The New York Giants have ruled out Saquon Barkley for Thursday's game against the San Francisco 49ers due to a sprained right ankle the star running back sustained Sunday against the Arizona Cardinals.

ESPN reported Monday that Barkley was expected to miss around three weeks after injuring his ankle in the latter stages of New York's 31-28 Week 2 win, though Giants coach Brian Daboll told reporters Tuesday the 2022 Pro Bowl selection was feeling better and the team had yet to make a determination on Barkley's status.

With Barkley unavailable, the Giants will have former 49er Matt Breida and Gary Brightwell as their top two running backs for Thursday's matchup.

Breida has spent the majority of his seven-year career as a backup, but did rush for 814 yards in 14 games with San Francisco in 2018. Brightwell's most extensive action came in the 2022 regular-season finale, in which he rushed for 60 yards on 11 carries against the Philadelphia Eagles. 

Neither has the credentials of Barkley, who finished fourth in the NFL with a career-high 1,312 rushing yards and scored 10 touchdowns in 2022 to help the Giants to their first playoff appearance in six years. The 26-year-old accounted for 27.7 per cent of New York's total yards from scrimmage last season, the sixth-highest rate of any player for his respective team.

Barkley also played a major role in Sunday's win, in which the Giants overcame a 21-point third-quarter deficit. The 2018 No. 2 overall pick had both a rushing and receiving touchdown in the second half and ended the game with 63 rushing yards on 17 carries along with six receptions for 29 yards.

The two-time Pro Bowler has been slowed by ankle problems in the past, however. Barkley missed three games in 2019 with a high ankle sprain and four in 2021 with an injury to his left ankle.

The Giants will also be without starting left tackle Andrew Thomas for a second straight game due to a hamstring injury he suffered in the team's season-opening 40-0 loss to the Dallas Cowboys. 

New York Giants running back Saquon Barkley said sitting out the 2023 season is among his options after he failed to reach a long-term deal with the team. 

The star running back and the Giants failed to reach a new contract on Monday, meaning Barkley will earn $10.1 million this season on a fully guaranteed one-year deal without the long-term security of a multi-year pact.

In an interview on a podcast that was recorded before Monday’s deadline, Barkley discussed the negotiations for players on a franchise tag to reach a new multi-year deal with terms. He used an expletive several times in noting a holdout would thumb his nose at the Giants and his teammates and show them his true value.

“Anybody who knows me knows that’s not something I want to do,” Barkley said. “But is it something that crossed my mind, I never thought I would ever do that. But now I’m at a point where it’s like, ‘Jesus, I might have to take it to this level. Am I prepared and willing to take it to the level. I don’t know. That’s something I gotta sit down. I gotta sit down and talk to my family. I gotta sit down and talk to my team, gotta really strategise about this. Can’t just go off emotions.”

Barkley totalled a career-high 1,312 rushing yards last season, the fourth-most in the NFL and the most by a Giants player since Tiki Barber’s 1,662 yards in 2006.

The two-time Pro Bowler has rushed for 4,249 yards and 29 touchdowns in 60 games with the Giants since he was the second overall pick out of Penn State in 2018.

Running back Saquon Barkley reiterated his desire to stay with the New York Giants after their Divisional Round defeat to the Philadelphia Eagles.

The Giants were well beaten by the Eagles, who progressed with a 38-7 victory at Lincoln Financial Field on Saturday.

Barkley recorded 10 touchdowns in the regular season, but made just nine carries for 61 yards against Philadelphia.

After a strong season for him and the Giants though, the 25-year-old said he wants to stay with the franchise "for life" despite his contract expiring this year.

"I don't want to jump to any conclusions. I've been vocal about how I feel and where I want to be," he said. "That's outside my control. I wanted to show the Giants, show them that the guy that they drafted is still here. I hope I did that.

"Everyone knows I would love to be a Giant for life, but I really can't give a 100 per cent answer. It's out of my control. Sometime this week, I'll get a conversation with my agent Kim [Miale] and see what's up.

"The way we played for each other this year, it was special. Obviously, it didn't end the way we would have wanted it to end. Not just because of the record or because we made it to the playoffs, this is probably one of my favourite teams of all time."

Quarterback Daniel Jones – who was sacked five times in Philadelphia – also sees his deal run out at the end of the season, and was less certain about his future intentions than Barkley.

"We will cross that bridge when we get there. I really enjoyed playing here," Jones said. "I appreciate all of those guys in the locker room. It is a special group of guys and I have really enjoyed being a part of it.

"We will figure out where that goes, but I have nothing but love and respect for this organisation and the group of guys in the locker room."

Coach Brian Daboll showed respect to the Eagles for their performance, admitting his team just second-best in every area of the contest.

