India have announced Prithvi Shaw will miss the entire Test series against Australia with an ankle injury - but Hardik Pandya is fit to join up with his team-mates for the final two games.

Opening batsman Shaw suffered an ankle injury while fielding during a warm-up fixture prior to the series, ruling him out of the opener in Adelaide - which India won - and the ongoing second Test in Perth.

The teenager - who made 134 on debut against West Indies in October - has now been ruled out for the remainder of the tour, with uncapped batsman Mayank Agarwal called up as a replacement.

However there was better news for India concerning Pandya, who has been called up to the squad after overcoming a back injury picked up during the Asia Cup, the all-rounder proving his fitness in domestic cricket.

Both Agarwal and Pandya will be available for selection for the third Test in Melbourne, by which time the series could well be level at 1-1.

Set 287 for victory in Perth, the tourists never recovered from losing two wickets inside the opening four overs of their run chase, eventually reaching the close on 112-5.

Nathan Lyon and Josh Hazlewood both claimed two wickets apiece for the hosts, and the latter is confident they can go on and complete the job.

"There's a bit of work to be done - we've just got to stay disciplined and patient, hit the right areas and five wickets is what we need," paceman Hazlewood told the media.

"It's been a bit of a long time between wins, but any time I'm playing in Australia, with the Australian cricket team, we feel pretty confident. 

"Especially the bowlers feel very confident in getting 20 wickets and getting a result. As we saw last year [in the Ashes win over England], we got home four times out of five. 

"So we're feeling pretty confident of putting that into practice more often than not this summer."

Nathan Lyon claimed the key wicket of Virat Kohli to turn the second Test in Australia's favour, with India finishing the fourth day on 112-5 after being set 287 in Perth.

The home side suffered a batting collapse in their second innings, slipping from 192-4 to 243 all out as Mohammed Shami claimed Test-best figures of 6-56, yet still look favourites to clinch a series-levelling victory.

India stuttered early in their pursuit of an attainable target, slipping to 13-2 before tea. Mitchell Starc tempted KL Rahul to chop on to depart for a duck, while Cheteshwar Pujara fended a rising delivery from Josh Hazlewood through to wicketkeeper Tim Paine.

However, it was Lyon who struck perhaps the most telling blow in what has been a see-saw contest, getting Kohli caught at slip by Usman Khawaja, who had earlier made 72 with the bat, for 17.

The off-spinner also dismissed Murali Vijay - the opener bowled through the gate on 20 - before Ajinkya Rahane (30) fell to Hazlewood prior to the close, slicing an ambitious drive to Travis Head at point.

Hanuma Vihari battled through to reach stumps unbeaten on 24 alongside Rishabh Pant (9 not out), but India still require a further 175.

Australia will be confident of picking up the five wickets they require during Tuesday's play, though they made their task tougher than it needed to be by losing a clatter of wickets after lunch.

When Khawaja had Paine for company out in the middle, the hosts appeared on course to set their opponents a sizeable fourth-innings target. Instead, they folded quickly once the fifth-wicket alliance ended with Paine (37) undone by a vicious short ball from Shami.

The home captain had again exchanged words with opposite number Kohli during his time in the middle, with umpire Chris Gaffaney heard on the stump microphone telling both players to keep their cool in the heat of battle.

Aaron Finch's return to the crease - the opening batsman had retired hurt when on 25 the previous day - did not last long as he gloved Shami's next ball through to wicketkeeper Pant, with the same bowler-fielder combination also accounting for Khawaja six runs later.

Shami dismissed Lyon too to get his first six-wicket haul in the format, but Australia's last-wicket pairing of Starc and Hazlewood added 36 valuable runs, the former last out for 14 to leave the latter unbeaten on 17.

Tensions continued to run high during the second Test between Australia and India as Tim Paine and Virat Kohli were involved in another confrontation.

Paine and Kohli, the captains of their respective teams, exchanged words at stumps on Sunday.

The pair's battle continued on day four in Perth, where they came together during Australia's second innings.

