Flamengo and Boca Juniors reached the Copa Libertadores semi-finals as Internacional and LDU Quito bowed out on Wednesday.

Gabriel 'Gabigol' Barbosa scored to earn Flamengo a 1-1 draw away to Brazilian rivals Internacional and a 3-1 victory on aggregate.

Flamengo – led by Jorge Jesus and boasting former Atletico Madrid star Filipe Luis – carried a 2-0 lead into the return leg in Porto Alegre.

Internacional gave themselves hope just past the hour-mark when Rodrigo Lindoso glanced a header beyond Flamengo goalkeeper Diego Alves.

Gabigol – tipped to make his loan deal from Serie A giants Inter permanent – extinguished Internacional's chances with five minutes remaining after side-footing into an empty net, having received a simple pass from first-leg hero Bruno Henrique.

Flamengo, who claimed their one and only Libertadores title in 1981, will meet Gremio in the final four as they return to the semis for the first time in 35 years.

Meanwhile, Boca reached the semi-finals for the second successive year following their 0-0 draw at home to Antonio Valencia's LDU Quito midweek.

There were no goals scored in Buenos Aires but Boca still progressed 3-0 on aggregate after their comprehensive victory last week.

Daniele De Rossi came off the bench with 10 minutes remaining as six-time champions and last season's runners-up Boca await holders River Plate or Cerro Porteno in the semis.

Boca Juniors took a giant step towards the Copa Libertadores semi-finals, while Flamengo beat Internacional on Wednesday.

Runners-up last year, Boca comfortably beat a 10-man LDU Quito 3-0 in the first leg of their quarter-final in Ecuador.

Boca, with Daniele De Rossi watching from the bench, opened the scoring in the 11th minute, Ramon Abila getting on the end of an Alexis Mac Allister pass to make it 1-0.

LDU Quito were dealt a huge blow just before half-time as Jefferson Orejuela was sent off for a rash challenge.

Emanuel Reynoso doubled Boca's lead with a brilliant 25-yard free-kick, and Kevin Minda was sent off while on the bench for the hosts.

Boca sealed a fine win with nine minutes remaining, Luis Caicedo's poor defending eventually leading to the defender scoring an own goal.

If Boca and rivals River Plate, who play Cerro Porteno on Thursday, advance, they will meet in the semi-finals in a rematch of last year's controversial decider.

In the day's other game, Bruno Henrique's late brace saw Flamengo beat Internacional 2-0 at the Maracana.

Henrique tapped in a Gerson pass for the 75th-minute opener before producing a fine finish soon after to seal Flamengo's first-leg victory.

Boca Juniors booked their spot in the Copa Libertadores quarter-finals, while Flamengo completed a comeback against Emelec to progress on Wednesday.

Runners-up last year, Boca recorded a 2-0 victory over Athletico Paranaense at La Bombonera to secure a 3-0 aggregate win.

Ramon Abila scored the opening goal of the second leg with a powerful finish in the 57th minute.

The hosts sealed their win deep into additional time through Eduardo Salvio as they moved into the last eight, where they will face Ecuadorian outfit LDU Quito.

Flamengo needed penalties to overcome Emelec, winning 2-0 in Rio de Janeiro before a 4-2 shoot-out success.

Gabriel Barbosa, on loan from Inter, struck twice in the opening 19 minutes – including from the penalty spot – to bring the tie level at 2-2 on aggregate.

Diego Alves, who developed a reputation for saving penalties during his time with Valencia, saved from Dixon Arroyo in the shoot-out before Nicolas Queiroz hit the crossbar, sending Flamengo through.

Next up for Flamengo are Internacional, who claimed a 2-0 win at home to Nacional to wrap up a 3-0 aggregate success.

Cerro Porteno set up a quarter-final meeting with defending champions River Plate thanks to a come-from-behind 2-1 win over San Lorenzo in Asuncion, after their first leg finished 0-0.

Carlos Tevez helped Boca Juniors to an away win in the first leg of their Copa Libertadores last-16 tie against Athletico Paranaense, while Internacional also left it late.

Last year's runners-up, Boca edged to a 1-0 victory in Curitiba as Tevez had an impact off the bench on Wednesday.

The former Manchester City and Manchester United forward played a one-two with Alexis Mac Allister, the Brighton and Hove Albion loanee curling a wonderful effort into the top corner from 25 yards in the 83rd minute.

The hosts had a chance to equalise after being awarded a penalty following a VAR review, but former River Plate forward Marco Ruben's 95th-minute spot-kick bounced back off the post.

The result left Boca in a good position ahead of next week's return leg at La Bombonera.

Internacional also claimed an away win, edging Nacional 1-0 in Montevideo thanks to Paolo Guerrero's 90th-minute goal.

The Peru great produced a clinical finish from inside the area to see the Brazilian outfit edge to victory.

Elsewhere, a 10-man Emelec claimed a 2-0 win at home to Flamengo and Cerro Porteno drew 0-0 at San Lorenzo.

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