Milan pair Ante Rebic and Rade Krunic have tested positive for coronavirus ahead of Wednesday's Serie A meeting with Juventus.

Both players are asymptomatic and have begun a period of self-isolation at home, Milan confirmed on their official website.

The news comes on the back of Juve announcing that full-backs Alex Sandro and Juan Cuadrado had contracted COVID-19, also ruling them out of the crunch clash at San Siro.

Rebic has featured 14 times for Milan in all competitions this season, while Krunic has been used on 20 occasions.

The pair have appeared together in eight Serie A matches this season, Milan winning each of those games. On the seven occasions they have not featured, meanwhile, the Rossoneri's win rate drops from 100 per cent to 43.

Serie A leaders Milan are already without injured quartet Zlatan Ibrahimovic, Alexis Saelemaekers, Ismael Bennacer and Matteo Gabbia, while Sandro Tonali is suspended.

The club said in a statement: "AC Milan announces that Ante Rebic and Rade Krunic tested positive for a molecular swab carried out yesterday in anticipation of the match against Juventus.

"The players, asymptomatic, remained in isolation at home where a second control swab was taken today. The health authorities were promptly informed.

"All members of the team group underwent a further test today with negative results."

Speaking on Tuesday, doctor Roberto Testi, the director of the Department of Prevention at the Turin ASL, warned the high-profile contest may be called off if Juve report further positive tests on the day of the game.

"If there should be more positive tests and the evidence of an uncontrolled breakout within the squad, that would become a problem of safety for the other players," he told Corriere della Sera.

"Clearly, at that point, the ASL would be forced to intervene, isolating everyone and blocking Juve's departure towards Milan."

Milan enter the game 10 points better off than reigning champions Juventus having played a game more.

Stefano Pioli's men won the most recent encounter between the sides 4-2 last July and are seeking successive league wins in this fixture for the first time since 2010.

It will mark the first time Milan have faced Juve sitting ahead of their rivals in the table since November 2015, when losing 1-0 through a Paulo Dybala goal. 

Manchester City have reportedly annoyed Kevin De Bruyne with their contract offer amid interest in Lionel Messi.

De Bruyne, 29, has been expected to sign a new deal with the Premier League giants, with his contract expiring in 2023.

But with Messi coming out of contract at season's end, City's offer to De Bruyne has seemingly drawn questions.

TOP STORY – MAN CITY ANNOY DE BRUYNE AMID MESSI INTEREST

Manchester City have annoyed De Bruyne with their contract offer, according to The Athletic.

The report says the offer is less than De Bruyne is currently on because of potentially signing Messi. However, the Belgium international is still expected to re-sign.

City have been strongly linked to Messi, who could leave Barcelona at the end of the campaign when is contract is due to expire.

The Barcelona captain has insisted he will not make a decision on his future until the season's conclusion.

ROUND-UP

- Also coming out of contract is Bayern Munich star David Alaba. The Guardian reports Liverpool are interested in signing the defender, but Real Madrid lead the race.

- Staying at Real Madrid and there is uncertainty over Sergio Ramos' future. With his contract expiring at the end of the season, Ramos will not accept a one-year deal and the defender and LaLiga champions are distant in their bid to reach an agreement, according to Marca. The Manchester Evening News reports City are not interested in Ramos.

- Antoine Griezmann is still yet to find his best form for Barcelona, but Sport reports the Blaugrana are not considering selling the forward.

- Mesut Ozil could be set to leave Arsenal. Football.London reports the playmaker, who comes out of contract in June, is in negotiations with MLS franchise DC United.

- Linked with Juventus and Inter, Olivier Giroud is set to stay at Chelsea, according to Goal. They also claim Juve are considering Sampdoria forward Fabio Quagliarella as an alternative, while Milan look set to keep hold of star midfielder Hakan Calhanoglu.

Juventus wide player Juan Cuadrado has tested positive for coronavirus and will miss the clash with Serie A leaders Milan on Wednesday.

The Colombia international is asymptomatic but has begun a period of self-isolation, the Italian champions confirmed.

The news comes just a day after left-back Alex Sandro was ruled out after returning a positive test for the virus.

It means head coach Andrea Pirlo will be without two of his first-choice full-backs for the game at San Siro against Stefano Pioli's side, who are the only unbeaten team in Europe's top five leagues in the 2020-21 season.

The club said in a statement: "Juventus Football Club announces that, during the checks provided for by the protocol in force, Juan Cuadrado has emerged positive with COVID-19. The player has already been placed in solitary confinement and is asymptomatic."

