornerbacks to have been targeted at least 10 times, only Rashad Fenton (1.71) has a burn yards allowed per snap rate that is the right side of the league average of 1.97.

Perhaps an even bigger problem is the play of much-maligned safety Daniel Sorensen, who has given up a big play on 37.8 per cent of his targets, the third-highest rate among players at his position.

As such, Sorensen can expect to be attacked consistently by the Packers' offense, which should still have plenty of confidence of moving the ball despite Rodgers' absence.

All you need is Love?

The Packers have not been efficient, ranking a disappointing 20th in yards per play, but may have found a winning formula on the ground, having rushed for at least 100 yards in five of their last six games. 

Given the Chiefs' deficiencies in stopping the run, Kansas City can expect to see heavy doses of Aaron Jones and A.J. Dillon.

Yet at some point, the Packers must put their faith in Rodgers' backup Jordan Love in his first start, providing Steve Spagnuolo's defense with cause for optimism.

In his final season at Utah State in 2019, Love delivered a well-thrown ball just 66.74 per cent of the time, putting him significantly shy of the average of 73.20 per cent for Power 5 and Group of 5 quarterbacks with at least 100 attempts. His pickable pass rate of 8.21 per cent was the third worst.

And he deteriorated under pressure, his well-throw rate dropping to 54.89 and his pickable pass percentage increasing to 12.03 when under duress.

With limited NFL experience to his name, the Chiefs will hope the accuracy issues and his troubles against pressure continue at the NFL level.

But the impact of any inability to deal with the pass rush from Love will not be felt if the Chiefs cannot drastically improve their success in defeating opposing pass protectors.

The Chiefs are clearly a long way short of their usual standards but, with Mahomes more accurate than in recent years and their top receivers still getting separation from defenders, to label them broken may be a stretch.

However, if they cannot get the job done in a high-profile matchup that has, at least on paper, drastically tilted in their favour due to the controversy surrounding Rodgers, then it will be a fitting adjective for a team long since associated with much more complimentary language.

After a turbulent week in Green Bay, Jordan Love said Friday he is healthy and ready to make his first NFL start Sunday against the Kansas City Chiefs. 

Love became the last quarterback standing for the Packers after starter Aaron Rodgers and third-stringer Kurt Benkert tested positive for coronavirus earlier this week. Green Bay have since signed veteran Blake Bortles as insurance. 

A first-round pick in the 2020 NFL Draft, Love made his NFL debut in the team's season-opening loss to the New Orleans Saints after watching from the sidelines all of last season. 

The Packers have won seven in a row since that defeat and it will be up to Love to maintain that momentum against Patrick Mahomes and the defending AFC champions at Arrowhead Stadium. 

"I've been preparing myself for that moment and now's the time," Love told reporters Friday. 

"Obviously there's going to be some nerves there. There always is, walking out of the tunnel. The atmosphere is going to be rocking. But I have a lot of confidence in myself, a lot of confidence in this team, and those dudes are going to take care of me.

"We've had a great week of practice. Those dudes are attacking it, and they're giving me a lot of confidence to go out there and play my best, too."

Though he has no consequential game experience as a pro, Love – who turned 23 on Tuesday – got first-team reps throughout the offseason as Rodgers was absent amid a dispute over his future with the team. 

Head coach Matt LaFleur said he is looking forward to seeing what his presumptive quarterback of the future can do against the Chiefs. 

"I think he's come a long way, but by no means is he a finished product," LaFleur said. "It's going to be a great opportunity for him to get his feet wet for the first time in a meaningful game, being that it's the regular season.

"So it'll be a great learning experience for him, and I'm just excited for his opportunity."

Kyler Murray and DeAndre Hopkins are both game-time decisions for the Arizona Cardinals, head coach Kliff Kingsbury has confirmed.

Arizona travel to play NFC West rivals the San Francisco 49ers on Sunday, looking to bounce back from suffering their first loss of the year against the Green Bay Packers.

Murray threw multiple picks and no touchdowns in a game for the first time in his career as Arizona lost 24-21 to the Packers, ending the only perfect record left in the NFL.

The Cardinals (7-1) could be without their starting quarterback and leading wide receiver on the road against the Niners.

Murray (ankle) and Hopkins (hamstring) both missed the open section of practice on Friday, having also not been involved on Wednesday or Thursday.

"He is progressing but we will see how he feels Sunday and go from there," Kingsbury said about Murray.

"I know he wants to play. He knows how important a divisional game is [but] we are not going to put him out there if he can't function.

"I don't know if [Hopkins] will go full speed or not."

Arizona (7-1) got a 17-10 win at home over San Francisco (3-4) this season, but that was the only game in which they have not scored at least 21 points this year. 

Murray has had a spectacular year so far, putting himself in the MVP conversation.

The third-year QB ranks second for completion percentage (72.7) and has 17 touchdown passes to seven interceptions, as well as a further three scores on the ground.

Murray's 24 passing plays of 25-plus yards are tied for the most in the NFL with Tom Brady, and he leads an efficient offense which has led him to the fourth-highest passer rating (110.4) in 2021.

Veteran backup Colt McCoy will play if Murray is unable to take the field.

Hopkins leads the team in catches (35) and receiving yards (486), but at 60.8 yards per game is operating well below his production from last season (87.9) amid his injury struggles.

The Cardinals also put wide receiver A.J. Green on the reserve/COVID-19 list this week.

The 49ers, meanwhile, beat the Bears 33-22 in Chicago last week, snapping a four-game losing streak and scoring their most points since a 41-33 win over the Detroit Lions in Week 1. 

In an unusual sequence of results since the start of last season, the Niners are 1-10 at home and 8-4 on the road. 

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