"Give Philly credit. They did everything better than we did [Saturday]," Daboll said. "Tough game. We really got beat in all facets, so it wasn't one thing in particular. It was a team game, and we just didn't get it done. Congratulations to Philly. They get to move on, and unfortunately we don't."

The New York Giants snapped a 10-season streak without a playoff win by defeating the Minnesota Vikings 31-24 in Sunday's Wild Card game.

New York had not won a playoff game since capping the 2011 season with the franchise's fourth Super Bowl, but they rode a pair of strong performances from their offensive centrepieces to upset the 13-4 Vikings on the road.

Quarterback Daniel Jones became the first player to ever tally 300 passing yards, two passing touchdowns and 70 rushing yards in a playoff game, while star running back Saquon Barkley had 109 yards from scrimmage and scored two rushing touchdowns.

Incredibly, neither team committed a turnover, with Vikings quarterback Kirk Cousins also delivering an impressive 273 yards and two touchdowns, but he was unable to produce in the fourth quarter.

It was the Vikings who scored first through a Cousins quarterback sneak from the opening drive of the game, but their lead did not even last until quarter time as Barkley and receiver Isaiah Hodges found the endzone in response.

After trading scores in the second and third periods, the Vikings pulled things level at 24-24 early in the fourth with a field goal, but Jones answered with a defining 12-play, 75-yard drive, setting up Barkley for the game-winning touchdown.

The Vikings had two drives and seven minutes to try and tie things up, but the Giants' defense rose to the occasion and closed it out.

New York will try to continue their march to the Super Bowl next week in the Divisional round against the league-leading Philadelphia Eagles (14-3).

The NFL season has reached the point where the playoff picture truly starts to take shape.

Many players have proven themselves in an unpredictable 2022 campaign while others have fallen below expectations.

Stats Perform has focused on the former, selecting a pick for every position in Week 11, including the defense/special teams slot, for players that deserve to be in your consideration.

If you have any of these rostered, or they are somehow available on the waiver wire, now is the time to make your move!

Quarterback – Josh Allen, Buffalo Bills vs Cleveland Browns

Questionable for the entire week leading up to Week 10 against the Minnesota Vikings, Allen was not at his best as he threw two interceptions and had a critical late fumble in the fourth quarter, but still racked up the points.

A tally of 29 completions was Allen's highest since Week 2 against the Tennessee Titans (42), with a total of 330 yards his third-highest of the season. Cause for concern, however, is the fact Allen has thrown more interceptions (six) than touchdowns (three) over the past three weeks.

The Browns' defense has struggled to defend the pass, though, conceding 11.91 yards per completion on average, the sixth-worst in the NFL. Look for Allen to bounce back here.

Running back – Saquon Barkley, New York Giants vs Detroit Lions

No player has more rushing yards in the NFL this season than Barkley (931), who had 152 against the Houston Texans in Week 10, his highest return since 164 yards in Week 1 against the Titans.

With rushing touchdowns in seven of his nine games this season, including four in his last five, Barkley is almost guaranteed to yield a strong return of fantasy points – especially against a vulnerable Lions defense.

Only the Texans (1,636) have allowed more rushing yards this season than the Lions (1,448), while an average of 5.34 yards allowed per carry is third worst in the league – both numbers that will encourage Barkley to run riot.

Wide receiver – CeeDee Lamb, Dallas Cowboys @ Minnesota Vikings

The Cowboys' trip to Minnesota is a matchup where elite receivers will be the focus, with Justin Jefferson of the Vikings and the Cowboys' CeeDee Lamb top of the agenda – the latter being our pick for the week.

In the Week 10 loss to the Green Bay Packers, Lamb caught 11 of 15 targets and racked up 150 yards, reaching three figures for the first time this season, with two receiving plays of 25 or more yards.

Opponents against the Vikings have racked up a total of 2,537 yards, giving the Minnesota defense the sixth-worst record in that regard. The Vikings are also allowing 32 plays of at least 20 yards – with only five teams in the NFL conceding more.

Tight end – George Kittle, San Francisco 49ers @ Arizona Cardinals

Utilised predominantly as a blocker in Week 10, George Kittle should see more of the ball against a Cardinals defense that has allowed a total of 2,619 passing yards this season, behind only the Atlanta Falcons and the Titans, and 17 passing touchdowns, the fourth-most across the NFL.

When targeted, Kittle is a reliable option to get the ball moving downfield, catching 29 of 41 targets and securing a first down on over half of them (15). A total of 340 yards this season has seen 165 yards after catch, illustrating his power when he gets moving.

Kittle boasts a burn rate, which is when a receiver wins his matchup against a defender on a play where he is targeted, of 65.9 per cent – ranking seventh among tight ends who have been targeted at least 30 times.