Cuadrado, 32, has made 13 appearances in Serie A this term, scoring once.

Juve head into the Milan contest with a 10-point deficit to the league leaders, albeit with a game in hand.

While they have lost only once in 14 matches, Juve have won just seven times, leaving them in fifth place with 27 points.

They are hoping to avoid losing back-to-back league games against the Rossoneri for the first time since 2010, having been beaten 4-2 in the previous meeting last July.

The last time they faced Milan when behind them in the table was in November 2015, when a Paulo Dybala goal secured a 1-0 victory.

Zlatan Ibrahimovic has been ruled out of the Serie A clash between Milan and Juventus on Wednesday.

The 39-year-old striker has been sidelined since being substituted in the 3-1 win at Napoli on November 22.

The former Manchester United and Paris Saint-Germain star has missed seven league games for the Serie A leaders, although the Rossoneri have fared well in his absence, winning five and drawing two of those matches.

Stefano Pioli's side are alone in Europe's top five leagues in that they have not lost a top-flight match since the 2019-20 season was initially shut down from last March.

They head into the match with champions Juve at San Siro knowing a win would move them 13 points clear of the Bianconeri, who are fifth with a game in hand.

Ibrahimovic had offered hope he could be fit to face his former club after recent injury trouble, posting training footage to social media on Monday with the caption "Tick tock tick tock".

Head coach Pioli, though, says the player is not fully fit and admitted to scolding him for causing a stir two days before the game.

"I told him off because, after that footage, I was peppered with phone calls," Pioli told reporters.

"He is better and he's working well, but he won't be in the game tomorrow."

Rafael Leao has performed well in Ibrahimovic's absence, scoring in the 2-1 win at Sassuolo and the 2-0 victory at Benevento in the past two and a half weeks, becoming the second-youngest foreign player to reach 10 Serie A goals for the club, behind only Alexandre Pato.

Pioli believes the 21-year-old's development is a sign of the way Milan have improved in the past year. The Rossoneri have taken 37 points from their first 15 league matches this term, the first time they have done so in the history of the competition in the three-points-per-win era.

“He’s growing a lot, he has characteristics that we must try to enhance in the right way," said Pioli. "The important thing is to see the will to grow and improve on a daily basis.

"All matches are opportunities to prove our worth. We have to concentrate on the game and raise our level because they are strong opponents, with experience, and they have been winning for years.

"We're showing we can play for it and we'll therefore play to win. We have scored 17 points more than last year. This is the right path, but we can't speak of a decisive match after 15 rounds."

Cristiano Ronaldo's performance will be decisive when Juventus meet Milan in a huge Serie A clash on Wednesday, says Andrea Pirlo.

The Juve forward has racked up 14 goals in 11 Serie A games this season, netting a double and adding an assist in Sunday's 4-1 thumping of Udinese.

Pirlo will take charge of a match against Milan, with whom he spent a decade as a player and won the Champions League twice, for the first time.

Despite Ronaldo's form, Juve sit 10 points adrift of impressive leaders Milan, albeit the Bianconeri have a game in hand. 

"From the beginning we have tried to exploit Cristiano for his characteristics, clarity and incisiveness in the final third," said Juve boss Pirlo ahead of the San Siro battle.

"Is he decisive? Of course, as he was everywhere. 

"But it is normal to depend on him when you have such a champion in your team."

With the pressure on for a crucial clash, Pirlo feels it is Milan and not defending champions Juve who are currently the team to beat.

"Milan have not lost in a long time, they are first in the standings and they are the team to beat," he said.

"I see a great spirit in Milan, which leads them to win games. They come into the game off the back of excellent results, they fight and run together and they don't want to lose.

"The table always reflects the values of the championship. We play game after game to move up the standings, looking only at ourselves. We will see in April where we will be.

"We will try to impose our game at San Siro, without fear: these are the good matches to be involved in."

He added: "It will be a special evening for me, having experienced many memories with Milan. It was wonderful as a player, I think it will be the same as a coach.

"We know the importance of the match. We will play our game and do our best. It will be very important, but not decisive.

"We will need to be good at making few mistakes and to play well, technically, in order to not give space to Milan's breakaways, which is one of their strengths.

"In the Italian league you can't give up, not even for a second - every match must be faced with the same concentration. I want to see a Juve convinced of their strength, who play the game we have in mind."

Pirlo was asked for an update on available players after Alex Sandro tested positive for coronavirus.

"After Alex Sandro tested positive, we will have the results of the team's tests in the afternoon - until then we wait," he said.

"[Paulo] Dybala is doing pretty well, he is better after his fever so should be available for the game.