Umpire Chris Gaffaney tried to keep the duo cool, picked up by the stump microphone telling Paine and Kohli to stop.

"That's enough. Play the game, you guys are the captains," he was heard saying in audio broadcast by Channel 7.

Paine, seemingly initially ignoring Gaffaney's request, said: "Keep your cool, Virat."

Australia pushed their lead to 233 at lunch as they remained on track to level the series.

Paine (37) and Usman Khawaja (67) were unbeaten at the break as the hosts reached 190-4.

Mitchell Starc will continue to ignore criticism from Shane Warne, saying he "may as well retire" if he listens to the former Australia star.

Warne has again been unflattering in his assessment of Starc's bowling in recent weeks, writing in a newspaper column after the first Test against India that some of his play had been "atrocious".

Those comments appeared to reignite a feud from 2015, when Warne criticised Starc's body language and the Australia man riposted that he had "nothing to prove" to the bowling great.

Reports suggested Starc was unhappy with this analysis, but he says he is not putting much stock in Warne's opinions, insisting the focus will remain on beating India.

"I still don't know what he said," Starc told FOX after day three of the second Test on Sunday. "I've been told about it.

"But if I keep listening to Warney, I may as well retire. I'll just keep going about my stuff, as I have done over the week."

Australia led by 43 runs after the first innings in Perth, stretching that advantage to 175 as they reached stumps at 132-4 on Sunday.

Starc (2-79) took the early wickets of Murali Vijay and Cheteshwar Pujara as India batted for the first time, before their recovery was halted by the controversial dismissal of captain Virat Kohli.

Jasprit Bumrah said India were "a little surprised" with Virat Kohli's contentious dismissal on day three but is confident they can chase down any target to beat Australia at Perth Stadium.

Australia opener Aaron Finch was cleared of serious damage after taking another blow to the finger on day three of the second Test against India at Perth Stadium.

Usman Khawaja is unconcerned about his disappointing start to Australia's Test series against India.

After a stunning 141 to salvage a draw against Pakistan in Dubai was followed by knee surgery in October, Khawaja has scored just 41 runs across three innings versus India.

The batsman, who has only found the boundary once from 205 balls faced during the series, has been relied upon to shoulder a greater share of responsibility at the top of the order with David Warner and Steve Smith suspended.

Despite a difficult start against the top-ranked Test side, Khawaja is remaining upbeat about his chances of making an impact.

"Cricket is a funny game, it goes in circles," Khawaja told a post-match news conference.

"I've scored a lot of runs this year. A lot of runs in first-class cricket over in Glamorgan, then [for] 'Aussie A', and then in the UAE. 

"There's going to be a couple of innings here and there where I don't, and that's just part of the game. Nothing changes a lot. Credit to the bowlers when they bowl well to you. 

"If you're not scoring runs you don't have to reinvent the wheel. You just go out there next time and get some more runs.

"It could be a lot worse. I could get three first-ballers."

Australia were all out for 326 in the first session on Saturday and had India in trouble at 8-2 in reply, but unbeaten fifties from Virat Kohli and Ajinkya Rahane got the tourists to stumps in a strong position at 172-3.

Khawaja hopes his team can make an early breakthrough on day three and put some pressure on what appears to be a long India tail.

"If we get a couple of wickets early [on Sunday] and break this partnership right now - it's not an easy wicket to start off on," said Khawaja.

"If we do that we'll have our chance at that tail, but we still have to be quite disciplined."

The presence of Virat Kohli at the crease has Ishant Sharma confident that India can seize control of the second Test against Australia on day three.

India captain Kohli ended the second day unbeaten on 82, leading the tourists to a solid position on 172-3 after they made an awful start - slumping to 8-2 after just 31 balls - in pursuit of Australia's 326.

While there is still work to be done when play resumes on Sunday, Ishant says the India dressing room will remain in high spirits as long as Kohli is out in the middle.

"Whenever [Kohli] is batting, we have to feel pretty confident," he told reporters. "We feel good, because we have finished the day in a strong position.

