Bayer Leverkusen continued their march towards the Bundesliga title as they edged to victory at Freiburg to restore their 10-point lead at the top.

Xabi Alonso’s side remain unbeaten in the league this season and ran out 3-2 winners on Sunday afternoon.

Leverkusen remain on course to end Bayern Munich’s run of 11 successive titles after efforts from Adam Hlozek and Patrik Schick saw them build a two-goal lead after Ritsu Doan had pulled the hosts level following Florian Wirtz’s early opener.

Yannik Keitel pulled another back for Freiburg but Leverkusen saw out the closing stages to win their 22nd league game of the campaign.

Borussia Dortmund came from behind to beat Eintracht Frankfurt 3-1 after their former player Mario Gotze had given the visitors the lead.

Karim Adeyemi equalised before half-time and Mats Hummels gave Dortmund the lead late on, with a stoppage-time Emre Can penalty securing the points.

Runaway Serie A leaders Inter Milan were held to a 1-1 draw by reigning champions Napoli.

Inter have lost just once in the league this season and appeared on course for another win as Matteo Darmian struck just before half-time.

Napoli’s title defence has been non-existent but they rallied for a point at San Siro as Juan Jesus levelled with nine minutes left on the clock.

The draw means Inter’s lead at the summit sits at 14 points, with nearest rivals AC Milan cutting the deficit following a 3-1 victory at Verona.

Theo Hernandez, Christian Pulisic and Samuel Chukwueze were on target for the visitors, who never looked troubled despite Tijjani Noslin temporarily halving the lead.

Third-placed Juventus had to settle for a 0-0 draw at home to Genoa as Dusan Vlahovic was sent off late on as he was booked twice for remonstrating with the referee.

Lorenzo Pellegrini scored the only goal of the game as Roma beat Sassuolo 1-0 while Fiorentina’s trip to Atalanta was postponed after Joe Barone, a Fiorentina director, was rushed to hospital.

Barcelona eased to a 3-0 win at Atletico Madrid to move within eight points of Real Madrid at the top of LaLiga.

On a comfortable night for Xavi’s side, they saw off their fellow Champions League quarter-finalists as Joao Felix gave the visitors a half-time lead.

Robert Lewandowski and Fermin Lopez goals completed a fine night for the Catalan giants, while Atleti had Nahuel Molina sent off in stoppage time.

At the other end of the table, rock bottom Almeria celebrated their first league win of the season as Leo Baptistao scored the only goal in a 1-0 victory at Las Palmas.

Celta Vigo, meanwhile, pulled five points clear of the relegation zone with a 2-1 comeback win at surprise strugglers Sevilla.

Youssef En-Nesyri had put the home side in front but two goals in six minutes from Carles Perez and Jorgen Larsen secured the points for Celta.

Jorge Cuenca struck as Villarreal beat Valencia 1-0 while Real Betis lost 2-0 at Rayo Vallecano courtesy of goals from Florian Lejeune and Sergio Camello.

Kylian Mbappe hit a hat-trick as Ligue 1 leaders Paris St Germain thrashed Montpellier 6-2 at the Stade de la Mosson.

Vitinha opened the scoring for the visitors before Mbappe bagged his first of the evening, only for the home side to draw level before the break through Arnaud Nordin and a Teji Savanier penalty.

PSG would make sure of the points in emphatic style as Mbappe added two more either side of a Lee Kang-in effort, with a late Nuno Mendes goal completing the rout.

The three nearest challengers to PSG all dropped points as Martin Satriano’s goal for second-placed Brest earned them a 1-1 draw at home to Lille, who sit fourth.

A thrilling game at Stade Louis II saw third-placed Monaco concede a last-gasp equaliser in a 2-2 draw with Lorient – with both sides finishing with 10 men.

A first-minute Wilfried Singo own goal put Lorient in front before Formose Mendy put through his own goal to level and Youssef Fofana’s effort just before the hour put the home side ahead.

Denis Zakaria then saw red for Monaco with Lorient reduced to 10 in the 89th minute as Tosin Aiyegun was dismissed, only for Tiemoue Bakayoko to secured a point for Lorient in stoppage time.

Rennes beat Marseille 2-0 as Martin Terrier and Benjamin Bourigeaud scored for the hosts, while Reims were 2-1 winners over Metz and Clermont beat Le Havre by the same scoreline.