"[Alvaro] Morata is recovering and doing physiotherapy, [Giorgio] Chiellini and [Merih] Demiral are doing quite well, while Arthur and [Adrien] Rabiot have both recovered. 

"On Wednesday, we will evaluate who we will have available to bring to Milan. There will be no excuse for the game - the squad is competitive in all sectors. Other teams have had the same problems."

Milan won 4-2 against Juve in July, so they are looking for back-to-back wins against Juventus in Serie A for the first time since 2010, when Pirlo was playing at San Siro under Leonardo.

Juventus defender Alex Sandro has tested positive for coronavirus, the Serie A club announced on Monday.

The Brazil international - who played in Sunday's 4-1 league victory over Udinese in Turin - underwent a test after displaying what Juve described as "mild symptoms". 

Alex Sandro is self-isolating after it was confirmed he has contracted COVID-19, a concern for his club ahead of Wednesday's huge showdown with Milan.

"Juventus announces that following the appearance of some mild symptoms, a check was arranged for the player Alex Sandro, which revealed his positivity to COVID-19," a statement read.

"The player has already been placed in isolation. 

"The club is in contact with the health authorities for the definition of an effective implementation of the protocols needed to allow the training and competition activities of the team."

Alex Sandro featured for 83 minutes against Udinese before being replaced by Gianluca Frabotta, at which stage the hosts were 3-0 up in the game.

The 29-year-old has made seven league appearances under Andrea Pirlo during the 2020-21 campaign, as well as featuring three times in the Champions League group stage.

Juve travel to San Siro to face Milan - the unbeaten Serie A leaders - in midweek, followed by a home game against Sassuolo on Sunday.

Andrea Pirlo revealed Juventus were "feeling the fear" from their heavy defeat to Fiorentina before the mid-season break in the early stages of their 4-1 win over Udinese on Sunday. 

Juve suffered a humiliating 3-0 home loss to La Viola in December – their first in the league this season – but the champions bounced back to winning ways in style at the Allianz Stadium. 

Cristiano Ronaldo scored either side of Federico Chiesa's cool finish – the 15th consecutive season the Portugal star has scored 20 goals for club and country – before Udinese's Marvin Zeegelaar and Paulo Dybala exchanged goals in the closing stages. 

The result ensured Juve avoided going three consecutive home games without a win for the first time since 2015-16, and Pirlo conceded the defeat to Fiorentina last time out was on his players' minds early on.

"It wasn't the best Juventus, as we were coming off a bad defeat to Fiorentina, so started quite timid and nervous, especially when their forwards ran towards us. We gained more confidence as it went on," Pirlo told DAZN.

"I was not satisfied with the initial approach to the game, as we were still feeling the fear of our last defeat to Fiorentina. The timing of the movements weren't right, especially on the wings.

"We knew that Udinese would try to sit back, counter and wait for our mistakes, but we did well with the preventative marking to ensure they couldn't do that."

Dybala's late goal was just his second in Serie A this season and came after a game in which he lost possession 21 times – seven more than any other Juve player.

Despite his wastefulness with the ball, Pirlo was pleased with the Argentina international's contribution and believes his goal was the result of the forward's improved fitness. 

"We need Dybala, he needs us," the Juve boss added. "He worked very well during the week in training. We could tell during the match that he was in better physical condition and we kept him on to the end because we hoped he would score that goal."

The result could have been different had Rodrigo De Paul's 10th-minute strike not been ruled out following a VAR check for a handball earlier in the move. 

And Rodrigo Bentancur, who laid on Ronaldo's second, acknowledged Juve need to start games with more of a spring in their step, starting with their visit to leaders Milan on Wednesday. 

"We didn't start with the right mentality and conceded that goal, which fortunately was disallowed for handball," Bentancur said. 

"We did better after the break, deserved the victory, but again the mentality dropped at the end to concede that goal.

"I think we need to keep that concentration throughout the 90 minutes. We allowed Udinese too many chances and that should not happen.

"I don't mind if I score goals or not. I provided an assist tonight and that's as good as a goal, because I am helping the team.

"This was a victory we wanted and fought hard for. Now we have a couple of days to rest and prepare for Milan."

Cristiano Ronaldo scored twice as Juventus bounced back from their Fiorentina fiasco with a 4-1 win over Udinese at the Allianz Stadium on Sunday. 

Andrea Pirlo's side suffered a humiliating 3-0 home defeat to La Viola before the mid-season break, but they kicked off 2021 with a win that ensured the gap to Serie A leaders Milan remained at 10 points. 

