Jurgen Klopp said losing star captain Jordan Henderson to injury was a "massive blow" after Liverpool's faltering Premier League title defence hit a new low on Saturday.
Henderson suffered a groin injury as champions Liverpool were upstaged by Everton 2-0 in Saturday's Merseyside derby at Anfield.
After Richarlison put Everton ahead in the second minute, Henderson was forced off the field by the half-hour mark as Liverpool's injury crisis mounts.
Gylfi Sigurdsson's penalty with seven minutes remaining condemned Liverpool to their first home defeat to neighbours Everton since 1999.
"It's a massive blow losing Hendo [Jordan Henderson] again, massive, but Nate [Nathan Phillips] played a super game," Liverpool manager Klopp told reporters post-match.
"Again, we got used to it, unfortunately, that we have to change things,
"We just try to set up again for the next game and as long as we have 11 players we will do that.
"The boys are still full of desire, I see that. But to change a football game, a result, to get the result you have to be decisive in the right moments, defensively and offensively and that's what we are lacking."
Liverpool were already without Fabinho – himself a stand-in for Joe Gomez, Joel Matip and Virgil van Dijk.
Van Dijk sustained a potentially season-ending knee injury in October's reverse fixture at Goodison Park.
Liverpool have lost four consecutive home league games for only the second time, last doing so back in December 1923 – when they were also defending top-flight champions.
Everton picked up their first win over Liverpool in 24 meetings in all competitions (D12 L11) – ending what was the Reds' longest ever unbeaten run against a single opponent.
Slot pursuit shows Liverpool running out of options, suggests Carragher
Liverpool's pursuit of Feyenoord boss Arne Slot proves there is "a dearth" of elite coaches currently on the market, according to former Reds defender Jamie Carragher.
On Wednesday, widespread reports claimed Liverpool have entered talks with Feyenoord, who will reportedly demand at least €10million (£8.5m) in compensation to part with Slot.
Slot joined Feyenoord in July 2021 after leaving AZ Alkmaar, leading the Eredivisie giants to the Europa Conference League final – which they lost to Roma – in his first campaign at the helm.
The club's second league title in 20 years followed in 2022-23, and though Feyenoord are set to relinquish their crown to PSV this term, they beat NEC Nijmegen to lift the KNVB Cup on Sunday.
Xabi Alonso was thought to be Liverpool's primary target to replace outgoing boss Jurgen Klopp, but the former midfielder – who was also interesting Bayern Munich – has announced his intention to stay with Bayer Leverkusen.
Sporting CP's Ruben Amorim was also linked with the post, but it is thought he is no longer a leading candidate.
Speaking in his role as a Sky Sports pundit ahead of Wednesday's Merseyside derby between Liverpool and Everton, Carragher warned the job will be a major step up for Slot if he is appointed.
"What I would say is I think going from Feyenoord to Liverpool is a huge jump, and I think it shows at this moment that there's probably a dearth of real top managers out there," he said.
"Initially it was Xabi Alonso, it's only his first full season as a manager. Then there was talk of Ruben Amorim from Sporting, again he's only 39. Now Arne Slot looks like he's the favourite.
"I don't think it's like Rafael Benitez coming in, or Jurgen Klopp. Benitez came in off the back of two LaLiga titles and a UEFA Cup, Klopp had won a couple of league titles with Borussia Dortmund.
"Liverpool were in a different space back then, certainly the team I was part of with Benitez… we were a team looking to qualify for the top four. It was the same when Klopp came in.
"Liverpool are in a different area now, fancying themselves to challenge for the Premier League every season, and in next season's Champions League they'd expect to reach the quarter-finals at least.
"I think it's a huge jump but he's obviously a great coach with a great track record with the clubs he's been at so far. We'll see."
Rangnick confirms Bayern Munich contact
Ralf Rangnick has confirmed Bayern Munich have been in contact over their soon-to-be vacant coaching position.
Bayern are on the lookout for a new coach, with Thomas Tuchel set to depart at the end of the season.
The Bundesliga giants wanted to appoint Xabi Alonso, but the 42-year-old snubbed their advances, and those of Liverpool, to stay at Bayer Leverkusen.
Bayern's search has now seemingly led them to Rangnick, the former Manchester United interim boss who is now coach of Austria's national team.
Rangnick, though, is paying full attention to Austria's upcoming Euro 2024 campaign.
"There has been contact from the side of Bayern Munich and I have informed the Austrian Football Association," Rangnick said in an interview with 90 Minuten.
"We have a very trusting relationship. My focus is on the Austrian national team. We are focusing completely on the European championships.
"I feel very well here. At the moment there is no reason to intensively deal with this."
Rangnick has plenty of Bundesliga experience, having previously coached Stuttgart, Schalke, Hoffenheim and RB Leipzig.
While Bayern's hopes of securing a 12th Bundesliga title have long since been over, they remain in with a shout of salvaging their season, with a Champions League semi-final against Real Madrid on the horizon.
According to Opta's predictive model, Bayern only have a 37 per cent chance of overcoming Los Blancos, however.
Austria, meanwhile, have been drawn into a Euro 2024 group that also includes Poland, the Netherlands and tournament favourites France.
Rangnick's team will face Les Bleus on June 17, before taking on Poland four days later, and rounding off their group campaign against the Dutch on June 25.
Haaland out of Brighton clash, confirms Man City boss Guardiola
Manchester City will be without Erling Haaland when they take on Brighton, Pep Guardiola has confirmed.
Haaland missed Saturday's FA Cup semi-final victory over Chelsea with a muscular injury he sustained against Real Madrid last week.
And the issue will also see the striker, who has scored 20 Premier League goals this season, miss out against the Seagulls on Thursday.
"Erling is not ready for tomorrow," said Guardiola, who added that City will be able to call on Phil Foden and John Stones.
"It's not a big issue but he's not available."
Haaland has scored, on average, every 109 minutes in the league this season.
However, the Norwegian has actually underperformed his expected goals (xG) of 23.7.
He has also chipped in with five assists, giving him an overall goal contributions tally of 25. Haaland has created 28 goalscoring chances for team-mates across the campaign.
After Arsenal's 5-0 thrashing of Chelsea on Tuesday, reigning Premier League champions Manchester City sit four points off the summit in third place, albeit with two games in hand.
Second-place Liverpool will aim to move level on points with the Gunners by beating Merseyside rivals Everton on Wednesday.
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