David Moyes took the handbrake off West Ham and watched them race into the last eight of the Europa League with a 5-0 win over Freiburg.

Hammers boss Moyes uncharacteristically named an attacking line-up in a bid to repair the damage of the 1-0 first-leg defeat in Germany last week.

He was rewarded with a sparkling display as goals from Lucas Paqueta, Jarrod Bowen, Aaron Cresswell and two from Mohammed Kudus – including a sensational solo effort – secured a 5-1 aggregate win and a place in a European quarter-final for a third-successive season.

As a consequence the Hammers may have also done some of their Premier League rivals a favour, with the result pushing England ahead of Germany in UEFA’s coefficient rankings, which could mean an extra spot in Europe next season.

Despite some indifferent domestic form, West Ham – last season’s Europa Conference League winners – seem to come alive on these European nights.

Two years ago, at the same stage of the same competition, they memorably overturned a 1-0 first-leg deficit against Spanish Europa League specialists Sevilla.

There were fears that that crackling atmosphere might be difficult to recreate, with many fans unable to make the match due to the unusual 5.45pm kick-off time.

But the London Stadium was still almost full and it erupted after just nine minutes as Freiburg saw their advantage wiped out.

Cresswell swung in a third-successive corner, Tomas Soucek stooped to flick the ball on and the unmarked Paqueta slid it in at the far post.

Just after the half-hour mark, West Ham had their second as Bowen celebrated his latest call-up to the England squad in style, shrugging off the attentions of Freiburg captain Christian Gunter before lashing home from 20 yards.

Freiburg still posed a threat, though, with Roland Sallai firing across goal and wide just to let West Ham know the tie was still very much in the balance at half-time.

That lasted until six minutes into the second half, when Bowen’s square ball across the box was deflected out to Cresswell, lurking on the edge of the area.

The left-back, who was the fall guy in Frankfurt two years when his red card in the semi-final against Eintracht cost West Ham dearly, took a touch before leathering the ball inside the far post.

The best was still to come, despite there being little sign of danger when Kudus picked the ball up deep inside his own half.

The former Ajax wideman sprinted around 70 yards, slicing through the heart of the Freiburg defence before casually rolling the ball into the net.

No wonder Kudus felt the need to borrow a photographer’s stool and sit down in front of the delirious home fans as his team-mates celebrated around him.

The rest had clearly done Kudus good, as he promptly collected Bowen’s lay-off and dispatched a low drive from 20 yards to complete West Ham’s five-star display.

West Ham drew a blank in the Black Forest as they slipped to a 1-0 defeat in the first leg of their Europa League last-16 meeting with Freiburg.

Jarrod Bowen and Lucas Paqueta missed golden opportunities to give the Hammers a lead to take back to the London Stadium next week.

But instead they will have to come from behind after they were hit by a late sucker punch from Freiburg substitute Michael Gregoritsch.

They were also denied what looked a clear penalty for handball in stoppage time after the referee refused to change his decision despite checking the pitchside monitor.

Nine months to the day since they lifted the Europa Conference League trophy in Prague, West Ham were back on their continental travels, and against familiar opponents.

Freiburg were the visitors to east London for the final group game just 84 days ago when a 2-0 win secured top spot for the Hammers.

West Ham also won 2-1 on their previous visit to south-west Germany in October, and travelled buoyed by back-to-back Premier League wins following a below-par start to the year.

Boss David Moyes, keen on another strong run in Europe, named his strongest line-up with cup goalkeeper Lukasz Fabianski replacing Alphonse Areola in the only change from Saturday’s victory at Everton.

West Ham were, as usual, happy to let their opponents have the ball but Freiburg gave them a scare when Roland Sallai’s through-ball split their defence.

Fortunately, Lucas Holer hit his shot into the ground and straight at Fabianski.

Moments later Bowen made a horrible mess of West Ham’s only chance of the first half.

The forward, who has not scored in Europe since his famous last-minute winner against Fiorentina in the Czech capital, peeled away at the far post to meet a Mohammed Kudus cross but badly fluffed his volley.

At the start of the second half Ghana winger Kudus cut inside Freiburg full-back only to curl his shot straight at keeper Noah Atubolu.