Ronaldo put Juve ahead in the 31st minute with a fine strike after Udinese's Rodrigo de Paul had seen an effort ruled out by VAR. 

Federico Chiesa and Ronaldo then made sure Juve avoided going three consecutive home games without a win for the first time since 2015-16.

Marvin Zeegelaar snatched a consolation for Udinese, but Paulo Dybala had the final say in stoppage time.

Jadon Sancho was once top of Manchester United 's wish list but now Ole Gunnar Solskjaer wants to move for the Borussia Dortmund star's teammate  Erling Haaland .

Solskjaer had solidified his position at United heading into the January window following a 10-match unbeaten run and the Norwegian manager is determined to recruit his countryman.

After tracking ex-Manchester City youth product Sancho before the season, United are ready to switch their attention to Haaland, with reports suggesting he has a £70million release clause.

TOP STORY – UNITED TO SWITCH ATTENTION TO HAALAND AND CASH IN ON POGBA

The Mirror report Solskjaer is so keen on Haaland, he flew to Salzburg and attempted to hijak the goalscoring sensation’s move to Dortmund last January.

Real Madrid are reportedly close to agreeing a deal with David Alaba, while Manchester United are expecting the asking price for Jadon Sancho to drop.

Alaba, 28, is set to leave Bayern Munich with his contract expiring at the end of the season.

The defender is free to speak to other clubs, and Madrid are making their move.

TOP STORY – MADRID CLOSE TO ALABA SIGNING

Real Madrid are close to landing Bayern Munich defender Alaba on a four-year deal, according to Marca.

Alaba is likely to have offers from multiple clubs after establishing himself as one of Europe's leading defenders.

The Austria international has won nine Bundesliga titles and two Champions Leagues among numerous other trophies with Bayern.

ROUND-UP

- With Jadon Sancho yet to hit top form for Borussia Dortmund this season, Manchester United may be able to land the attacker later this year. 90min reports United believe they can land Sancho for less than £100million (€112.7m) after not meeting Dortmund's valuation of £107m (€120m) in the close season.

- Lionel Messi's future remains a major talking point. Sport reports the Barcelona star – who is out of contract at the end of the campaign – will wait until the end of the season to decide between the LaLiga giants, Manchester City, Paris Saint-Germain and MLS.

- Real Madrid are apparently eyeing a replacement for Marcelo. AS reports the LaLiga giants are tracking Sporting CP left-back Nuno Mendes, who is also linked to Liverpool, Manchester United, Juventus and PSG.

- Liverpool are also linked with centre-backs after long-term injuries to Virgil van Dijk and Joe Gomez, while potential exits have been mentioned. However, the Liverpool Echo reports the Premier League giants are not expecting any senior departures in January, which would mean Xherdan Shaqiri and Divock Origi remain despite speculation over their futures.

Manchester City are reportedly planning a bid for Harry Kane, while United are still interested in Jack Grealish.

City have been linked with numerous forwards amid uncertainty over Sergio Aguero's future.

And it seems the Tottenham star is among their targets.

TOP STORY – MAN CITY PLANNING £88.7M BID FOR KANE

Manchester City are planning an £88.7million offer for Tottenham star Kane ahead of next season, according to Bild.

Kane, 27, is contracted at Spurs, where he continues to star, until 2024.

The England international has scored nine goals in 15 Premier League games this season.

ROUND-UP

- Manchester United remain interested in signing Aston Villa star Grealish, according to the Daily Mail. The midfielder was heavily linked with a move to United in the close season, but ended up staying at Villa, who are in action at Old Trafford on Friday.

- Eric Garcia has seemingly made a decision on his future. The Guardian reports the Manchester City defender has agreed personal terms on a five-year deal with Barcelona. Garcia is contracted at City until the end of the season.

- With Mauricio Pochettino reportedly set to take over at Paris Saint-Germain, Tottenham apparently have worries over Hugo Lloris. The Sun reports Spurs fear the goalkeeper could join former boss Pochettino in Paris and they are eyeing West Brom's Sam Johnstone and Manchester United's Dean Henderson as potential targets.

- Yet to play for Arsenal this season, Mesut Ozil's future remains a talking point. Bild reports the playmaker wants to see out his contract, which runs until season's end, with the Premier League outfit.

- Also coming out of contract, Sami Khedira looks set for a Juventus exit. The Daily Mail reports the midfielder is set to hold talks with Everton over a potential move.

- Struggling for game time at Manchester United, Jesse Lingard has had the one-year option on his contract at the club triggered, according to Sky Sports. Lingard's deal now runs until 2022.