Defense/Special teams – Philadelphia Eagles @ Indianapolis Colts

Defeat to the Washington Commanders in Week 10 brought an end to the Eagles' eight-game winning streak but the 4-5 Colts should be an easier proposition for the NFC favourites to deal with.

The Eagles defense has allowed just 1,813 passing yards overall, the second-best record behind the Denver Broncos (1,769). Philadelphia's 13 interceptions is the joint-best tally in the NFL along with the Bills – intercepting 4.1 per cent of passing attempts they have faced.

Only three teams have recorded more sacks than the Eagles (29) this season, with opponents losing a total of 214 yards in the process – only the Tampa Bay Buccaneers (217) and Cowboys (225) have seen opponents lose more yards on sacks.

Patrick Mahomes and Saquon Barkley were recognised as the respective AFC and NFC Offensive Player of the Week after flying starts to the new NFL season.

Mahomes led the Kansas City Chiefs to a dominant 44-21 Week 1 win at the Arizona Cardinals.

The 2018 MVP leads the league in passing touchdowns (five), passing yards (360) and quarterback rating (144.2) at this early stage.

Only Joe Burrow matched Mahomes' 22 passes for first downs, while he did not throw an interception and was not sacked, making him an obvious choice as the standout player in the AFC.

Minkah Fitzpatrick, who played a vital role in the Pittsburgh Steelers' wild win over Burrow's Cincinnati Bengals, is the AFC Defensive Player of the Year.

The Steelers safety caught a pick-six from Burrow's first pass of the game and later, crucially, blocked Evan McPherson's PAT to take the game to overtime.

Cade York was more accurate as time expired in the Cleveland Browns' dramatic victory over the Carolina Panthers, kicking the winning field goal to earn AFC Special Teams Player of the Week recognition.

In the NFC, New York Giants running back Barkley was the standout player on offense, stealing the show against a Tennessee Titans team featuring two-time rushing yards and rushing TDs leader Derrick Henry.

Barkley has the most rushing yards at this early stage with 164 and a score. His 68-yard run in the drive that culminated in his TD was the longest carry of the week.

The fifth-year superstar, who has been hampered by injuries since an outstanding rookie season, also caught a Daniel Jones pass for the decisive two-point conversion in a 21-20 Giants victory.

Also honoured in the NFC were debutant Seattle Seahawks linebacker Uchenna Nwosu and Philadelphia Eagles cornerback Zech McPhearson.

Nwosu sacked the Denver Broncos' former Seattle quarterback Russell Wilson and forced a fumble from Melvin Gordon at the one-yard line, while McPhearson fielded the Detroit Lions' attempted onside kick to set up a Boston Scott touchdown in an Eagles win.

New York Giants general manager Joe Schoen says his team are not shopping Saquon Barkley, even though he had taken calls from other NFL teams about the running back.

Barkley was drafted to huge fanfare at number two overall in 2018 and was named Offensive Rookie of the Year as he racked up 15 total touchdowns in his debut campaign.

The 25-year-old has struggled to recapture those performances since, with injuries hindering him along the way as a torn ACL in 2020 limited him to just two games that year.

As the Giants rebuild with a new GM and head coach, there was trade talk at the scouting combine about Barkley, who is now playing under his fifth-year option worth $7.2million.

But Schoen has clarified that his previous comments about listening to calls did not mean he was keen to see the player move on.

"I reached out to him immediately after all that happened at the combine," Schoen told ESPN about Barkley, who averaged just 3.7 yards per carry in 162 attempts last year.

"Again, it would be irresponsible for the team if a team calls – I think 31 other GMs would say the same thing – if somebody is going to call and offer you something ridiculous, you're going to listen. 

"It doesn't mean you're going to make a deal or say yes to it. That was taken a little bit out of context. So I haven't called one team on Saquon Barkley.

"Everybody ran with that from the combine. I said I would listen if people called on any players. It would be irresponsible if I didn't. That doesn't mean I'm going to do every deal. 

"I've got calls about a few of our players. He's one where a couple teams have reached out. 

"But I'm not shopping Saquon Barkley. The guy was the number two pick in the draft for a reason. He's got a lot of talent and I'm looking forward to working with him."

New York have not won a playoff game since their Super Bowl triumph at the end of the 2011 season.

Brian Daboll, who like Schoen has just arrived from the Buffalo Bills, is the team's fifth head coach since two-time Super Bowl winner Tom Coughlin departed after the 2015 campaign.

Giants co-owner John Mara was also asked about Barkley this week and called him "a great representative" for the team who "could have a very big year".

But he stressed any football decisions lay with Schoen and Daboll.