Bowen then scampered down the right wing and crossed for Paqueta, who also scuffed a volley wide.

A James Ward-Prowse corner should have been converted by Konstantinos Mavropanos but the centre-half’s header grazed the far post.

Paqueta then met another superb cross from Kudus but the finish, a simple header, again did not match the quality of the delivery, before Atubolu did well to tip Bowen’s curler wide.

Tomas Soucek also fired straight at Atubolu and Bowen just missed Aaron Cresswell’s cross before Freiburg struck.

A sloppy pass from Edson Alvarez gifted them possession and when Sallai took aim from the edge of the area, his wayward shot was tapped in by Gregoritsch.

Four minutes into stoppage time the ball struck the arm of Freiburg youngster Noah Weisshaupt in the area but after a long VAR check, referee Alejandro Hernandez checked the replay and stuck to his guns.

West Ham are still being affected by the sickness bug that contributed to their 5-0 rout by Fulham on Sunday.

David Moyes has revealed that some players are struggling with illness as the Hammers look to finish top of Group A of the Europa League by securing at least a draw against SC Freiburg on Thursday night.

The London Stadium clash is the first of four matches in three competitions over 10 days for West Ham, who have already qualified for the knockout phase but are hoping to progress as top seeds and thereby avoid the burden of a play-off over two legs.

“We’ve had a few people with a bit of illness. We’ve still got a few lingering with it in the last day or two, but we think we’re OK,” Moyes said.

“I don’t think it’s anything that will keep people out for weeks or anything like that, there has just been a bit of sickness and all sorts going on. It’s just been keeping us under the weather a little bit.”

West Ham leaked five goals at Craven Cottage, ending a six-match unbeaten run which had lifted them to ninth in the Premier League as well as offering sight of direct entry into the Europa League’s round of 16.

“I obviously didn’t enjoy the weekend’s game. Whatever happened before that doesn’t make it any easier,” said Moyes, who gave his players two days off at the start of the week in anticipation of the hectic period coming up.

“We’ve had a really gruelling schedule and the trips we’ve had caught up with us a little bit.

“Hopefully we can correct that and get back to our normal way which is winning and playing better than we did do.

“We had a little bit of illness that didn’t help with the chopping and changing. Hopefully we can get back to normality.”

West Ham are the current Europa Conference League champions after toppling Fiorentina 2-1 in the final in June and Moyes sees the competition as an important stage for his team.

“The last few years we’ve had some really good nights at London Stadium. I think back to Seville and Alkmaar,” he said.

“Some of the games have been special, special nights for us. But we’re not quite at that stage yet, it’s still the group.

“We’ve won the group for the last two years and winning it three years in a row would be really tough because Freiburg are a good team.

“We’re in Europe after Christmas and that’s the most important thing, whether we’re first or second. We’ll try to be first, but that’s the big thing for us.

“The Premier League will always be first and foremost for me, but the cup competitions are something that we take as seriously as we can.”

Bayern Munich boss Thomas Tuchel is expecting the unexpected when his side returns to Bundesliga action on Sunday against Freiburg.

Bayern sit third in the table, unbeaten in their opening six matches, but had to fight back from 2-0 down to salvage a point in last week’s 2-2 draw at Leipzig.

Tuchel’s side also came from behind in midweek to win 2-1 in Copenhagen and make it two wins from two Champions League group matches.

After quickly refocusing on this weekend’s domestic challenge, Tuchel told a press conference: “We really want to get all three points, but we know how difficult it will be, so we’ll have to show up on Sunday.

“Freiburg change their system a lot and I’m 100 per cent sure that they’ll do everything possible to make our lives difficult. We’ll have to be ready for that.”

Freiburg have not beaten Bayern in the Bundesliga in 14 attempts – their last win being in 2015 – but they knocked Tuchel’s side out of the DFB Cup last season.

Lucas Holer scored a 95th-minute penalty as Freiburg came from behind to win the quarter-final tie 2-1 in Tuchel’s second game in charge of Bayern.

The Bavarians’ last three matches have all been on the road and Tuchel admitted after Tuesday night’s win in Denmark that the travel had taken its toll.

“It was a long journey, which the boys are feeling the effects of,” he said. “We’ve played a lot of away games recently.”

