Paris Saint-Germain ceded the Ligue 1 title despite winning their final match of the season 2-0 at Brest.
Neymar missed a first-half penalty at Stade Francis-Le Ble before a Romain Faivre own goal and Kylian Mbappe's 27th league goal of the season made it a routine win for Mauricio Pochettino's men.
But Lille's 2-1 victory over Angers meant Christophe Galtier's side completed an incredible triumph by a solitary point.
Results elsewhere were kinder to Brest, with Nantes' 2-1 loss to Montpellier sparing them participation in the relegation play-off.
PSG's title hopes took an early blow when Jonathan David gave Lille the lead at Angers and Neymar then spurned a 19th-minute penalty after Faivre's rash foul on Angel Di Maria.
Brest goalkeeper Gautier Larsonneur engaged in some kidology by standing near his right-hand post for the kick and Neymar duly rolled his shot past the other upright.
Di Maria took matters into his own hands before half-time, albeit with a huge slice of fortune, when his right-wing corner deflected off Faivre and looped beyond Larsonneur.
Brest might have gone in level, only for Steve Mounie to power a close-range header over from Brendan Chardonnet's cross.
News of Lille's comfortable position perhaps informed the lack of intensity at the start of the second half, with PSG creating little of note from open play and Di Maria rippled the side-netting with a free-kick.
Mounie erred again when he burst clear of a haphazard visiting backline in the 65th minute, shooting at Keylor Navas' legs.
PSG were indebted to Navas once more soon afterwards, the former Real Madrid man's positioning impeccable when Gaetan Charbonnier met Mounie's knockdown.
Mbappe had existed on the fringes of the contest but was alert to round Larsonneur in the 71st minute and kept his composure to finish after being bundled to the floor by Jean-Kevin Duverne in front of the unguarded net.
Larsonneur denied substitute Mauro Icardi and Mbappe as Brest appeared increasingly forlorn – their fate ultimately saved by others.
Skriniar hails PSG team-mates Mbappe and Dembele as best in the world
Kylian Mbappe and Ousmane Dembele were hailed as two of the best players in the world right now by Paris Saint-Germain team-mate Milan Skriniar after their starring roles in a 4-1 triumph over Lorient.
The duo were each on target twice at the Stade du Moustoir in Wednesday's contest as Luis Enrique's men took another step closer to the Ligue 1 title.
Speaking to RMC Sport, centre-back Skriniar had high praise for PSG's superstar duo after a game where he felt the team were not at their best.
"I don't think it was our best performance, because at 2-0, we could have controlled the match better," he said.
"We lost too many easy balls but we know that up front we are very strong. I think we have the two best players in the world [Mbappe and Dembele] at the moment so we are happy for the victory.
"For me, they are the two best players in the world. We know their qualities, they help always the team with their goals, with their actions, with everything they do.
"It's easy to play with them."
PSG are not quite over the line in Ligue 1 yet as second-placed Monaco defeated Lille 1-0 later on Wednesday.
It means PSG are 11 points clear of their rivals with only four games remaining and the title will be theirs with victory over Le Havre at the Parc des Princes on Saturday.
Coventry City 2-3 Hull City: Tigers win five-goal thriller to keep play-off hopes alive
Hull City kept their hopes of gatecrashing the Championship play-offs alive with a thrilling 3-2 win over beaten FA Cup semi-finalists Coventry City on Wednesday.
Noah Ohio scored the winner with his first touch after coming on as a second-half substitute as Hull moved within three points of sixth-placed Norwich City with two games to play.
Coventry, meanwhile, saw their own hopes of returning to Wembley Stadium for a second successive play-off final all but ended, as they sit six points further back with three matches remaining.
Three days on from their remarkable comeback against Manchester United, the Sky Blues twice fought back to level things at Coventry Building Society Arena. Jaden Philogene's shot squirmed under goalkeeper Bradley Collins to put Hull ahead 31 minutes in, but Kasey Palmer levelled within five minutes with a stunning free-kick.
Hull went back ahead in controversial circumstances on the stroke of half-time, Liverpool loanee Fabio Carvalho converting from the penalty spot despite replays showing Joel Latibeaudiere's foul on Liam Delap took place outside the area.
Mark Robins' men again dragged themselves back into the game as Bobby Thomas headed Jay Dasilva's cross in just before the hour mark, but it was Liam Rosenior's visitors who found a winner.
Thomas went from hero to villain as his poor back pass sold Collins short, and Ohio got a toe to the ball to score the winner, keeping Hull's hopes of Premier League football intact.
Van Dijk: Liverpool have 'no chance' in title race after derby defeat
Virgil van Dijk conceded Liverpool might be out of the Premier League title race after they suffered a surprise 2-0 defeat to Everton in Wednesday's Merseyside derby.
Jarrad Branthwaite and Dominic Calvert-Lewin scored in either half to give the Toffees their first win over Liverpool at Goodison Park since 2010.
Liverpool struggled to find a way through the Toffees' defence despite dominating for long periods, and the Reds' captain says they will not outlast Arsenal and Manchester City without major improvements.
Speaking to Sky Sports, Van Dijk said: "If we play like today, then we have no chance to consider ourselves in the title race.
"We have to just focus on the next game and that will be a tough one anyway, so we will see.
"We're very disappointed, in so many ways. I think everyone has to look at their own performances. Did they really give everything, and do they really want to win the league?
"We're still fighting and there are still games after tonight, but if we play like we did overall in the game today – not winning challenges and giving the referee a chance to give free-kicks like he did many times, then you have no chance to win the title."
SportsMax is the Caribbean sports channel of choice, committed to providing sporting content of the highest quality to the Caribbean, delivered by a team of highly innovative, passionate and qualified professionals.
(876) 619-7629
digitalmedia@sportsmax.tv
