Henry Slade has been left out of England's squad for the Autumn Nations Series but Kyle Sinckler returns.
Slade missed the 2-1 series win in Australia after undergoing shoulder surgery, but has been back in action for Exeter Chiefs.
The centre was not among the 36 players Eddie Jones has called up for the Tests against Argentina, Japan, New Zealand and South Africa next month.
Sinckler is back in the fold after recovering from a back injury, while wing Cadan Murley has earned a first call-up.
Val Rapava Ruskin and Raffi Quirke have also been recalled less than a year before the Rugby World Cup starts in France.
Anthony Watson, George Ford and Jamie George are among the absentees due to injury.
Head coach Jones said: "There are a number of disappointed players who have been left out. Their job is to make sure they go back to their clubs and play so that they have to be selected. They all know what they have to do.
"This is a very strong, vibrant squad and a number of good players have been left out. We are pleased with the depth and strength of the squad."
England squad:
Forwards: Alex Coles, Luke Cowan-Dickie, Tom Curry, Ellis Genge, Joe Heyes, Jonny Hill, Maro Itoje, Courtney Lawes, Lewis Ludlam, George McGuigan, Val Rapava Ruskin, David Ribbans, Bevan Rodd, Sam Simmonds, Kyle Sinckler, Jack Singleton, Hugh Tizard, Billy Vunipola, Mako Vunipola, Jack Willis.
Backs: Henry Arundell, Joe Cokanasiga, Owen Farrell, Max Malins, George Furbank, Will Joseph, Jonny May, Cadan Murley, Guy Porter, Raffi Quirke, Marcus Smith, Freddie Steward, Manu Tuilagi Jack van Poortlviet, Ben Youngs.