Tuchel confirmed Matthijs de Ligt has still not recovered from the knee injury sustained in last month’s 7-0 home win against Bochum, but Raphael Guerreiro was back in training.

The Portugal midfielder has been sidelined since injuring his calf during pre-season.

“Unfortunately, Matthijs de Ligt has not made as quick a recovery as we had hoped for. Dayot Upamecano and Kim (Min-jae) are fit to play,” Tuchel added.

Freiburg, whose cup success at the Allianz Arena last season was their only win against Bayern in Munich, will be without suspended midfielder Nicolas Hofler.

Michael Gregoritsch and Yannik Keitel both missed Freiburg’s 2-1 home Europa League defeat to West Ham on Thursday and remain doubtful.

David Moyes saluted his “maverick” forward Lucas Paqueta after the 2-1 Europa League win at Freiburg, even though he drives him mad.

Freiburg’s nickname is the Breisgau Brazilians due to their flamboyant style of play, but it was West Ham’s Samba star Paqueta who stole the show.

He put them ahead after only nine minutes with a towering header from a cross by Jarrod Bowen, celebrating his return to the England squad.

Paqueta then spent the rest of the evening tormenting the hosts with his array of flicks, tricks and occasional theatrics.

“It was a bit of an old-fashioned goal, down the side with a good cross, and then a great header like an old-fashioned centre forward. I really enjoyed watching it,” said Hammers boss Moyes.

“Jarrod played well but Lucas was terrific. He drives me mad sometimes but everybody who watched him would have said this player has got incredible talent.

“There is a word that goes around, a maverick. He is that for us.

“It is really important we get him in and adapt to him and accept some of his things he may not do, things which I would say are conventional.

“But we are really enjoying him at the moment and he is terrific at taking the ball under pressure – but also there are moments when I say: ‘what are you doing’?”

The match may have taken place on the edge of the Black Forest, but it was never going to be a piece of cake for the Hammers against a side eighth in the Bundesliga.

They were also up against 34,000 noisy fans, with no away supporters allowed to attend following incidents during West Ham’s Europa Conference League final triumph in June.

Freiburg equalised after half-time through Roland Sallai, but Nayef Aguerd’s header from a James Ward-Prowse corner made it two wins from two in Group A and a 17th match undefeated in Europe, a record for an English club.

“It’s a brilliant achievement, I’ve said to the boys we need to keep it going. Winning the game tonight was most important,” added Moyes.

“I’m really pleased. We played very well especially, in the opening 20 or 30 minutes.

“They came back, which I expected. They got better and we had moments when we played very well but we mainly won the first half. We had to then be good defensively.”

Union Berlin secured Champions League qualification for the first time in their history as Schalke suffered relegation from Bundesliga on the final day of the season.

Rani Khedira's 81st-minute winner at home to Werder Bremen saw Union pip Freiburg to fourth place in the German top flight, with Urs Fischer's side booking their spot in UEFA's top club competition for next season.

There was no such good fortune for Schalke, though, as they dropped back down to 2. Bundesliga following a 4-2 defeat to third-placed RB Leipzig on Saturday.

As Bayern Munich celebrated edging out Borussia Dortmund for the title on goal difference, Stuttgart will be left to fight for their top-flight status in a play-off after a 1-1 draw at home to Hoffenheim.

Stuttgart will face either Hamburg or Heidenheim, with whoever finishes third in the German second division due to battle with Sebastian Hoeness' men for a place in Bundesliga next term.

Had Stuttgart won, Augsburg would have been in that play-off after a 2-0 final-day defeat at Borussia Monchengladbach, while Bochum pulled clear of danger with a 3-0 victory over Bayer Leverkusen.

Massimiliano Allegri has warned his Juventus side about the strength of Sporting CP ahead of the two teams clashing in the Europa League quarter-final. 

Juventus host the Primeira Liga side in the first leg on Thursday night, after the Bianconeri eliminated Freiburg in the last 16, while Sporting beat Arsenal. 

Allegri's side sit seventh in Serie A after a 15-point deduction for alleged transfer irregularities, while Sporting are fourth in Portugal's top-flight and are unbeaten in their last 11 games in all competitions.

"Tomorrow is a difficult match," Allegri said at a press conference on Wednesday. "It is an important quarter-final against a team that has been on a positive run for 11 games now.