"Hopefully it can continue tomorrow [Sunday]. Right now, I can say it's equal. Hopefully we will win the first session [on Sunday] and turn the game in our favour."

Cheteshwar Pujara supported his skipper with 24 off 103 balls - during a restorative partnership of 74 - before Ajinkya Rahane added 90 alongside Kohli and ended the day 51 not out.

Ishant credited Pujara for keeping the Australia attack at bay in trademark fashion, while heralding the importance of Rahane's knock after the hosts belatedly made a breakthrough.

"We know that when Pujara defends, the ball doesn't go past," Ishant said. "He is someone you need in your team. I have played against him and I know how difficult it is to bowl to Pujara.

"When he plays, he makes the bowlers really tired, it takes its toll. We know that if he stays on the wicket, he can do wonders for the team. It was very unfortunate the way he got out [caught down the leg side off Mitchell Starc]. We don't get those kind of wickets, bowled down the leg and caught behind.

"Then Ajinkya came in and played some pretty good shots to shift the momentum. We ended the day pretty well."

Virat Kohli and Ajinkya Rahane made unbeaten half-centuries as India battled back against Australia on day two of the second Test, leaving the match in Perth delicately poised. 

A 59-run partnership between Tim Paine (38) and Pat Cummins (19) helped Australia get to 326 before they were bowled out in the first session, with India's response reaching 172-3 by the close of play. 

The tourists had appeared to be in serious trouble after losing opening duo Murali Vijay (0) and KL Rahul (2) in the first six overs of their innings, but Cheteshwar Pujara and Kohli (82 not out) dug in from 8-2 to stop the rot in the second session. 

Nathan Lyon (0-34 from 22 overs) and Cummins (0-40 from 17 overs) combined to give little away in an intense battle with Kohli and Pujara, the two batsmen having to wait more than 21 overs between boundaries before the latter eventually fell for 24 to a great catch from wicketkeeper Paine. 

However, Australia had no answer for an unbroken 90-run stand between the India captain and Rahane, who was on 51 not out at stumps.

The hosts had resumed on 277-6 and after a strong start from Paine and Cummins, the latter was bowled by Umesh Yadav (2-78) and Australia's skipper wasted a review after being trapped leg before by Jasprit Bumrah (2-53). 

Mitchell Starc (6) and Josh Hazlewood (0) edged successive deliveries from Ishant Sharma (4-41) to bring an end to Australia's innings, but they wasted no time in putting India under pressure. 

Starc (2-42) cleaned up Vijay with a full, inswinging delivery to make the breakthrough before lunch and Hazlewood (1-50) dismissed Rahul with a stunning yorker after the break, in the process claiming a second early wicket. 

Kohli sent Hazlewood for three fours in the same over but the boundaries dried up for the tourists during the afternoon. 

Cummins thought he had struck a blow in the absorbing battle by getting Pujara lbw on 23, but ball tracking showed the delivery was going over the top of the stumps. However, there was no doubt when Pujara edged Starc down the leg side and was taken by Paine, leaving India three down. 

Rahane picked up the run-rate immediately, with two fours and a six encouraging Kohli to hammer Cummins over gully and bring up his half-century. 

After back-to-back fours off Hazlewood, Rahane reached 50 with a single off Lyon, his efforts helping put India in a competitive position ahead of what looks to be an intriguing Sunday.

Jasprit Bumrah believes the second Test is still "in the balance", despite a largely difficult first day for India against Australia in Perth.

Australia came through a mini-collapse to take control of the second Test against India after a solid first day in Perth.

Bharat Arun believes India boast one of the best pace bowling attacks they have ever had as they plot to blow Australia away in Perth.

Marcus Harris is backing Mitchell Starc to fire on all cylinders when Australia attempt to level the Test series against India in Perth.

Justin Langer admits there is uncertainty over how the pitch will play at Perth Stadium for Australia's second Test against India, but he hopes to see plenty of pace and bounce.

Australia coach Justin Langer insisted Tim Paine is "100 per cent ready to go" as he dismissed concerns over the captain's fitness heading into the second Test against India.

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