"Sporting's coach [Ruben Amorim] is young and very good. He brought the league title back to the club [in 2020-21] after 19 years.

"We have to do things the right way tomorrow to have an advantage for when we go to Lisbon."

Juventus will be boosted by the return of key players on Thursday, including Paul Pogba, whose injury-hit season has seen him play just 35 minutes since re-signing from Manchester United last summer.

"Pogba is on his feet, which we are happy about," added Allegri. "Now we are working on improving his condition.

"Tomorrow he will be available and will be on the bench. Alex Sandro and [Dusan] Vlahovic are both available, but [Mattia] De Sciglio is not."

Juventus are second-favourites to win the Europa League behind United, but Allegri is not look beyond the quarter-final.

"Clearly it would be fantastic to get to play the final," he said. "But before then, there are still four games to face, starting with home and away against Sporting.

"So, it's too early to talk about playing in a final. We're only thinking about this next game, and we'll continue step by step."

Joshua Kimmich apologised for his "unsportsmanlike" behaviour after celebrating Bayern Munich's win over Freiburg in front of the home fans.

Bayern edged Saturday's tight Bundesliga contest 1-0 at Europa-Park Stadion thanks to Matthijs de Ligt's long-range strike early in the second half.

The victory came four days on from Bayern's elimination from the DFB-Pokal to the same side, which Freiburg took delight in reminding their opponents before the match.

Kimmich clenched both fists and gestured towards home supporters after Bayern exacted some revenge on Saturday, causing a mass confrontation on the pitch.

Freiburg midfielder Nicolas Hofler accused Kimmich of "unsportsmanlike and unnecessary" conduct and added his opposite number "should not feel the need to provoke fans".

When Hofler's comments were put to Kimmich after the match, the Germany international accepted he perhaps went too far with his celebrations.

"There were many emotions involved," he told reporters. "It was an important win for us – the DFB-Pokal defeat hurt deeply. 

"I got carried away; I shouldn't be doing that. You can say it was unsportsmanlike."

Asked what provoked his actions, Kimmich added: "During the warm-up, there was a 10-minute film about the Pokal game being shown [on the big screen]. 

"I can understand anyone who describes [my reaction] as unsportsmanlike. In the end it's just emotions."

 

Thomas Tuchel's side wasted some big chances either side of De Ligt's strike, but were also reliant on goalkeeper Yann Sommer producing a couple of important saves.

Freiburg were previously unbeaten in a club record 12 home games, but Bayern did enough to come away with a win that keeps them two points clear of Borussia Dortmund.

"We knew it would be a difficult game," head coach Tuchel said. "They were 12 games unbeaten at home and beat us in the Pokal midweek. 

"In the end, I think the win was deserved. We had big chances to score in both halves. I'm happy that we won and kept a clean sheet. It was so important."

De Ligt's long-ranger, which took a touch on its way past Mark Flekken, generated an expected goals (xG) value of just 0.02.

The centre-back took particular delight in scoring past his Netherlands international team-mate, who made seven saves either side of that winning goal.

"I always score against Mark in training, so I thought I'd just give it a try," De Ligt said. "Our performance was good, but we still have a lot of room for improvement."

Bayern have won two of their three games since Tuchel took charge and now turn focus to the first leg of their Champions League quarter-final with Manchester City.

"We have to be brave. We have to believe in ourselves, be smart, have tactical solutions and go to the limit of our physical efforts," Tuchel said of Tuesday's tie in Manchester. 

"City have been playing at an absolute top form for weeks. We need to regenerate and hope to have everyone fit."

Bayern Munich exacted some revenge on Freiburg and maintained their two-point lead on Borussia Dortmund at the Bundesliga summit with a 1-0 win at Europa-Park Stadion.

Thomas Tuchel's side were eliminated from the DFB-Pokal by Freiburg on Tuesday, but they dug deep four days on to remain on course for an 11th successive domestic title.

Matthijs de Ligt gave Bayern the key breakthrough six minutes into the second half with a thunderous long-range strike, either side of some fine goalkeeping from Mark Flekken.

Fourth-place Freiburg had been unbeaten in seven league games, but they were unable to respond as Bayern made it back-to-back league wins since Tuchel took charge.

Flekken was kept busy in the Freiburg goal in a lively – albeit goalless – first half to keep out efforts from Serge Gnabry, Sadio Mane, Benjamin Pavard and Leroy Sane.

Those missed chances almost came back to haunt Bayern when Ritsu Doan got an outstretched leg to Michael Gregoritsch's cross and sent the ball against the right-hand post. 

Bayern's breakthrough arrived through their first on-target attempt of the second half, with De Ligt's deflected shot from 25 yards swerving past a helpless Flekken.

Flekken produced one of the saves of the season soon after to deny Mane from close range, while Sane clipped the ball over the crossbar with just the goalkeeper to beat.

Sane squandered another chance when through one-on-one, but only after Yann Sommer had produced a superb save at the other end to keep out Roland Sallai's shot.

Gnabry struck the post in the closing seconds, while Matthias Ginter glanced wide from the final meaningful attack, but Bayern successfully saw out another crucial victory.

Bayern Munich head coach Thomas Tuchel urged his players to retain a positive mindset ahead of a crucial run of fixtures in the Bundesliga and Champions League.

Following a shock 2-1 defeat at home to Freiburg in the DFB-Pokal on Tuesday, Bayern travel to face the same opponents in the league on Saturday before going up against Manchester City in the first leg of their Champions League quarter-final next Tuesday.

Speaking at a press conference on Friday, Tuchel repeatedly mentioned a need to be "positive" despite the cup setback.

"We need to continue with a positive approach, we can be angry but still be positive," he said, later adding: "We need a reaction, but we would have needed one even if we won.

"People don't want to hear it but there were positive things in [the Freiburg] game... Things can happen where the result is probably not right after a game like this but we have to accept it.

"We are lacking a bit of precision in the last pass, a bit of trust, cohesion, creativity. We need form and that will only come back if we remain positive, even though we were unhappy with the result."

On the reaction of his players following the loss to a 95th-minute Lucas Holer penalty at the Allianz Arena, Tuchel added: "They are very critical of themselves. I was telling them the same thing I have told you, that we just have to accept it, that the coach is talking about positive things about the game even though no-one wants to talk about it.

"We can have a bad mood for a couple of days but that doesn't help anyone, you need a positive mindset to move forward."

Tuchel confirmed the Freiburg game will come too early for injured pair Eric Maxim Choupo-Moting and Mathys Tel, while Dayot Upamecano misses out through suspension.

When asked who can play as the striker in Choupo-Moting's absence, he said: "Mathys Tel can play as a nine, that was his answer when I asked him his position, but he is injured.

"Sadio Mane and Serge Gnabry can play there as well, they will be my players of choice."

The former Borussia Dortmund and Chelsea boss was not keen to look beyond Saturday to Tuesday's trip to Manchester, but he acknowledged he cannot use Freiburg as preparation given the difference in approach.

"I don't believe that we can practice the things we need against Man City, Freiburg play a completely different way," he said.

Thomas Muller was left feeling bitter after Bayern Munich were saddled "with the shambles" of another DFB-Pokal failure against Freiburg.

The Bundesliga leaders slipped to a 2-1 defeat in the quarter-finals, after Lucas Holer's 95th-minute penalty condemned them to a late loss.

Dayot Upamecano had handed Bayern the lead in Thomas Tuchel's second game in charge, before Nicolas Hofler squared matters in the first half.

It means the club will miss out on the DFB-Pokal final for the third straight season, and Muller concurred the loss represented a blow to their pride.

"[There is] a certain bitterness," he told Sky Sport Germany. "We're eliminated. You can't make amends anymore. You're standing there with the shambles.

"It's over again. Of course that scratches your sense of honour. Freiburg hardly had a chance to score, but if you lose in the end, you have to face the questions."

The result means it is one win and one loss for Tuchel since he succeeded Julian Nagelsmann, having picked up a 4-2 win over Borussia Dortmund in his first game.

Muller appreciated the need to adapt to their new coach, but still stressed the blow of their exit would linger, particularly with a rematch in the Bundesliga on Saturday.

"We [have] now had two games with a new coaching line-up," he added. "Now, we're emotionally down to earth. We have to manage that as a group.

"We will get back together on Thursday, we will try to improve. But now, there is disillusionment and brutal disappointment."

Thomas Tuchel accepted responsibility for Bayern Munich's DFB-Pokal quarter-final exit, after they suffered a late 2-1 loss against Freiburg.

The Bundesliga leaders looked set for extra-time at Allianz Arena, after Dayot Upamecano's header was cancelled out by Nicolas Hofler.

But Jamal Muisala's penalty concession deep into second-half stoppage time allowed Lucas Holer to seal a last-gasp victory for the visitors from the spot.

In only his second game in charge since replacing Julian Nagelsmann, Tuchel acknowledged he had to shoulder the blame for their defeat.

"I am not really angry," he said. "We conceded two goals with two shots. I can’t remember another chance from Freiburg.

"The last pass, [and the] precision obviously, are all an issue. But still, we had good moments we could have used, but [we] just could not keep it up.

"In the end, it is our fault. We are very disappointed [to lose] a quarter-final at home. Of course, I am responsible."

Tuchel made a winning start to his Bayern career with a decisive 4-2 win over old club Borussia Dortmund, where he previously won the DFB-Pokal.

His failure to back it up with progress to the semi-finals of Germany's major knockout competition will take the shine off his early impression.

Bayern can claim immediate revenge on Saturday when they travel to Freiburg for a reverse fixture in the Bundesliga, looking to consolidate top spot.

They also remain in the mix for Champions League honours, and return to European competition against Manchester City next Tuesday.

Lucas Holer's last-gasp penalty saw Freiburg snatch a dramatic 2-1 victory against Bayern Munich in the DFB-Pokal quarter-finals to end Thomas Tuchel's hopes of a domestic double.

The tie appeared to be headed to extra time, until Jamal Musiala handled Nicolas Hofler's strike, enabling Holer to secure a shock win.

Bayern had looked the likelier of the two teams to claim a late winner, after seeing Dayot Upamecano's first-half header cancelled out by Hofler's excellent volley.

It means Tuchel, in his second game since replacing Julian Nagelsmann, will miss out of the chance of both Bundesliga and Pokal glory as Christian Streich's side proceed to the last four.

Massimiliano Allegri was critical of Juventus' second-half performance after they reached the Europa League quarter-finals with a 2-0 win at Freiburg on Thursday.

Juve built on their 1-0 first-leg advantage as Dusan Vlahovic converted a first-half penalty after home defender Manuel Gulde was controversially sent off for handball inside his own area.

Federico Chiesa added a late second after entering the fray as a substitute, as Juventus maintained their bid for a first major continental title since they won the Champions League in 1996. 

However, Allegri was displeased with Juventus' performance after Freiburg went down to 10 men, saying the Bianconeri must improve if they are to progress further in the competition.  

"The team got a good result as we progressed. We made a lot of mistakes in the second half with our ball handling, and we need to improve," he said at his post-match press conference.

"We can't play a second half like this against a team of 10. We were made to defend our own box. The second half should have been better. We need to work; we made a lot of wrong decisions.

"Against 10 we lowered our attention and pace. The result is good – excellent even – but let's not get excited because we're in the quarter-finals. We have to think about what we did in the second half and improve."

Chiesa's stoppage-time goal – a driven strike which found the net via the foot of the post – was just his second since returning from an anterior cruciate ligament injury in November, and the Italy international is looking to find consistency in the coming weeks.

"My first thought is to be available to the coach. Unfortunately I haven't been there in the last few games," he said. "There's still a bit of discomfort, but I'm working even harder to be more ready.

"Unfortunately my father [former Italy striker Enrico Chiesa] had similar injuries. It's a path of great obstacles to come back, but even after that, the journey continues. I just have to stay calm."

Meanwhile, the decision to send Gulde off after his outstretched arm was struck by Federico Gatti's shot infuriated Freiburg boss Christian Streich, as did a failure to punish Wojciech Szczesny for seemingly picking up a Manuel Locatelli back-pass.

"We were brave, we went for it," the Freiburg boss said. "Then there was the situation with the red card and the penalty. That was of course a difficult situation for us.

"I'm speechless. In both games, after every foul, a Juve player plays the ball away. Always. It's a complete mystery to me. 

"Then there's the intentional back-pass that isn't blown. It's difficult to accept. Something that was crucial was let go."

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